Catalog No.
YHH25001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met17-Asn605
Predicted molecular weight
68.39 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16236
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NFE2-related factor 2, Nuclear factor, erythroid derived 2, like 2, NRF2, Nuclear factor erythroid 2-related factor 2, NFE2L2, Nrf-2, HEBP1, NF-E2-related factor 2
Lachnospiraceae bacterium alleviates alcohol-associated liver disease by enhancing N-acetyl-glutamic acid levels and inhibiting ferroptosis through the KEAP1-NRF2 pathway., PMID:40511521
AS-IV Attenuates Oxidative Stress-Induced Apoptosis in Zebrafish via Modulation of the AKT/NRF2/HO-1/Caspase-3 Signaling Axis., PMID:40509241
Suk-SaiYasna Remedy, a Traditional Thai Medicine, Mitigates Stress-Induced Cognitive Impairment via Keap1-Nrf2 Pathway., PMID:40508195
Polygonum multiflorum Inhibits Pulmonary Inflammation and Fibrosis in PM2.5-Induced Dysfunction Through the Regulation of the TLR4/TGF-β1 Signaling Pathway in Mice., PMID:40507891
Fisetin Attenuates Zinc Overload-Induced Hepatotoxicity in Mice via Autophagy-Dependent Nrf2 Activation., PMID:40507790
Inhibition of Ferroptosis Attenuates Neuron Damage and Improves Cognitive Impairment in Mice Surviving Severe Hypothermia., PMID:40507777
Mechanism study of naringenin in treating sepsis-induced kidney injury based on network pharmacology., PMID:40501235
Dietary supplementation of Lactobacillus casei alleviates permethrin exposure-induced zebrafish testis damage through modulation of TLR4/NF-κB and AKT/Nrf2 pathways: Oxidative stress, inflammation and ferroptosis., PMID:40500058
Impact of grape seed proanthocyanidin B2 pretreatment on mitochondrial oxidative stress, endoplasmic reticulum stress, and apoptosis in renal tubular epithelial cells during in-vitro hypoxia-reoxygenation., PMID:40498953
Erianin Protects Human Umbilical Vein Endothelial Cells From Oxidized Low-Density Lipoprotein-Induced Apoptosis and Oxidative Stress Through Activation of Nuclear Factor E2-Related Factor 2 Signaling., PMID:40490908
EZH1 deficiency promotes ferroptosis resistance by activating NRF2 in sepsis-associated liver injury., PMID:40490833
Mechanistic evaluation of a traditional herbal decoction in attenuating hepatic fibrosis via Nrf2/GPX4 pathway activation and ferroptosis inhibition., PMID:40490825
Loss of ARNTL Enhances ER Stress and Apoptosis in CKD Through Disruption of NRF2 Signaling., PMID:40489010
CD44 Deficiency Induces Combinatory NRF2 Inhibition and Endoplasmic Reticulum Stress-Associated Dyserythropoiesis., PMID:40488748
Mechanism of fumonisin B1 on growth performance and intestinal structural integrity of juvenile grass carp (Ctenopharyngodon idella)., PMID:40487097
Empagliflozin ameliorates RSL3-induced ferroptosis in vascular endothelial cells via the NRF2/HO-1 pathway., PMID:40483457
Low-Dose Lipopolysaccharide Alleviates Neuronal Apoptosis and Oxidative Stress in Rats with Spinal Cord Injury by Inducing Nrf2 m6A Methylation Modification via Suppressing ALKBH5., PMID:40481942
Role and mechanism of lncRNA ZEB1-AS1 endogenous competition for miR-365a-3p targeting NRF2 in ferroptosis in articular chondrocytes., PMID:40481906
Cyanidin-3-glucoside phenolic metabolites, protocatechuic acid and vanillic acid, attenuate the adhesion of monocytes to endothelial cells in response to TNF-α by targeting NF-κB and Nrf2 pathways., PMID:40481863
Oxidative stress activates the transplanted adipose-derived stem cells to exert antioxidant effects in alopecia treatment., PMID:40479645
Human umbilical cord mesenchymal stem cell-derived exosomes mitigate acute radiation-induced intestinal oxidative damage via the Nrf2/HO-1/NQO1 signaling pathway., PMID:40478886
Kaempferol inhibits oxidative stress and reduces macrophage pyroptosis by activating the NRF2 signaling pathway., PMID:40478791
Glutathione peroxidase 3 antagonizes oxidative stress and inflammation in diabetic retinopathy via NrF2/NF-κB pathway., PMID:40478328
