Catalog No.
YHJ06101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr336-Arg455
Predicted molecular weight
15.87 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6KF10
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BMP-13, BMP13, GDF6, Growth/differentiation factor 6, GDF16, Growth/differentiation factor 16, GDF-6, Bone morphogenetic protein 13
Proliferative arrest induces neuronal differentiation and innate immune responses in normal and Creutzfeldt-Jakob Disease agent (CJ) infected rat septal neurons., PMID:40434970
Effects of GDF6 on active protein synthesis by cells of degenerated intervertebral disc., PMID:39920317
Therapeutic potential and mechanisms of umbilical cord mesenchymal stem cells differentiating into tendon cells and promotion of rotator cuff tendon-bone healing., PMID:39882545
Therapeutic Effects of GDF6-Overexpressing Mesenchymal Stem Cells through Upregulation of the GDF15/SIRT1 Axis in Age-Related Hearing Loss., PMID:39862101
The master male sex determinant Gdf6Y of the turquoise killifish arose through allelic neofunctionalization., PMID:39788971
The GDF6-FTO axis modulates the innate immune and inflammatory response to human respiratory syncytial virus., PMID:39474078
Construction and validation of a comprehensive metabolism-associated prognostic model for predicting survival and immunotherapy benefits in ovarian cancer., PMID:39440060
Proliferative arrest induces neuronal differentiation and innate immune responses in normal and Creutzfeldt-Jakob Disease agent (CJ) infected rat septal neurons., PMID:39131355
[Advances in genetic research on Non-syndromic congenital joint synostosis]., PMID:39097287
GDF6 in gastric cancer upregulated by helicobacter pylori induces epithelial-mesenchymal translation via the TGF-β/SMAD3 signaling pathway., PMID:38850874
Transforming growth factor-β (TGF-β): A master signal pathway in teleost sex determination., PMID:38821217
Genetic insights into the 'sandwich fusion' subtype of Klippel-Feil syndrome: novel FGFR2 mutations identified by 21 cases of whole-exome sequencing., PMID:38561822
The PIEZO1/miR-155-5p/GDF6/SMAD2/3 signaling axis is involved in inducing the occurrence and progression of osteoarthritis under excessive mechanical stress., PMID:38508350
A novel DNA methylation signature revealed GDF6 and RCC1 as potential prognostic biomarkers correlated with cell proliferation in clear cell renal cell carcinoma., PMID:38087057
Exosomal miRNA-155-5p from M1-polarized macrophages suppresses angiogenesis by targeting GDF6 to interrupt diabetic wound healing., PMID:38074896
Transcriptome profiling reveals transcriptional regulation of Protegrin-1 on immune defense and development in porcine granulosa cells., PMID:37741593
Gonadal transcriptome analysis of paradise fish Macropodus opercularis to reveal sex-related genes., PMID:37666127
METTL3 enhances dentinogenesis differentiation of dental pulp stem cells via increasing GDF6 and STC1 mRNA stability., PMID:37041485
Characterization of Histone Modifications in Late-Stage Rotator Cuff Tendinopathy., PMID:36833423
Identification and profiling of microRNAs during yak's testicular development., PMID:36803968
Defective Joint Development and Maintenance in GDF6-Related Multiple Synostoses Syndrome., PMID:36744814
Transcriptional Interference Regulates the Evolutionary Development of Speech., PMID:35885978
Potential Biomarkers and Drugs for Nanoparticle-Induced Cytotoxicity in the Retina: Based on Regulation of Inflammatory and Apoptotic Genes., PMID:35565057
Bone morphogenetic protein 13 in hepatic stellate cells and hepatic fibrosis., PMID:35442524
Protective Effects of Growth Differentiation Factor-6 on the Intervertebral Disc: An In Vitro and In Vivo Study., PMID:35406739
Novel FGF9 variant contributes to multiple synostoses syndrome 3., PMID:35316564
Preoperative Serum Calcitonin Level and Ultrasonographic Characteristics Predict the Risk of Metastatic Medullary Thyroid Carcinoma: Functional Analysis of Calcitonin-Related Genes., PMID:35280443
Nonwoven-based gelatin/polycaprolactone membrane loaded with ERK inhibitor U0126 for treatment of tendon defects., PMID:35012661
Global Histone H3 Lysine 4 Trimethylation (H3K4me3) Landscape Changes in Response to TGFβ., PMID:34671716
GDF6 Knockdown in a Family with Multiple Synostosis Syndrome and Speech Impairment., PMID:34573339
siRNA Mediate RNA Interference Concordant with Early On-Target Transient Transcriptional Interference., PMID:34440463
A Novel Human Long Noncoding RNA SCDAL Promotes Angiogenesis through SNF5-Mediated GDF6 Expression., PMID:34319658
Evolution of master sex determiners: TGF-β signalling pathways at regulatory crossroads., PMID:34247498
Differentiation of human adipose-derived mesenchymal stem cells toward tenocyte by platelet-derived growth factor-BB and growth differentiation factor-6., PMID:34013429
Skeletal Muscle Transcriptome Analysis of Hanzhong Ma Duck at Different Growth Stages Using RNA-Seq., PMID:33669581
[Clinical Characteristics and Genetic Analysis of Klippel-Feil Syndrome]., PMID:33663658
Non-viral Gene Delivery Methods for Bone and Joints., PMID:33330428
GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth., PMID:33147457
Identification of the third FGF9 variant in a girl with multiple synostosis-comparison of the genotype:phenotype of FGF9 variants in humans and mice., PMID:33140402
Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)-Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells., PMID:33054395
Regenerative Response of Degenerate Human Nucleus Pulposus Cells to GDF6 Stimulation., PMID:32992671
Induction of tenogenic differentiation of equine adipose-derived mesenchymal stem cells by platelet-derived growth factor-BB and growth differentiation factor-6., PMID:32875433
Rare heterozygous GDF6 variants in patients with renal anomalies., PMID:32737436
Transcriptomic and proteomic analyses of ovarian follicles reveal the role of VLDLR in chicken follicle selection., PMID:32677893
Growth differentiation factor-6 attenuates inflammatory and pain-related factors and degenerated disc-induced pain behaviors in rat model., PMID:32617997
High BMPR2 expression leads to enhanced SMAD1/5/8 signalling and GDF6 responsiveness in human adipose-derived stem cells: implications for stem cell therapies for intervertebral disc degeneration., PMID:32489577
Application of Multiplex Bisulfite PCR-Ligase Detection Reaction-Real-Time Quantitative PCR Assay in Interrogating Bioinformatically Identified, Blood-Based Methylation Markers for Colorectal Cancer., PMID:32407802
Long-range cis-regulatory elements controlling GDF6 expression are essential for ear development., PMID:32369452
Abnormal Cone and Rod Photoreceptor Morphogenesis in gdf6a Mutant Zebrafish., PMID:32293666
For research use only. Not for human or drug use.
