Catalog No.
EHJ41201
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Arg31-Gln163
Predicted molecular weight
19.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q96PD4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IL17F, Interleukin-17F, IL-17F, Cytokine ML-1
Adipose-Derived Mesenchymal Stromal/Stem Cells Reduce Inflammatory Responses and Partially Alleviate Skin Symptoms in Imiquimod-Induced Psoriasis-Like Dermatitis Model Mice., PMID:40500215
LL-37 and citrullinated-LL-37 modulate IL-17A/F-mediated responses and selectively suppress Lipocalin-2 in bronchial epithelial cells., PMID:40410820
Metabolic Characteristics and Cytokine Gene Polymorphisms as Potential Risk Factors for a Higher Liver Fibrosis Stage in MASLD Patients: A Hospital-Based Study., PMID:40332363
Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and TYK2 Inhibitors via IL10 Antagonism., PMID:40320905
Assessing the clinical progress of the bispecific nanobody sonelokimab., PMID:40297934
Psoriasis in Obese Adolescents with Diabetes-From Common Molecular Background to Vicious Circle of Metabolic Syndrome-Case Report and Review of Literature., PMID:40277935
Andrographolide sulfonate alleviates rheumatoid arthritis by inhibiting glycolysis-mediated activation of PI3K/AKT to restrain Th17 cell differentiation., PMID:40274350
Investigating the relationship between the IL-17 rs2275913, IL-17 rs763780, and the IL-6 rs1800795 genotypes in HIV-positive patients with COVID-19., PMID:40268781
IL-17 Ligand and Receptor Family Members Are Differentially Expressed by Keratinocyte Subpopulations and Modulate Their Differentiation and Inflammatory Phenotype., PMID:40243580
Sakuranetin modulates IL-17A-related inflammation and enhances skin barrier function in an imiquimod-induced psoriasis model., PMID:40209307
Inflammatory markers activation associated with vapor or smoke exposure in Wistar rats., PMID:40191199
Interleukin 17-producing C-C motif chemokine receptor 6 + conventional CD4+ T cells are arthritogenic in an animal model of spondyloarthritis., PMID:40163937
Transcriptional and cytokine signatures of Mycobacterium abscessus complex pulmonary disease during disease progression and treatment., PMID:40163531
Understanding psoriatic disease at single-cell resolution: an update., PMID:40160177
Development and optimization of human T-cell leukemia virus-specific antibody-dependent cell-mediated cytotoxicity (ADCC) assay directed to the envelope protein., PMID:40152593
Hyperuricemia Exacerbates Psoriatic Inflammation by Inducing M1 Macrophage Activation and Th1 Cell Differentiation., PMID:40129056
Small molecule interleukin (IL) 17A/A antagonists and antibodies blocking both IL17A/A and IL17A/F demonstrate equivalent degrees of efficacy in preclinical models of skin and joint inflammation., PMID:40127522
PCSK6 ablation in blood circulating cells increases atherosclerotic burden, but improves plaque stability by activating Th17-smooth muscle cell modulatory axis., PMID:40097084
Artesunate alleviated murine ulcerative colitis by regulating immune response through inhibiting endoplasmic reticulum stress., PMID:40079012
Bimekizumab in the Treatment of Axial Spondyloarthritis and Psoriatic Arthritis: A New Kid on the Block., PMID:40076933
STING Deficiency Promotes Th17-Like Tfh to Aggravate the Experimental Autoimmune Uveitis., PMID:40042874
Psoriasis harbors multiple pathogenic type 17 T-cell subsets: Selective modulation by risankizumab., PMID:39978685
Ruxolitinib synergizes with regulatory T cells to improve inflammation but has no added benefits in decreasing albuminuria in SLE., PMID:39975551
Bimekizumab for Hidradenitis Suppurativa: Pathophysiology and Promising Interventions., PMID:39946257