Research progress on Nrf2 intervention in the treatment of diabetic retinopathy., PMID:40469432
Hypoxia-inducible factor-1 alpha and nuclear factor erythroid 2-related factor 2 as biomarkers of renal scarring in children with congenital anomalies of the kidney and urinary tract: a prospective case-control study., PMID:40468229
Study on the Effect of Naringenin on LPS-Induced Acute Lung Injury Based on NRF2/HO-1 Pathway., PMID:40465481
[FGF19 alleviates inflammatory injury in vascular endothelial cells by activating the Nrf2/HO-1 signaling pathway]., PMID:40462435
Exploring the Effect and Mechanism of Liraglutide in Treating Depression Based on Network Pharmacology and Experimental Analysis., PMID:40461955
Cuproptosis-related gene signatures define the immune microenvironment in diabetic nephropathy., PMID:40460381
Hepatic ferroptosis induced by Clonorchis sinensis exacerbates liver fibrosis., PMID:40455823
Alpinetin protects against iron overload related osteoarthritis via NRF2/HO-1 pathway., PMID:40455747
Perinatal nicotine-induced neurotoxicity and behavioral alterations in newborn mice are associated with oxidative stress, inflammation and downregulated Nrf2/HO-1 signaling: protective role of Anethum graveolens., PMID:40455124
Gintonin enhances epithelial barrier function by activating NRF2 pathway in radiation-induced intestinal injury., PMID:40453351
A Novel Flavonoid Derivative of Icariside II (YS-10) Improves Erectile Dysfunction in a Diabetic Rat Model by Inhibiting Ferroptosis via Activation of the Nrf2/HO-1/GPX4 Pathway., PMID:40453214
Ameliorative Effects of the Neng-Jing-Huo Essential Oil Blend on H2O2-induced Oxidative Stress Injury in NRK-52E Cells via the AMPK/Nrf2/HO-1 Signaling Pathway., PMID:40451821
Melatonin modulates mitochondrial function and inhibits atherosclerosis progression through NRF2 activation and OPA1 inhibition., PMID:40449269
The Single and Combined Effects of Decabromodiphenyl Ethane and Mixed Microplastics on Male Mice Reproductive Toxicity., PMID:40448585
Gastrodia elata polysaccharide alleviates depression via gut microbiota modulation and Keap1-Nrf2/BDNF-TrkB pathway activation., PMID:40447013
Lutein: A natural defence combating age-related macular degeneration., PMID:40446575
NAD+/Nrf2 signaling promotes osteogenesis by regulating oxidative level of BMSCs under mechanical stress., PMID:40445451
Hepatoprotective Effect of Meroterpenoid-Rich Fraction from the Ethanolic Extract of Sargassum sarratifolium on tert-Butyl Hydroperoxide-Induced Mice., PMID:40443236
The role of HMOX1-mediated ferroptosis in blue light-induced damage to retinal pigment epithelium., PMID:40442370
Study of the ameliorative effect of β-Bisabolene on ischemic stroke via COX-2 with the Keap1/Nrf2 and MAPK pathways., PMID:40441590
RETREG1-mediated reticulophagy is activated by an ATF4-CEBPG/C/EBPγ heterodimer and confers protection against lipotoxicity., PMID:40437698
Marein from Coreopsis tinctoria Nutt. alleviates oxidative stress and lipid accumulation via SIRT1/Nrf2 signaling., PMID:40437103
Lacticaseibacillus paracasei NCU-21 improves ethanol-induced gastric mucosal injury by regulating the Nrf2/HO-1 signalling pathway and gastrointestinal microbiota in mice., PMID:40436552
Ginkgolide B inhibits ferroptosis in PC12 cells and ameliorates the oxidative stress in spinal cord injury through activating Nrf2 signaling pathway., PMID:40436481
Protective Effects of Panax notoginseng Saponins on Cerebral Ischemia/Reperfusion Injury: Insights Into SIRT1/NRF2/HO-1 Pathway Activation., PMID:40432445
Artemisiae Iwayomogii Herba Protects Dopaminergic Neurons Against 1-Methyl-4-phenylpyridinium/1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Neurotoxicity in Models of Parkinson's Disease., PMID:40431412
Protective Role of Whey Protein Isolate on MPP+-Induced Differentiation of SH-SY5Y Cells by Modulating the Nrf2 Antioxidant Pathway., PMID:40430379
For research use only. Not for human or drug use.
