Catalog No.
YHJ60901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr33-Ser170
Predicted molecular weight
18.49 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9HCT0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FGF-22, Fibroblast growth factor 22, FGF22
Fibroblast growth factor 22., PMID:40139106
Identifcation of the FGF family as therapeutic targets and prognostic biomarkers in the microenvironment of head and neck squamous cell carcinoma., PMID:40086631
Pentraxin 3 promotes microglial M2 polarization and excitatory synapse formation in the hippocampus in depression., PMID:39736239
Hypothyroidism Promotes Microglia M1 Polarization by Inhibiting BDNF-Promoted PI3K-Akt Signaling Pathway., PMID:39631379
Transcriptomic landscape of quiescent and proliferating human corneal stromal fibroblasts., PMID:39243928
Enhanced interleukin-16-CD4 signaling in CD3 T cell mediates neuropathic pain via activating astrocytes in female mice., PMID:39137872
Network pharmacology, molecular simulation, and binding free energy calculation-based investigation of Neosetophomone B revealed key targets for the treatment of cancer., PMID:38434705
Epigenome-wide methylation and progression to high-grade cervical intraepithelial neoplasia (CIN2+): a prospective cohort study in the United States., PMID:37932662
RNA N6-methyladenosine modification-based biomarkers for absorbed ionizing radiation dose estimation., PMID:37903783
Fgf22 and Fgfr2b are required for neurogenesis and gliogenesis in the zebrafish forebrain., PMID:37783119
Genome-wide identification and evolutionary analysis of the FGF gene family in buffalo., PMID:37697717
NR5A2 as a potential target for exercise to improve metabolic syndrome., PMID:37053002
Synaptogenic gene therapy with FGF22 improves circuit plasticity and functional recovery following spinal cord injury., PMID:36601738
Systematic analysis of expression profiles and prognostic significance of the FGF gene family in pancreatic adenocarcinoma., PMID:36311692
FGFRL1 and FGF genes are associated with height, hypertension, and osteoporosis., PMID:35980984
Pyruvate Upregulates Hepatic FGF21 Expression by Activating PDE and Inhibiting cAMP-Epac-CREB Signaling Pathway., PMID:35628302
Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1., PMID:34314389
FGFBP1-mediated crosstalk between fibroblasts and pancreatic cancer cells via FGF22/FGFR2 promotes invasion and metastasis of pancreatic cancer., PMID:34117747
Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement., PMID:34044102
Gene expression profiling of giant fibroadenomas of the breast., PMID:33677364
FGF22 promotes generation of ribbon synapses through downregulating MEF2D., PMID:32271716
Fibroblast Growth Factor 22 Inhibits ER Stress-Induced Apoptosis and Improves Recovery of Spinal Cord Injury., PMID:32116697
Neuronal fibroblast growth factor 22 signaling during development, but not in adults, is involved in anhedonia., PMID:31895747
Reduced Oxidative Stress and Enhanced FGF21 Formation in Livers of Endurance-Exercised Rats with Diet-Induced NASH., PMID:31717358
The Role of Fgf Signaling on Epithelial Cell Differentiation in Mouse Vagina., PMID:31471398
Carbohydrate Availability as a Regulator of Energy Balance With Exercise., PMID:31082986
ROS control in human iPS cells reveals early events in spontaneous carcinogenesis., PMID:31058919
An OMICS-based study of the role of C3dg in keratinocytes: RNA sequencing, antibody-chip array, and bioinformatics approaches., PMID:30974145
Integrated Analysis of Transcriptome and Prognosis Data Identifies FGF22 as a Prognostic Marker of Lung Adenocarcinoma., PMID:30803369
Endocrine Regulator rFGF21 (Recombinant Human Fibroblast Growth Factor 21) Improves Neurological Outcomes Following Focal Ischemic Stroke of Type 2 Diabetes Mellitus Male Mice., PMID:30571410
Expression of fibroblast growth factor 22 (FGF22) and its receptor, FGFR1B, during development and regression of bovine corpus luteum., PMID:30366151
Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium., PMID:29988085
Fibroblast growth factor 21, adiposity, and macronutrient balance in a healthy, pregnant population with overweight and obesity., PMID:29768065
Highly efficient production of functional recombinant human fibroblast growth factor 22 in E. coli and its protective effects on H2O2-lesioned L02 cells., PMID:29627393
FGF21 is induced in cisplatin nephrotoxicity to protect against kidney tubular cell injury., PMID:29401620
The Role of Autophagy in Critical Illness-induced Liver Damage., PMID:29074879
The role of suppression of hepatic SCD1 expression in the metabolic effects of dietary methionine restriction., PMID:28982014
Fibroblast growth factor 22 is a novel modulator of depression through interleukin-1β., PMID:28948716
Modifying the Dietary Carbohydrate-to-Protein Ratio Alters the Postprandial Macronutrient Oxidation Pattern in Liver of AMPK-Deficient Mice., PMID:28747486
Analysis of the FGF gene family provides insights into aquatic adaptation in cetaceans., PMID:28074842
Postsynaptic SDC2 induces transsynaptic signaling via FGF22 for bidirectional synaptic formation., PMID:27627962
Chondroitinase administration and pcDNA3.1-BDNF-BMSC transplantation promote motor functional recovery associated with NGF expression in spinal cord-transected rat., PMID:27349609
Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain., PMID:27083047
Deletion of fibroblast growth factor 22 (FGF22) causes a depression-like phenotype in adult mice., PMID:27036645
FGFR Inhibitor Ameliorates Hypophosphatemia and Impaired Engrailed-1/Wnt Signaling in FGF2 High Molecular Weight Isoform Transgenic Mice., PMID:26762209
Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 (FGF21) in aging mice., PMID:26697751
FGF22 protects hearing function from gentamycin ototoxicity by maintaining ribbon synapse number., PMID:26639016
Targeting neurotrophic factors and their receptors, but not cholinesterase or neurotransmitter, in the neurotoxicity of TDCPP in Chinese rare minnow adults (Gobiocypris rarus)., PMID:26552522
Presynaptic size of associational/commissural CA3 synapses is controlled by fibroblast growth factor 22 in adult mice., PMID:26222899
Evidence that fibroblast growth factor 10 plays a role in follicle selection in cattle., PMID:26194863
For research use only. Not for human or drug use.