α-Synuclein orchestrates Th17 responses as antigen and adjuvant in Parkinson's disease., PMID:39934862
Ex Vivo and In Vitro Proteomic Approach to Elucidate the Relevance of IL-4 and IL-10 in Intervertebral Disc Pathophysiology., PMID:39931581
Bimekizumab for the treatment of moderate to severe psoriasis: a real-world experience over 52 weeks from two Italian dermatology clinics., PMID:39925216
Genetic Variants of the IL-23/IL-17 Axis and Its Association With Periodontal Disease: A Systematic Review., PMID:39887950
Interleukin-17: A pleiotropic cytokine implicated in inflammatory, infectious, and malignant disorders., PMID:39875232
Interleukin-17A and Interleukin-17F Gene Polymorphisms in Egyptian Patients with Chronic Hepatitis C and Hepatocellular Carcinoma., PMID:39873997
IL-17 family members exert an autocrine pro-inflammatory loop in CF respiratory epithelial cells ex vivo., PMID:39837005
Probiotic administration aggravates dextran sulfate sodium salt-induced inflammation and intestinal epithelium disruption in weaned pig., PMID:39819657
Exercise intensity and training alter the innate immune cell type and chromosomal origins of circulating cell-free DNA in humans., PMID:39805013
Long-term safety and efficacy of bimekizumab in axial spondyloarthritis: 2-year results from two phase 3 studies., PMID:39798135
Multifaceted roles of IL-17 in bone and tendon health., PMID:39756745
SARS-CoV-2 ORF8 drives osteoclastogenesis in preexisting immune-mediated inflammatory diseases., PMID:39704167
When recombinant proteins go wrong: The hidden pitfall of recombinant protein contamination., PMID:39675101
Comparative analysis of WC1.1+ and WC1.2+ γδ T cell subset responses from cattle naturally infected with Mycobacterium bovis to repeat stimulation with mycobacterial antigens., PMID:39666627
Long-term efficacy and safety of bimekizumab in real-world setting: a 52-week prospective study., PMID:39666087
Association of baseline cytokines with antibody concentrations after diphtheria-tetanus-acellular pertussis booster vaccination in Finnish children., PMID:39616006
Green tea polyphenol alleviates silica particle-induced lung injury by suppressing IL-17/NF-κB p65 signaling-driven inflammation., PMID:39550922
Gene expression profiling reveals host defense strategies for restricting Candida albicans invasion and gastritis to the limiting ridge of the murine stomach., PMID:39535200
The roles of interleukin (IL)-17A and IL-17F in hidradenitis suppurativa pathogenesis: evidence from human in vitro preclinical experiments and clinical samples., PMID:39531733
Amelioration of Systemic Amyloidosis by Blocking IL-17A and Not by IL-17F, and Arteriosclerosis by Blocking Both IL-17A and IL-17F in an Inflammatory Skin Mouse Model., PMID:39519167
Effectiveness of long-term bimekizumab treatment and predictive factors for responders in moderate-to-severe psoriasis: A 52-week real-world study., PMID:39498997
Correlation of changes in inflammatory and collagen biomarkers with durable guselkumab efficacy through 2 years in participants with active psoriatic arthritis: results from a phase III randomized controlled trial., PMID:39493888
Circulating IL-17F, but not IL-17A, is elevated in severe COVID-19 and leads to an ERK1/2 and p38 MAPK-dependent increase in ICAM-1 cell surface expression and neutrophil adhesion on endothelial cells., PMID:39493750
Rhythmic IL-17 production by γδ T cells maintains adipose de novo lipogenesis., PMID:39478228
Th17 and T Regulatory Cytokines in Serum, Lesional Skin, and Stimulated Peripheral Blood Mononuclear Cell Culture Supernatants from Type 1 Leprosy Reaction Patients., PMID:39471504
Bimekizumab-bkzx for the Treatment of Plaque Psoriasis: A Drug Review., PMID:39425925
For research use only. Not for human or drug use.
