Catalog No.
YHJ27101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala18-Pro202
Predicted molecular weight
22.49 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8TAD2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interleukin-27, IL-27, IL-17D, IL17D, Interleukin-17D
Functional characterization of IL-17D in chub mackerel (Scomber japonicus): expression profiles, immunomodulatory roles, and antiviral implications., PMID:40345274
Lipoprotein (a) integrates monocyte-mediated thrombosis and inflammation in atherosclerotic cardiovascular disease., PMID:40334781
Identification and Expression Analyses of IL-17/IL-17R Gene Family in Snakehead (Channa argus) Following Nocardia seriolae Infection., PMID:40149405
WNT11 Promotes immune evasion and resistance to Anti-PD-1 therapy in liver metastasis., PMID:39920102
Interleukin-17: A pleiotropic cytokine implicated in inflammatory, infectious, and malignant disorders., PMID:39875232
IL-17 family members exert an autocrine pro-inflammatory loop in CF respiratory epithelial cells ex vivo., PMID:39837005
Immune changes in pregnancy: associations with pre-existing conditions and obstetrical complications at the 20th gestational week-a prospective cohort study., PMID:39696496
Interleukin-17D accelerates atherosclerosis through promoting endothelial cells ferroptosis via CD93/miR-181a-5p/SLC7A11 signaling., PMID:39510035
Circulating IL-17F, but not IL-17A, is elevated in severe COVID-19 and leads to an ERK1/2 and p38 MAPK-dependent increase in ICAM-1 cell surface expression and neutrophil adhesion on endothelial cells., PMID:39493750
Xylanase enhances gut microbiota-derived butyrate to exert immune-protective effects in a histone deacetylase-dependent manner., PMID:39434145
Evolutionary Analysis of the Mammalian IL-17 Cytokine Family Suggests Conserved Roles in Female Fertility., PMID:39177066
Daily crowding stress has limited, yet detectable effects on skin and head kidney gene expression in surgically tagged atlantic salmon (Salmo salar)., PMID:39089638
Integrated Epigenetic and Transcriptomic Analysis Identifies Interleukin 17 DNA Methylation Signature of Malignant Peripheral Nerve Sheath Tumor Progression and Metastasis., PMID:38820476
Cytokines and chemokines involved in HLA-B27-positive ankylosing spondylitis-associated acute anterior uveitis., PMID:38577559
Similar immune responses to alpha1-oleate and Bacillus Calmette-Guérin treatment in patients with bladder cancer., PMID:38553868
Th17/IL-17A axis is critical for pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc): SSc patients with high levels of serum IL-17A exhibit reduced lung functions and increased prevalence of PAH., PMID:38354516
Carrot Juice Intake Affects the Cytokine and Chemokine Response in Human Blood after Ex Vivo Lipopolysaccharide-Induced Inflammation., PMID:38068860
Clinical characteristics and prognosis of patients with heart failure and high concentrations of interleukin-17D., PMID:37739044
Interleukin-17D produced by alveolar epithelial type II cells alleviates LPS-induced acute lung injury via the Nrf2 pathway., PMID:37708335
Synergistic Effect of Treatment with Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus and Lipopolysaccharide on the Inflammatory Response of Porcine Pulmonary Microvascular Endothelial Cells., PMID:37515210
Associations of plasma proteomics with type 2 diabetes and related traits: results from the longitudinal KORA S4/F4/FF4 Study., PMID:37308750
Revisiting the interleukin 17 family of cytokines in psoriasis: pathogenesis and potential targets for innovative therapies., PMID:37283755
Blood-Based Proteomic Profiling Identifies Potential Biomarker Candidates and Pathogenic Pathways in Dementia., PMID:37175824
Novel insights into the cytokine network of rainbow trout Oncorhynchus mykiss using cell lines and primary leukocyte populations., PMID:37084856
