Catalog No.
YHG84701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe240-Gly399
Predicted molecular weight
20.02 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q14623
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HHG-2, IHH, Indian hedgehog protein
Zic3 represses anterior digit development in tetrapods., PMID:40407133
FAM20B-Catalyzed Glycosylation Regulates the Chondrogenic and Osteogenic Differentiation of the Embryonic Condyle by Controlling IHH Diffusion and Release., PMID:40362273
Mechanism of action of IHH in ameliorating thin endometrium., PMID:40301068
A novel human hepatocyte cell line to study PNPLA3-associated steatotic liver disease., PMID:40266007
Mandibular Condylar Cartilage in Development and Diseases: A PTHrP-Centric View., PMID:40251915
German longevity study reveals novel rare pro-longevity alleles clustering in mTOR signaling pathway., PMID:40232348
miRNA-based regulation in growth plate cartilage: mechanisms, targets, and therapeutic potential., PMID:40225327
Gene proteins, growth factors/their receptors in the wall of chronic calculous cholecystitis-affected gallbladder children., PMID:40221697
Conformation-sensitive targeting of CD18 depletes M2-like tumor-associated macrophages resulting in inhibition of solid tumor progression., PMID:40187756
Effect of FcRn Binding on Monoclonal Antibody Disposition in the Brain., PMID:40169451
Neurokinin 3 receptor agonist senktide stimulates GnRH release in isolated hypogonadotropic hypogonadism mice., PMID:40135619
hsa_circ_0004846 enhances the malignant phenotype of papillary thyroid carcinoma cells via the miR‑142‑3p/PELI1 axis., PMID:40070794
A Novel Biallelic Variant in IHH Causing Acrocapitofemoral Dysplasia in a Pakistani Family., PMID:40045933
Cbfβ: A key regulator in skeletal stem cell differentiation, bone development, and disease., PMID:39996474
Utility of Optical Genome Mapping for Accurate Detection and Fine-Mapping of Structural Variants in Elusive Rare Diseases., PMID:39941010
Transcriptional factor ISL1 regulates palate development by tuning the SHH cascade., PMID:39704783
SEMA3C promotes thyroid cancer via the Wnt/β-catenin pathway., PMID:39667698
The Molecular Mechanism Investigation of HBP-A Slows Down Meniscus Hypertrophy and Mineralisation by the Damage Mechanical Model., PMID:39656450
Indian Hedgehog (IHh) Protein and COX-2 as Biomarkers to Define the Mechanism of Epilepsy and Gastrointestinal Problems as Comorbid Medical Illnesses in Autism Spectrum Disorder: Combining ROC Curves to Improve Diagnostic Values., PMID:39597837
Hedgehog Signalling Pathway and Its Role in Shaping the Architecture of Intestinal Epithelium., PMID:39596072
Serinc5 Regulates Sequential Chondrocyte Differentiation by Inhibiting Sox9 Function in Pre-Hypertrophic Chondrocytes., PMID:39568258
Timing of resting zone parathyroid hormone-related protein expression affects maintenance of the growth plate during secondary ossification: a computational study., PMID:39549120
IHH-GLI-1-HIF-2α signalling influences hypertrophic chondrocytes to exacerbate osteoarthritis progression., PMID:39498143
Downregulation of Krüppel-like factor 15 expression delays endochondral bone ossification during fracture healing., PMID:39437873
CARD9 promotes cholangiocarcinoma by regulating the IL-17A/Hedgehog and the THEM4/AKT/mTOR signaling pathways., PMID:39418733
Role of hedgehog signaling in the pathogenesis and therapy of heterotopic ossification., PMID:39364140
Bone development by Hedgehog and Wnt signaling, Runx2, and Sp7., PMID:39352550
A heterozygous SPRY4 variant identified in female infertility characterized by reduced oocyte potential and early embryonic arrest., PMID:39348320
Dissecting SOX9 dynamics reveals its differential regulation in osteoarthritis., PMID:39344191
Effects of intermittent exposure to hypobaric hypoxia and cold on skeletal muscle regeneration: Mitochondrial dynamics, protein oxidation and turnover., PMID:39313011
Expanding the Spectrum of Endocrine Abnormalities Associated With SOX11-related Disorders., PMID:39290158
Lack of a genetic risk continuum between pubertal timing in the general population and idiopathic hypogonadotropic hypogonadism., PMID:39256164
The G protein-coupled receptor ADGRG6 maintains mouse growth plate homeostasis through IHH signaling., PMID:39236220
Astragalus Extract Mixture HT042 Alleviates Dexamethasone-Induced Bone Growth Retardation in Rat Metatarsal Bones., PMID:39064775
Variety of genetic defects in GnRH and hypothalamic-pituitary signaling and development in normosmic patients with IHH., PMID:39010903
The Assessment of CDX1, IHH, SHH, GATA4, FOXA2, FOXF1 in Congenital Intra-Abdominal Adhesions., PMID:38978864
Variants in both the N- or C-terminal domains of IHH lead to defective secretion causing short stature and skeletal defects., PMID:38917024
A mathematical model of signalling molecule-mediated processes during regeneration of osteochondral defects after chondrocyte implantation., PMID:38908475
Genetic analysis of congenital unilateral renal agenesis in children based on next-generation sequencing., PMID:38849481
The role of GDF5 in regulating enthesopathy development in the Hyp mouse model of XLH., PMID:38836497
Low MBOAT7 expression, a genetic risk for MASH, promotes a profibrotic pathway involving hepatocyte TAZ upregulation., PMID:38776184
Ex vivo organotypic bone slice culture reveals preferential chondrogenesis after sustained growth plate injury., PMID:38740089
A Pilot Immunohistochemical Study Identifies Hedgehog Pathway Expression in Sinonasal Adenocarcinoma., PMID:38731849
Prominent Expression of COL2A1, ACAN and IHH Genes are Observed in the Differentiation of Human Hematopoietic Stem Cells into Articular Type of Chondrocytes., PMID:38635128
Key Roles of Gli1 and Ihh Signaling in Craniofacial Development., PMID:38623785
ERβ Regulation of Indian Hedgehog Expression in the First Wave of Ovarian Follicles., PMID:38607081
BMP7-induced osteoblast differentiation requires hedgehog signaling and involves nuclear mechanisms of gene expression control., PMID:38591759
Intra-articular injection of miRNA-1 agomir, a novel chemically modified miRNA agonists alleviates osteoarthritis (OA) progression by downregulating Indian hedgehog in rats., PMID:38582868
Mesenchymal stromal cell chondrogenesis under ALK1/2/3-specific BMP inhibition: a revision of the prohypertrophic signalling network concept., PMID:38581019
Leucine improves thiram-induced tibial dyschondroplasia and gut microbiota dysbiosis in broilers., PMID:38564867