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Recombinant Human IHH Protein, N-His

Catalog #:   YHG84701 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q14623
Protein length: Phe240-Gly399
Overview

Catalog No.

YHG84701

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Phe240-Gly399

Predicted molecular weight

20.02 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q14623

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

HHG-2, IHH, Indian hedgehog protein

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human IHH protein
References

Zic3 represses anterior digit development in tetrapods., PMID:40407133

FAM20B-Catalyzed Glycosylation Regulates the Chondrogenic and Osteogenic Differentiation of the Embryonic Condyle by Controlling IHH Diffusion and Release., PMID:40362273

Mechanism of action of IHH in ameliorating thin endometrium., PMID:40301068

A novel human hepatocyte cell line to study PNPLA3-associated steatotic liver disease., PMID:40266007

Mandibular Condylar Cartilage in Development and Diseases: A PTHrP-Centric View., PMID:40251915

German longevity study reveals novel rare pro-longevity alleles clustering in mTOR signaling pathway., PMID:40232348

miRNA-based regulation in growth plate cartilage: mechanisms, targets, and therapeutic potential., PMID:40225327

Gene proteins, growth factors/their receptors in the wall of chronic calculous cholecystitis-affected gallbladder children., PMID:40221697

Conformation-sensitive targeting of CD18 depletes M2-like tumor-associated macrophages resulting in inhibition of solid tumor progression., PMID:40187756

Effect of FcRn Binding on Monoclonal Antibody Disposition in the Brain., PMID:40169451

Neurokinin 3 receptor agonist senktide stimulates GnRH release in isolated hypogonadotropic hypogonadism mice., PMID:40135619

hsa_circ_0004846 enhances the malignant phenotype of papillary thyroid carcinoma cells via the miR‑142‑3p/PELI1 axis., PMID:40070794

A Novel Biallelic Variant in IHH Causing Acrocapitofemoral Dysplasia in a Pakistani Family., PMID:40045933

Cbfβ: A key regulator in skeletal stem cell differentiation, bone development, and disease., PMID:39996474

Utility of Optical Genome Mapping for Accurate Detection and Fine-Mapping of Structural Variants in Elusive Rare Diseases., PMID:39941010

Transcriptional factor ISL1 regulates palate development by tuning the SHH cascade., PMID:39704783

SEMA3C promotes thyroid cancer via the Wnt/β-catenin pathway., PMID:39667698

The Molecular Mechanism Investigation of HBP-A Slows Down Meniscus Hypertrophy and Mineralisation by the Damage Mechanical Model., PMID:39656450

Indian Hedgehog (IHh) Protein and COX-2 as Biomarkers to Define the Mechanism of Epilepsy and Gastrointestinal Problems as Comorbid Medical Illnesses in Autism Spectrum Disorder: Combining ROC Curves to Improve Diagnostic Values., PMID:39597837

Hedgehog Signalling Pathway and Its Role in Shaping the Architecture of Intestinal Epithelium., PMID:39596072

Serinc5 Regulates Sequential Chondrocyte Differentiation by Inhibiting Sox9 Function in Pre-Hypertrophic Chondrocytes., PMID:39568258

Timing of resting zone parathyroid hormone-related protein expression affects maintenance of the growth plate during secondary ossification: a computational study., PMID:39549120

IHH-GLI-1-HIF-2α signalling influences hypertrophic chondrocytes to exacerbate osteoarthritis progression., PMID:39498143

Downregulation of Krüppel-like factor 15 expression delays endochondral bone ossification during fracture healing., PMID:39437873

CARD9 promotes cholangiocarcinoma by regulating the IL-17A/Hedgehog and the THEM4/AKT/mTOR signaling pathways., PMID:39418733

Role of hedgehog signaling in the pathogenesis and therapy of heterotopic ossification., PMID:39364140

Bone development by Hedgehog and Wnt signaling, Runx2, and Sp7., PMID:39352550

A heterozygous SPRY4 variant identified in female infertility characterized by reduced oocyte potential and early embryonic arrest., PMID:39348320

Dissecting SOX9 dynamics reveals its differential regulation in osteoarthritis., PMID:39344191

Effects of intermittent exposure to hypobaric hypoxia and cold on skeletal muscle regeneration: Mitochondrial dynamics, protein oxidation and turnover., PMID:39313011

Expanding the Spectrum of Endocrine Abnormalities Associated With SOX11-related Disorders., PMID:39290158

Lack of a genetic risk continuum between pubertal timing in the general population and idiopathic hypogonadotropic hypogonadism., PMID:39256164

The G protein-coupled receptor ADGRG6 maintains mouse growth plate homeostasis through IHH signaling., PMID:39236220

Astragalus Extract Mixture HT042 Alleviates Dexamethasone-Induced Bone Growth Retardation in Rat Metatarsal Bones., PMID:39064775

Variety of genetic defects in GnRH and hypothalamic-pituitary signaling and development in normosmic patients with IHH., PMID:39010903

The Assessment of CDX1, IHH, SHH, GATA4, FOXA2, FOXF1 in Congenital Intra-Abdominal Adhesions., PMID:38978864

Variants in both the N- or C-terminal domains of IHH lead to defective secretion causing short stature and skeletal defects., PMID:38917024

A mathematical model of signalling molecule-mediated processes during regeneration of osteochondral defects after chondrocyte implantation., PMID:38908475

Genetic analysis of congenital unilateral renal agenesis in children based on next-generation sequencing., PMID:38849481

The role of GDF5 in regulating enthesopathy development in the Hyp mouse model of XLH., PMID:38836497

Low MBOAT7 expression, a genetic risk for MASH, promotes a profibrotic pathway involving hepatocyte TAZ upregulation., PMID:38776184

Ex vivo organotypic bone slice culture reveals preferential chondrogenesis after sustained growth plate injury., PMID:38740089

A Pilot Immunohistochemical Study Identifies Hedgehog Pathway Expression in Sinonasal Adenocarcinoma., PMID:38731849

Prominent Expression of COL2A1, ACAN and IHH Genes are Observed in the Differentiation of Human Hematopoietic Stem Cells into Articular Type of Chondrocytes., PMID:38635128

Key Roles of Gli1 and Ihh Signaling in Craniofacial Development., PMID:38623785

ERβ Regulation of Indian Hedgehog Expression in the First Wave of Ovarian Follicles., PMID:38607081

BMP7-induced osteoblast differentiation requires hedgehog signaling and involves nuclear mechanisms of gene expression control., PMID:38591759

Intra-articular injection of miRNA-1 agomir, a novel chemically modified miRNA agonists alleviates osteoarthritis (OA) progression by downregulating Indian hedgehog in rats., PMID:38582868

Mesenchymal stromal cell chondrogenesis under ALK1/2/3-specific BMP inhibition: a revision of the prohypertrophic signalling network concept., PMID:38581019

Leucine improves thiram-induced tibial dyschondroplasia and gut microbiota dysbiosis in broilers., PMID:38564867

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human IHH Protein, N-His [YHG84701]
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