ROS-activated MAPK/ERK pathway regulates crosstalk between Nrf2 and Hif-1α to promote IL-17D expression protecting the intestinal epithelial barrier under hyperoxia., PMID:36736221
IL-17D affects the chemokines and chemokine receptors of intestinal epithelial cells under hyperoxia., PMID:36461593
Comprehensive evaluation of breast cancer immunotherapy and tumor microenvironment characterization based on interleukin genes-related risk model., PMID:36443508
PI3Kγ controls IL-17A expression and attenuates alveolar bone loss in an experimental periodontitis model., PMID:36333479
IL-17D-induced inhibition of DDX5 expression in keratinocytes amplifies IL-36R-mediated skin inflammation., PMID:36271146
Network analysis between neuron dysfunction and neuroimmune response based on neural single-cell transcriptome of COVID-19 patients., PMID:36137317
Methionine played a positive role in improving the intestinal digestion capacity, anti-inflammatory reaction and oxidation resistance of grass carp, Ctenopharyngodon idella, fry., PMID:35940539
Interleukin-17D promotes lung cancer progression by inducing tumor-associated macrophage infiltration via the p38 MAPK signaling pathway., PMID:35939336
IL22RA1/JAK/STAT Signaling Acts As a Cancer Target Through Pan-Cancer Analysis., PMID:35874683
Evaluating immune response and metabolic related biomarkers pre-allogenic hematopoietic stem cell transplant in acute myeloid leukemia., PMID:35700185
Molecular cloning, expression analysis of interleukin 17D (cysteine knot cytokine) from Amphiprion clarkii and their functional characterization and NFκB pathway activation using FHM cells., PMID:35636699
Novel Insight Into Nutritional Regulation in Enhancement of Immune Status and Mediation of Inflammation Dynamics Integrated Study In Vivo and In Vitro of Teleost Grass Carp (Ctenopharyngodon idella): Administration of Threonine., PMID:35359991
Periodontal Disease Augments Cardiovascular Disease Risk Biomarkers in Rheumatoid Arthritis., PMID:35327515
Human transcriptomic response to periprosthetic joint infection., PMID:35306116
Gene expression profiles and pathway enrichment analysis to identification of differentially expressed gene and signaling pathways in epithelial ovarian cancer based on high-throughput RNA-seq data., PMID:34839022
Immunogenomic Landscape Analysis of Prognostic Immune-Related Genes in Hepatocellular Carcinoma., PMID:34745496
The apoptosis of grass carp (Ctenopharyngodon idella) muscle during postmortem condition regulated by the cytokines via TOR and NF-κB signaling pathways., PMID:34455325
ITLN1 inhibits tumor neovascularization and myeloid derived suppressor cells accumulation in colorectal carcinoma., PMID:34363021
From Messengers to Receptors in Psoriasis: The Role of IL-17RA in Disease and Treatment., PMID:34201664
[γδ1 T cells derived from breast cancer tissue induce immunosenescence of naive CD4+ T cells by producing IL-17D]., PMID:34140074
Nuclear factor erythroid 2-related factor 2 potentiates the generation of inflammatory cytokines by intestinal epithelial cells during hyperoxia by inducing the expression of interleukin 17D., PMID:34023435
Out of the shadow of interleukin-17A: the role of interleukin-17F and other interleukin-17 family cytokines in spondyloarthritis., PMID:34001692
Interleukin-17D regulates group 3 innate lymphoid cell function through its receptor CD93., PMID:33852831
In-Depth Analysis of the Hidradenitis Suppurativa Serum Proteome Identifies Distinct Inflammatory Subtypes., PMID:33766512
Keep Garfagnina alive. An integrated study on patterns of homozygosity, genomic inbreeding, admixture and breed traceability of the Italian Garfagnina goat breed., PMID:33449925
Much More Than IL-17A: Cytokines of the IL-17 Family Between Microbiota and Cancer., PMID:33244315
For research use only. Not for human or drug use.
