Catalog No.
YHJ67201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His29-Ser209
Predicted molecular weight
21.72 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NSA1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FGF21, Fibroblast growth factor 21, FGF-21
Circulating FGF21 and Ketone Bodies Modify the Risk of MASLD and Mortality: Insights from the PREVEND Cohort Study., PMID:40507869
Genetically predicted immune cells mediates the association between hepatocellular carcinoma and inflammatory proteins: a Mendelian randomization study., PMID:40504445
A Biological-Systems-Based Analyses Using Proteomic and Metabolic Network Inference Reveals Mechanistic Insights into Hepatic Lipid Accumulation: An IMI-DIRECT Study., PMID:40502600
Fibroblast growth factor 21/extracellular signal-regulated kinase 1/2 pathway as a key link mediates the effects of low-protein diet on skeletal muscle fiber type transformation in pigs., PMID:40487094
Poria cocos polysaccharides alleviate obesity-related adipose tissue insulin resistance via gut microbiota-derived short-chain fatty acids activation of FGF21/PI3K/AKT signaling., PMID:40484558
New Approach Combination-Dosed Therapy for Nonalcoholic Steatohepatitis Versus Vitamin E: A Randomized Controlled Trial., PMID:40480879
Circulating Fibroblast Growth Factor-21 in Patients with Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis., PMID:40465044
Role of CCK1 receptor in metabolic benefits of intestinal enteropeptidase inhibition in mice., PMID:40460092
The Predictive Role of FGF21 in Acute Liver Injury Caused by Bacterial Infectious Diseases in Critical Care: A Retrospective Cohort Study., PMID:40453967
FGF21 alleviates α-II-spectrin breakdown in a model of oxygen-glucose deprivation and modulates global protein phosphorylation in hippocampal neurons., PMID:40447258
Promotion of obesity by fibroblast growth factor 21-oxytocin system dysfunction due to sugar-specific hyperphagia., PMID:40445899
Brain-acting hepatokines: its impact on energy balance and metabolism., PMID:40443802
hpCasMINI: An engineered hypercompact CRISPR-Cas12f system with boosted gene editing activity., PMID:40442121
Analysis of the correlation between inflammatory cytokines and glioblastoma: A Mendelian randomization study., PMID:40441232
ALKBH5 mediates FGF21 m6A demethylation in human bone marrow mesenchymal stem cells under high glucose conditions., PMID:40441069
Effect of exercise on Fibroblast Growth Factor 21 levels in healthy males and females., PMID:40440637
Ethanol induction of FGF21 in the liver is dependent on histone acetylation and ligand activation of ChREBP by glycerol-3-phosphate., PMID:40440069
Bridging systemic metabolic dysfunction and Alzheimer's disease: the liver interface., PMID:40437610
Dietary Insulinogenic Amino Acid Restriction Improves Glucose Metabolism in a Neonatal Piglet Model., PMID:40431415
Effects of Intermittent Fasting on Liver Steatosis and Fibrosis, Serum FGF-21 and Autophagy Markers in Metabolic Dysfunction-Associated Fatty Liver Disease: A Randomized Controlled Trial., PMID:40430125
Fgf21 Deficiency Delays Hair Follicle Cycling and Modulates miRNA-Target Gene Interactions in Mice., PMID:40427715
FAM172A deletion aggravates high fat diet-induced MASLD via the eIF2α-ATF4-FGF21 loop., PMID:40425140
FGF-21 fusion proteins ameliorate atopic dermatitis by inhibiting the TLR/TSLP signaling pathway: Anti-inflammatory and skin barrier repair effects., PMID:40424659
[Study of the role of biomarkers in determining the course of non-alcoholic fatty liver disease in children with obesity]., PMID:40418137
Fetal macrosomia and placental expression of fibroblast growth factor 21 and peroxisome proliferator-activated receptor alpha., PMID:40411500
Association of neurobiological and immune serum biomarkers with Toxoplasma gondii infection in patients with schizophrenia., PMID:40397143
Higher circulating FGF21, lower protein intake, and lower muscle mass: Associations with a higher risk of mortality., PMID:40390366
Association between circulating inflammatory proteins and gout: A Mendelian randomization study., PMID:40388724
Effect of Fenofibrate on Markers of Gut Barrier Function in Dogs With Naturally Occurring Diabetes Mellitus., PMID:40384217
Blockade of the estrogen receptor alpha-pregnane X receptor axis protects ovariectomized mice against ethanol-induced hepatotoxicity., PMID:40381698
Changes in microbial and metabolic profiles of mice fed with long-term high salt diet., PMID:40375136
Sodium-Glucose Cotransporter 2 Inhibitor Ameliorate Angiotensin II-Induced Hypertension and Vascular Injury by Upregulating FGF21., PMID:40369373
Target Populations for Novel Triglyceride-Lowering Therapies., PMID:40368577
FGF21 reverses MASH through coordinated actions on the CNS and liver., PMID:40367940
Combination of Berberine and Evodiamine Alleviates Obesity by Promoting Browning in 3T3-L1 Cells and High-Fat Diet-Induced Mice., PMID:40362407
Tryptophan Hydroxylase 1 Regulates Tryptophan and Its Metabolites., PMID:40362217
Circulating fibroblast growth factor 21 is associated with blood pressure in the Chinese population: a community-based study., PMID:40356318
[Lycopene ameliorates D-galactose-induced hepatic senescence in CD-1 female mice through fibroblast growth factor 21/mitochondrial dynamics mediation]., PMID:40355334
Proteomic Analysis of Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy (VANISH) Clinical Trial., PMID:40340372
Causal relationship between circulating inflammatory proteins and atherosclerosis: a bidirectional Mendelian randomization study and meta-analysis., PMID:40339743
The potential role of adipokines and hepatokines in age-related ocular diseases., PMID:40330313
Identification of potential anti aging drugs and targets in chronic kidney disease., PMID:40319112
TSG attenuated NAFLD and facilitated weight loss in HFD-fed mice via activating the RUNX1/FGF21 signaling axis., PMID:40307458
Acalabrutinib alleviates metabolic dysfunction-associated steatotic liver disease by regulating bile acid metabolism., PMID:40306481
Metabolism-related hepatokines change in biliary atresia: ANGPTL6 as a potential biomarker., PMID:40281461
MOB1 deletion in murine mature adipocytes ameliorates obesity and diabetes., PMID:40258148
Molecular Biomarkers of Neurodegeneration in Amyotrophic Lateral Sclerosis., PMID:40254405
Stimuli-responsive hydrogel with spatiotemporal co-delivery of FGF21 and H₂S for synergistic diabetic wound repair., PMID:40252979
Systemic effect of combined functional overload and endurance-type swimming exercise on whole body metabolism in mice., PMID:40248969
Activin B improves glucose metabolism via induction of Fgf21 and hepatic glucagon resistance., PMID:40246973
For research use only. Not for human or drug use.
