Research Grade Pascolizumab (DHC13501)

Catalog No.

DHC13501

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

Binetrakin, B-cell stimulatory factor 1, Pitrakinra, Lymphocyte stimulatory factor 1, IL-4, BSF-1, IL4, Interleukin-4

Concentration

2.15 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P05112

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

SB-240683, CAS: 331243-22-2

Clone ID

Pascolizumab

[Current and future approaches for the treatment of inflammatory diseases of inferior respiratory tract], PMID: 16970111

A Critical Evaluation of Anti-IL-13 and Anti-IL-4 Strategies in Severe Asthma, PMID: 27637004

Modulating Interleukins and their Receptors Interactions with Small Chemicals Using In Silico Approach for Asthma, PMID: 30068279

Preclinical efficacy and safety of pascolizumab (SB 240683): a humanized anti-interleukin-4 antibody with therapeutic potential in asthma, PMID: 12296858

Targeting IL-4 for the Treatment of Atopic Dermatitis, PMID: 33062619

Document Download

Research Grade Pascolizumab.pdf