Catalog No.
YHJ51801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn21-Gly111
Predicted molecular weight
36.85 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BYW3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C20orf8, Epididymal secretory protein 13.2, DEFB26, Beta-defensin 26, Beta-defensin 126, DEFB126, HBD26, ESP13.2, DEFB-26, Defensin, beta 126
Beta-defensin 126 (DEFB126) localization and expression in the sperms and male reproductive tract of the dromedary camel (Camelus dromedarius) during the rutting season., PMID:40276191
DEFB126 2-nt Deletion (rs11467417) as a Potential Risk Factor for Chlamydia Trachomatis Infection and Subsequent Infertility in Iranian Men., PMID:39157277
Genetic Features of Tongue Cancer Recurrence in Young Adults., PMID:39127975
Construction of an immune-related gene signature for overall survival prediction and immune infiltration in gastric cancer., PMID:38577455
DEFB126 polymorphisms and association with idiopathic asthenozoospermia in China., PMID:35381696
Comparative RNA-Seq Analysis of Differentially Expressed Genes in the Epididymides of Yak and Cattleyak., PMID:32030088
Unusual interplay of contrasting selective pressures on β-defensin genes implicated in male fertility of the Buffalo (Bubalus bubalis)., PMID:31771505
Bacterial Virus Lambda Gpd-Fusions to Cathelicidins, α- and β-Defensins, and Disease-Specific Epitopes Evaluated for Antimicrobial Toxicity and Ability to Support Phage Display., PMID:31533281
Beta-defensin126 is correlated with sperm motility in fertile and infertile men†., PMID:31504198
The role of DEFB126 variation in male infertility and medically assisted reproduction technique outcome., PMID:31474436
Exome sequencing in Thai patients with familial obesity., PMID:27421018
Lectin binding of human sperm associates with DEFB126 mutation and serves as a potential biomarker for subfertility., PMID:26832966
Another functional frame-shift polymorphism of DEFB126 (rs11467497) associated with male infertility., PMID:25721098
Human beta-defensin DEFB126 is capable of inhibiting LPS-mediated inflammation., PMID:23229569
1.15 Mb microdeletion in chromosome band 20p13 associated with moderate developmental delay-additional case and data's review., PMID:23165892
Polymorphisms in pattern-recognition genes in the innate immunity system and risk of non-Hodgkin lymphoma., PMID:23055202
Multifunctional glycoprotein DEFB126--a curious story of defensin-clad spermatozoa., PMID:22710670
HE4 in ovarian cancer: from discovery to clinical application., PMID:22126021
Comparison of different ovarian cancer detection algorithms., PMID:21941963
Comparison of serum human epididymis protein 4 with cancer antigen 125 as a tumor marker in patients with malignant and nonmalignant diseases., PMID:21933899
Potential role of HE4 in multimodal screening for epithelial ovarian cancer., PMID:21917606
Integration of cell phone imaging with microchip ELISA to detect ovarian cancer HE4 biomarker in urine at the point-of-care., PMID:21881677
HE4 a novel tumour marker for ovarian cancer: comparison with CA 125 and ROMA algorithm in patients with gynaecological diseases., PMID:21863264
Evaluation of the diagnostic accuracy of the risk of ovarian malignancy algorithm in women with a pelvic mass., PMID:21775843
A common mutation in the defensin DEFB126 causes impaired sperm function and subfertility., PMID:21775668
Defending male fertility., PMID:21775666
Human epididymis protein 4 offers superior specificity in the differentiation of benign and malignant adnexal masses in premenopausal women., PMID:21722869
Utility of tumor marker HE4 to predict depth of myometrial invasion in endometrioid adenocarcinoma of the uterus., PMID:21720250
Human epididymis protein 4 (HE4) as a serum tumor biomarker in patients with ovarian carcinoma., PMID:21633297
HE4 and epithelial ovarian cancer: comparison and clinical evaluation of two immunoassays and a combination algorithm., PMID:21557935
Diagnostic performances of HE4 and CA125 for the detection of ovarian cancer from patients with various gynecologic and non-gynecologic diseases., PMID:21549107
Diagnostic and prognostic impact of serum HE4 detection in endometrial carcinoma patients., PMID:21468050
No benefit from combining HE4 and CA125 as ovarian tumor markers in a clinical setting., PMID:21420727
Evaluation of the accuracy of serum human epididymis protein 4 in combination with CA125 for detecting ovarian cancer: a prospective case-control study in a Korean population., PMID:21320028
HE4 and CA125 as a diagnostic test in ovarian cancer: prospective validation of the Risk of Ovarian Malignancy Algorithm., PMID:21304524
The ROMA (Risk of Ovarian Malignancy Algorithm) for estimating the risk of epithelial ovarian cancer in women presenting with pelvic mass: is it really useful?, PMID:21288178
Human epydidimis protein 4 (HE4): could it be useful in the diagnosis of vulvar cancer?, PMID:21141448
HE4 expression can be associated with lymph node metastases and disease-free survival in breast cancer., PMID:21115941
Prognostic significance of HE4 expression in pulmonary adenocarcinoma., PMID:20953751
Progranulin is a potential prognostic biomarker in advanced epithelial ovarian cancers., PMID:20950846
HE4 and mesothelin: novel biomarkers of ovarian carcinoma in patients with pelvic masses., PMID:20593939
The dire need to develop a clinically validated screening method for the detection of early-stage ovarian cancer., PMID:20550476
Ovarian tumor marker HE4 is differently expressed during the phases of the menstrual cycle in healthy young women., PMID:20490961
[HE4, a novel marker for epithelial ovarian cancer: evaluation of analytical performances]., PMID:20478777
Comparison of a novel multiple marker assay vs the Risk of Malignancy Index for the prediction of epithelial ovarian cancer in patients with a pelvic mass., PMID:20471625
PGE2 decreases reactivity of human platelets by activating EP2 and EP4., PMID:20451959
Detection of the HE4 protein in urine as a biomarker for ovarian neoplasms., PMID:20381233
Development of a multimarker assay for early detection of ovarian cancer., PMID:20368574
A step forward for two-step screening for ovarian cancer., PMID:20368556
HE4: a new potential early biomarker for the recurrence of ovarian cancer., PMID:20358424
For research use only. Not for human or drug use.
