Catalog No.
YHJ69401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser102
Predicted molecular weight
14.15 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NZD4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EDRF, ERAF, AHSP, Erythroid differentiation-related factor, Erythroid-associated factor, Alpha-hemoglobin-stabilizing protein
Genetic polymorphism of novel SNP rs5006884 in OR51B6 and SNP rs4499252 in AHSP among transfusion-dependent and non-transfusion-dependent β-thalassemia/Hb E patients in Thailand: a multivariate analysis of clinical and genetic polymorphism., PMID:40377674
Proteomic analysis of urine reveals biomarkers for identification of kidney injury in children's abdominal-type Henoch-Schönlein purpura., PMID:40289489
Molecular basis identification and hypnotic drug interactions for cognitive impairment related to sleep deprivation., PMID:40229714
Blood-brain barrier crossing biopolymer targeting c-Myc and anti-PD-1 activate primary brain lymphoma immunity: Artificial intelligence analysis., PMID:40088978
Impact of liquid and solid-state cultures on hemoglobin production and oxidative state in Saccharomyces cerevisiae., PMID:39929304
ANK1 inhibits malignant progression of osteosarcoma by promoting ferroptosis., PMID:39217322
Therapeutic Relevance of Inducing Autophagy in β-Thalassemia., PMID:38891049
Increased Expression of α-Hemoglobin Stabilizing Protein (AHSP) mRNA in Erythroid Precursor Cells Isolated from β-Thalassemia Patients Treated with Sirolimus (Rapamycin)., PMID:38731008
Impact of α-Globin Gene Expression and α-Globin Modifiers on the Phenotype of β-Thalassemia and Other Hemoglobinopathies: Implications for Patient Management., PMID:38542374
Silver Coordination Polymers Driven by Adamantoid Blocks for Advanced Antiviral and Antibacterial Biomaterials., PMID:38456838
Gene expression in multiple sclerosis during pregnancy based on integrated bioinformatics analysis., PMID:38154347
Gene expression analysis revealed downregulation of complement receptor 1 in clonal B cells in cold agglutinin disease., PMID:38133636
MicroRNA and Protein Cargos of Human Limbal Epithelial Cell-Derived Exosomes and Their Regulatory Roles in Limbal Stromal Cells of Diabetic and Non-Diabetic Corneas., PMID:37947602
Artificial intelligence differentiates abdominal Henoch-Schönlein purpura from acute appendicitis in children., PMID:37905746
Keap1-Nrf2 Heterodimer: A Therapeutic Target to Ameliorate Sickle Cell Disease., PMID:36978988
Digital image analysis of erythroblastic islands in myelodysplastic syndromes., PMID:36946202
Identification of key genes and pathways associated with gender difference in osteonecrosis of the femoral head based on bioinformatics analysis., PMID:36856107
Alpha-Hemoglobin Stabilizing Protein Gene Polymorphism (rs4499252 A/G) and its Association with Beta-Thalassemia Major in Iraqi Patients., PMID:36618286
Association between physical activity, sedentary time, and physical fitness of female college students in China., PMID:36476426
iPSC-neural crest derived cells embedded in 3D printable bio-ink promote cranial bone defect repair., PMID:36333414
Computational gene expression analysis reveals distinct molecular subgroups of T-cell prolymphocytic leukemia., PMID:36129940
A Bioinformatics Study of Ropivacaine plus Dexamethasone Prolonging the Duration of Nerve Block., PMID:35990127
Integrated bioinformatics analysis reveals marker genes and immune infiltration for pulmonary arterial hypertension., PMID:35710932
Age and sex effects across the blood proteome after ionizing radiation exposure can bias biomarker screening and risk assessment., PMID:35487913
Identification of differentially expressed genes associated with coronary in-stent restenosis by integrated bioinformatics approaches., PMID:35144391
Nrf2 expands the intracellular pool of the chaperone AHSP in a cellular model of β-thalassemia., PMID:35092867
Redox-Regulation of α-Globin in Vascular Physiology., PMID:35052663
mRNA Analysis of Frameshift Mutations with Stop Codon in the Last Exon: The Case of Hemoglobins Campania [α1 cod95 (-C)] and Sciacca [α1 cod109 (-C)]., PMID:34680508
Alpha haemoglobin-stabilising protein concentration in the red blood cells of patients with sickle cell anaemia with and without hydroxycarbamide treatment., PMID:34378186
Improved production of human hemoglobin in yeast by engineering hemoglobin degradation., PMID:33984513
CHIP phosphorylation by protein kinase G enhances protein quality control and attenuates cardiac ischemic injury., PMID:33082318
Transient Improvement in Erythropoiesis Is Achieved Via the Chaperone AHSP With Early Administration of Propranolol in Burn Patients., PMID:32842148
Effect of Mutations on mRNA and Globin Stability: The Cases of Hb Bernalda/Groene Hart and Hb Southern Italy., PMID:32751969
Stage Specific Expression Pattern of Alpha-Hemoglobin-Stabilizing-Protein (AHSP) Portrayed in Erythroblast Chronology., PMID:32629835
Further Characterization of Hb Bronovo [α103(G10)His→Leu; HBA2: c.311A>T] and First Report of the Homozygous State., PMID:32552204
Bone-chip system to monitor osteogenic differentiation using optical imaging., PMID:32296299
Alpha-hemoglobin-stabilizing protein (AHSP): a modulatory factor in β-thalassemia., PMID:31894534
Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients., PMID:31628103
Curating the gnomAD database: Report of novel variants in the globin-coding genes and bioinformatics analysis., PMID:31553106
DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis., PMID:31464599
Blood-brain barrier permeable nano immunoconjugates induce local immune responses for glioma therapy., PMID:31462642
Genetic signature related to heme-hemoglobin metabolism pathway in sepsis secondary to pneumonia., PMID:31396396
Versican is crucial for the initiation of cardiovascular lumen development in medaka (Oryzias latipes)., PMID:31263118
Association of alpha hemoglobin-stabilizing protein (AHSP) gene mutation and disease severity among HbE-beta thalassemia patients., PMID:31190133
The Chaperones Involved in Hemoglobin Synthesis Take the Spotlight: Analysis of AHSP in the Argentinean Population and Review of the Literature., PMID:30558442
Endothelial cell α-globin and its molecular chaperone α-hemoglobin-stabilizing protein regulate arteriolar contractility., PMID:30295646
Recent Advances and Future of Gene Therapy for Bone Regeneration., PMID:29909597
A comprehensive review of the prevalence of beta globin gene variations and the co-inheritance of related gene variants in Saudi Arabians with beta-thalassemia., PMID:29619482
Exosome-Mediated Benefits of Cell Therapy in Mouse and Human Models of Duchenne Muscular Dystrophy., PMID:29478899
The effect of histone deacetylase inhibitors on AHSP expression., PMID:29389946