Catalog No.
YHJ64501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly389-Arg587
Predicted molecular weight
23.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NQ94
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ACF, ASP, APOBEC1 complementation factor, A1CF, APOBEC1-stimulating protein
APOBEC-1 Complementation Factor: From RNA Binding to Cancer., PMID:39334524
Genetic alteration of mRNA editing enzyme APOBEC3B in the pathogenesis of ovarian endometriosis., PMID:39197402
Identification of RBM46 as a novel APOBEC1 cofactor for C-to-U RNA-editing activity., PMID:38708190
A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells., PMID:38612387
Recapitulation of patient-specific 3D chromatin conformation using machine learning., PMID:37673071
Characterization of molecular subtypes based on chromatin regulators and identification of the role of NPAS2 in lung adenocarcinoma., PMID:37120564
Polychlorinated biphenyls alter hepatic m6A mRNA methylation in a mouse model of environmental liver disease., PMID:36341798
Transcriptional Regulation of Human Arylamine N-Acetyltransferase 2 Gene by Glucose and Insulin in Liver Cancer Cell Lines., PMID:36156098
Genetically-biased fertilization in APOBEC1 complementation factor (A1cf) mutant mice., PMID:35948620
Genetic risk of hyperuricemia in hypertensive patients associated with antihypertensive drug therapy: A longitudinal study., PMID:35023146
RNA binding motif 47 (RBM47): emerging roles in vertebrate development, RNA editing and cancer., PMID:34499322
APOBEC1 mediated C-to-U RNA editing: target sequence and trans-acting factor contribution to 177 RNA editing events in 119 murine transcripts in-vivo., PMID:34083494
APOBEC1 complementation factor facilitates cell migration by promoting nucleus translocation of SMAD3 in renal cell carcinoma cells., PMID:34002283
Investigations of Kidney Dysfunction-Related Gene Variants in Sickle Cell Disease Patients in Cameroon (Sub-Saharan Africa)., PMID:33790942
easyCLIP analysis of RNA-protein interactions incorporating absolute quantification., PMID:33692367
Both variants of A1CF and BAZ1B genes are associated with gout susceptibility: a replication study and meta-analysis in a Japanese population., PMID:33517564
Apobec1 complementation factor overexpression promotes hepatic steatosis, fibrosis, and hepatocellular cancer., PMID:33445170
High APOBEC1 Complementation Factor Expression Positively Modulates the Proliferation, Invasion, and Migration of Endometrial Cancer Cells Through Regulating P53/P21 Signaling Pathway., PMID:32818382
Interactomics Analyses of Wild-Type and Mutant A1CF Reveal Diverged Functions in Regulating Cellular Lipid Metabolism., PMID:32786677
Integrated Analysis of the Functions and Prognostic Values of RNA Binding Proteins in Lung Squamous Cell Carcinoma., PMID:32194639
A1CF-promoted colony formation and proliferation of RCC depends on DKK1-MEK/ERK signal axis., PMID:31881249
The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative RNA Splicing., PMID:31597092
Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells., PMID:31186064
Long-Term Intensive Lifestyle Intervention Promotes Improvement of Stage III Diabetic Nephropathy., PMID:31022160
Comparison of RNA Editing Activity of APOBEC1-A1CF and APOBEC1-RBM47 Complexes Reconstituted in HEK293T Cells., PMID:30844405
A1CF-Axin2 signal axis regulates apoptosis and migration in Wilms tumor-derived cells through Wnt/β-catenin pathway., PMID:30825095
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions., PMID:30698716
Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver., PMID:30309881
Multiple Membrane Transporters and Some Immune Regulatory Genes are Major Genetic Factors to Gout., PMID:30123371
Expansion of the ISWI chromatin remodeler family with new active complexes., PMID:28801535
Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout., PMID:28679452
Apobec-1 complementation factor regulates cell migration and apoptosis through Dickkopf1 by acting on its 3' untranslated region in MCF7 cells., PMID:28639893
APOBEC1 complementation factor (A1CF) is dispensable for C-to-U RNA editing in vivo., PMID:28069890
Parent-of-origin effects of A1CF and AGO2 on testicular germ-cell tumors, testicular abnormalities, and fertilization bias., PMID:27582469
Variation in the Calculation of Allostatic Load Score: 21 Examples from NHANES., PMID:27352114
EIYMNVPV Motif is Essential for A1CF Nucleus Localization and A1CF (-8aa) Promotes Proliferation of MDA-MB-231 Cells via Up-Regulation of IL-6., PMID:27231908
Chromosomal mapping of the αMHC-MerCreMer transgene in mice reveals a large genomic deletion., PMID:27165291
Apobec-1 Complementation Factor (A1CF) Inhibits Epithelial-Mesenchymal Transition and Migration of Normal Rat Kidney Proximal Tubular Epithelial Cells., PMID:26848653
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase., PMID:25902538
Re-editing the paradigm of Cytidine (C) to Uridine (U) RNA editing., PMID:25585043
The relationship of apolipoprotein B and very low density lipoprotein triglyceride with hyperuricemia and gout., PMID:25432151
C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47., PMID:24916387
Are differences between patient and provider explanatory models of diabetes associated with patient self-management and glycemic control?, PMID:24185147
Current state of type 2 diabetes management., PMID:23844829
The A1C: making history., PMID:23409297
An application of a diabetes knowledge scale for low-literate Hispanic/Latinos., PMID:23362334
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations., PMID:23263486
Transgenerational epigenetic effects of the Apobec1 cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viability., PMID:22923694
Human CCAAT/enhancer-binding protein β interacts with chromatin remodeling complexes of the imitation switch subfamily., PMID:22242598
Binding site specificity and factor redundancy in activator protein-1-driven human papillomavirus chromatin-dependent transcription., PMID:21937452
For research use only. Not for human or drug use.
