Catalog No.
YHJ33201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr546-His736
Predicted molecular weight
24.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92786
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PROX1, Prospero homeobox protein 1, PROX-1, Homeobox prospero-like protein PROX1
Increased CSF drainage by non-invasive manipulation of cervical lymphatics., PMID:40468071
PROX1 is an early driver of lineage plasticity in prostate cancer., PMID:40454483
Prox1 Protein in Corneal Limbal Lymphatic Vessels Maintains Limbal Stem Cell Stemness and Regulates Corneal Injury Repair., PMID:40298888
Dental pulp lymphatic vessel dynamics during tooth development and pulp stimulation in rodents., PMID:40277146
Immunohistochemical investigation of the transcription factor PROX1 emphasizing on neuroendocrine neoplasms., PMID:40234276
Analysis of the (lymph-)angiogenic potential of regenerative scaffolds and the impact of adipose-derived mesenchymal stem cells., PMID:40178869
Inhibition of COX2 impairs angiogenesis and causes vascular defects in developing zebrafish embryos., PMID:40172030
PROX1: A Key Regulator of Hepatocyte Identity and Tumorigenesis., PMID:40163354
Locking the Fate: How PROX1 Represses Plasticity and Liver Cancer., PMID:40135273
Restoration of retinal regenerative potential of Müller glia by disrupting intercellular Prox1 transfer., PMID:40133314
Metabolic expression profiling analysis reveals pyruvate-mediated EPHB2 upregulation promotes lymphatic metastasis in head and neck squamous cell carcinomas., PMID:40075431
Genome-Wide Association Study Identifying a Novel Gene Related to a History of Febrile Convulsions in Patients With Focal Epilepsy., PMID:40065453
Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumorigenesis., PMID:39948437
Exosomal miR-224-3p promotes lymphangiogenesis and lymph node metastasis by targeting GSK3B in gastric cancer., PMID:39866224
ENDOTHELIAL PROX1 INDUCES BLOOD-BRAIN BARRIER DISRUPTION IN THE CENTRAL NERVOUS SYSTEM., PMID:39803470
The Transcription Factor SOX18 Inhibitor Small Molecule 4 Is a Potential Treatment of Cancer-Induced Lymphatic Metastasis and Lymphangiosarcoma., PMID:39791369
Protective role of Pannexin1 in lymphatic endothelial cells in the progression of atherosclerosis in female mice., PMID:39775604
Upregulation of ABLIM1 Differentiates Intrahepatic Cholangiocarcinoma from Hepatocellular Carcinoma and Both Colorectal and Pancreatic Adenocarcinoma Liver Metastases., PMID:39766812
Identification and Validation of Epithelial Cell Centre Regulatory Transcription Factors in the Gastric Cancer Microenvironment., PMID:39759895
Direct specification of lymphatic endothelium from mesenchymal progenitors., PMID:39747454
The role of exercise in promoting lymphangiogenesis and extracellular matrix synthesis in lymphedema-induced tissue injury., PMID:39676093
Lymphovascular Tumoral Emboli in Inflammatory Breast Cancer Result from Haptotaxis-Mediated Encircling Lymphangiogenesis., PMID:39669476
Engineering ADSCs by manipulating YAP for lymphedema treatment in a mouse tail model., PMID:39633684
Molecules That Have Rarely Been Studied in Lymphatic Endothelial Cells., PMID:39596293
Proangiogenic effect of thyrotropin receptor stimulating antibody in human umbilical vein endothelial cells., PMID:39455509
Prox1a promotes liver growth and differentiation by repressing cdx1b expression and intestinal fate transition in zebrafish., PMID:39343095
Differentiation stage-specific expression of transcriptional regulators for epithelial mesenchymal transition in dentate granule progenitors., PMID:39268037
ERRα and ERRγ coordinate expression of genes associated with Alzheimer's disease, inhibiting DKK1 to suppress tau phosphorylation., PMID:39231208
Robust Differentiation of Human Pluripotent Stem Cells into Lymphatic Endothelial Cells Using Transcription Factors., PMID:39197437
Molecular expression of Forkhead Box C2 gene (FOXC2) and Prospero homeobox gene (PROX-1) in oral squamous carcinoma and their correlation with clinicopathological parameters: A prospective cohort study., PMID:39157851
Pannexin1 deletion in lymphatic endothelium affects lymphatic function in a sex-dependent manner., PMID:39085909
PROX1 is a regulator of neuroendocrine-related gene expression in lung carcinoid., PMID:39066858
FOXC1 and FOXC2 Ablation Causes Abnormal Valvular Endothelial Cell Junctions and Lymphatic Vessel Formation in Myxomatous Mitral Valve Degeneration., PMID:38989578
ERG Regulates Lymphatic Vessel Specification Genes and Its Deficiency Impairs Wound Healing-Associated Lymphangiogenesis., PMID:38965683
Fluid-Dynamic Modeling of Flow in Embryonic Tissue Indicates That Lymphatic Valve Location Is Not Consistently Determined by the Local Fluid Shear or Its Gradient., PMID:38953384
PROX1 drives neuroendocrine plasticity and liver metastases in prostate cancer., PMID:38901665
Memory loss and aberrant neurogenesis in mice exposed to patient anti-N-methyl-d-aspartate receptor antibodies., PMID:38801989
LECs regulate neutrophil clearance through IL-17RC/CMTM4/NF-κB axis at sites of inflammation or infection., PMID:38754839
Lymphatic endothelial cell-specific NRAS p.Q61R mutant embryos show abnormal lymphatic vessel morphogenesis., PMID:38743908
Single-nucleus RNA transcriptome profiling reveals murine adipose tissue endothelial cell proliferation gene networks involved in obesity development., PMID:38729594
Multiple cis-regulatory elements control prox1a expression in distinct lymphatic vascular beds., PMID:38722096
Zmiz1 is a novel regulator of lymphatic endothelial cell gene expression and function., PMID:38718095
Impact of Prospero Homeobox-1 (PROX-1) οn the Oncogenic Phenotypes of Hepatocellular Carcinoma Cells., PMID:38670585
DGAT2 Plays a Crucial Role to Control ESRRA-PROX1 Transcriptional Network to Maintain Hepatic Mitochondrial Sustainability., PMID:38644620
Knockdown of PROX1 promotes milk fatty acid synthesis by targeting PPARGC1A in dairy goat mammary gland., PMID:38518943
Immunohistochemical Expression of Lymphatic Endothelial Markers in Blue Rubber Bleb Nevus Syndrome., PMID:38512910
Vitamin D accelerates the subdural hematoma clearance through improving the meningeal lymphatic vessel function., PMID:38294731
Prox1 Suppresses Proliferation and Drug Resistance of Retinoblastoma Cells via Targeting Notch1., PMID:38277016
Dysregulated lncRNAs regulate human umbilical cord mesenchymal stem cell differentiation into insulin-producing cells by forming a regulatory network with mRNAs., PMID:38273351
Profibrotic VEGFR3-Dependent Lymphatic Vessel Growth in Autoimmune Valvular Carditis., PMID:38269589
For research use only. Not for human or drug use.
