Catalog No.
YHJ69701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala162
Predicted molecular weight
20.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NZH8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interleukin-1 homolog 1, IL1H1, IL-1H1, IL-1RP2, IL-1 epsilon, IL1E, IL-1F9, IL36G, IL-1-related protein 2, Interleukin-1 family member 9, IL1RP2, Interleukin-36 gamma, Interleukin-1 epsilon, IL1F9
Increased IL- 36γ in visceral adipose tissue as a key mediator of obesity-driven inflammation in colon cancer., PMID:40268791
Clinical Responses and Transcriptomic Analysis of Spesolimab in a Girl With Severe Dermatitis, Multiple Allergies and Metabolic Wasting Syndrome., PMID:40207438
Monocytes Expressing IL-36G Play a Crucial Role in Atopic Dermatitis., PMID:40159643
LL37 complexed to double-stranded RNA induces RIG-I-like receptor signalling and Gasdermin E activation facilitating IL-36γ release from keratinocytes., PMID:40121229
Epigenetic insights into fertility: involvement of immune cell methylation in dairy cows reproduction., PMID:39908274
An S100A8/A9 Neutralizing Antibody Potently Ameliorates Contact Hypersensitivity and Atopic Dermatitis Symptoms., PMID:39848567
Inflammatory Response of THP1 and U937 Cells: The RNAseq Approach., PMID:39768153
Characterising the transcriptomic response of bovine peripheral blood mononuclear cells to a mycobacterial cell wall fraction., PMID:39566357
Sublingual Immunotherapy Decreased the Serum Levels of Interleukin-36γ in Allergic Rhinitis., PMID:39544181
Gene expression profiling reveals host defense strategies for restricting Candida albicans invasion and gastritis to the limiting ridge of the murine stomach., PMID:39535200
Analysis of the role of IL-1 family and related genes in head and neck squamous cell carcinoma., PMID:39461030
Vasopressin drives aberrant myeloid differentiation of hematopoietic stem cells, contributing to depression in mice., PMID:39442524
IL36G-producing neutrophil-like monocytes promote cachexia in cancer., PMID:39266531
Targeting the STAT3/IL-36G signaling pathway can be a promising approach to treat rosacea., PMID:38909883
Secukinumab and Dead Sea Climatotherapy Impact Resolved Psoriasis Skin Differently Potentially Affecting Disease Memory., PMID:38892277
IL27 and IL1RN are causally associated with acute pancreatitis: a Mendelian randomization study., PMID:38742942
Neutrophil-driven and interleukin-36γ-associated ocular surface inflammation in chronic Stevens-Johnson syndrome., PMID:38682250
Suppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory feedback cycle involving IL-17RA/IL-17RE epidermal signaling., PMID:38470486
IL-36 Regulates Neutrophil Chemotaxis and Bone Loss at the Oral Barrier., PMID:38414292
Identification of characteristic genes and herbal compounds for the treatment of psoriasis based on machine learning and molecular dynamics simulation., PMID:38344924
Interleukin-36gamma Mediates the In Vitro Activation of CD8+ T Cells from Patients Living with Chronic Human Immunodeficiency Virus-1 Infection., PMID:38301135
Understanding the impact of risankizumab on keratinocyte-derived IL-23A in a novel organotypic 3D skin model containing IL-23A responsive and IL-17A producing γδ-T-cells., PMID:38284163
Single-cell transcriptome analysis reveals keratinocyte subpopulations contributing to psoriasis in corneum and granular layer., PMID:38279596
Human interleukin-36γ plays a crucial role in cytokine induction during Sporothrix brasiliensis and S. schenckii infection in keratinocytes and PBMCs., PMID:38262494
Impaired local Vitamin D3 metabolism contributes to IL-36g overproduction in epithelial cells in chronic rhinosinusitis with nasal polyps., PMID:38085113
Mature IL-36γ Induces Stratum Corneum Exfoliation in Generalized Pustular Psoriasis by Suppressing Corneodesmosin., PMID:37827276
Transcriptional analysis of human peripheral blood mononuclear cells stimulated by Mycobacterium tuberculosis antigen., PMID:37818041
Multi-omics segregate different transcriptomic impacts of anti-IL-17A blockade on type 17 T-cells and regulatory immune cells in psoriasis skin., PMID:37781383
Elevated serum IL-36γ levels in patients with ankylosing spondylitis and its association with disease activity., PMID:37768497
Co-occurrence of non-alcoholic steatohepatitis exacerbates psoriasis associated with decreased adiponectin expression in a murine model., PMID:37646025
Interleukin-38: A crucial player in periodontitis., PMID:37455397
Psoriasis and Leprosy: An Arcane Relationship., PMID:37337513
IL36G genetic variant is independently associated with susceptibility, severity and joint involvement in psoriasis., PMID:37285630
Single-cell transcriptomics suggest distinct upstream drivers of IL-17A/F in hidradenitis versus psoriasis., PMID:37271319
Elucidating the NB-UVB mechanism by comparing transcriptome alteration on the edge and center of psoriatic plaques., PMID:36928592
Oleic acid-induced interleukin-36γ: A possible link between facial skin redness and sebum., PMID:36891608
Temporal Release of IL-1 Family Members from Virally Infected Airway Epithelial Cells Suggests IL-36γ Is the Early Responder., PMID:36856413
IL-36γ Augments Ocular Angiogenesis by Promoting the Vascular Endothelial Growth Factor-Vascular Endothelial Growth Factor Receptor Axis., PMID:36740182
Luteolin alleviated neutrophilic asthma by inhibiting IL-36γ secretion-mediated MAPK pathways., PMID:36604842
Cathelicidin Antimicrobial Peptide LL37 Induces Toll-Like Receptor 8 and Amplifies IL-36γ and IL-17C in Human Keratinocytes., PMID:36496195
Particulate matter 2.5 induces the skin barrier dysfunction and cutaneous inflammation via AhR- and T helper 17 cell-related genes in human skin tissue as identified via transcriptome analysis., PMID:36471583
Clinical significance of elevated serum IL-36γ levels in patients with early-stage Hashimoto's thyroiditis., PMID:36470344
Corrigendum: IL36G is associated with cutaneous antiviral competence in psoriasis., PMID:36325341
Host cell transcriptomic response to the multidrug-resistant Mycobacterium tuberculosis clonal outbreak Beijing strain reveals its pathogenic features., PMID:36242542
L36G is associated with cutaneous antiviral competence in psoriasis., PMID:36172384
Plasma IL-36α and IL-36γ as Potential Biomarkers in Interstitial Lung Disease Associated with Rheumatoid Arthritis: a Pilot Study in the Chinese Population., PMID:36044099
Treponema denticola Induces Interleukin-36γ Expression in Human Oral Gingival Keratinocytes via the Parallel Activation of NF-κB and Mitogen-Activated Protein Kinase Pathways., PMID:36040155
IL-36 Cytokines: Their Roles in Asthma and Potential as a Therapeutic., PMID:35903102
Proprotein convertase subtilisin/kexin type 9 is a psoriasis-susceptibility locus that is negatively related to IL36G., PMID:35862195
IL-36 is Closely Related to Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease., PMID:35698471
For research use only. Not for human or drug use.
