Catalog No.
YHG10601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Cys98-Ala363
Predicted molecular weight
32.18 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q06889
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Early growth response protein 3, EGR-3, EGR3, Zinc finger protein pilot, PILOT
The EGR3 gene modulates CRP and VCAM-1 expression to promote the development of atherosclerosis., PMID:40513687
Multifaceted regulatory mechanisms of the EGR family in tumours and prospects for therapeutic applications (Review)., PMID:40444475
EGR3 deficiency alleviates cigarette smoke-induced pulmonary inflammation in COPD through TLR4/NF-κB/TIMP-1 axis., PMID:40220490
DYRK1A roles in human neural progenitors., PMID:40182141
Identification and validation of susceptibility modules and hub genes in polyarticular juvenile idiopathic arthritis using WGCNA and machine learning., PMID:39699225
Identification and validation of apoptosis-related genes in acute myocardial infarction based on integrated bioinformatics methods., PMID:39650552
A novel micropeptide miPEP205 suppresses the growth and metastasis of TNBC., PMID:39623077
flt1 inactivation promotes zebrafish cardiac regeneration by enhancing endothelial activity and limiting the fibrotic response., PMID:39612288
Molecular mechanism of IgE-mediated FcεRI activation., PMID:39442557
Immunoinhibitory effects of hypoxia-driven reprogramming of EGR1hi and EGR3 positive B cells in the nasopharyngeal carcinoma microenvironment., PMID:39197193
Early growth response factor 3 may regulate coronary atherosclerosis through the NF-κB signaling pathway and VEGF expression., PMID:38992750
EGR3 Inhibits Tumor Progression by Inducing Schwann Cell-Like Differentiation., PMID:38973154
EGR3 reduces podocyte inflammatory damage in obesity related glomerulopathy by inhibiting the PRMT1/p-STAT3 pathway., PMID:38970508
tRNA-derived small RNA (tsr007330) regulates myocardial fibrosis after myocardial infarction through NAT10-mediated ac4C acetylation of EGR3 mRNA., PMID:38810917
egr3 is a mechanosensitive transcription factor gene required for cardiac valve morphogenesis., PMID:38748804
Yeast-derived particulate beta-glucan induced angiogenesis via regulating PI3K/Src and ERK1/2 signaling pathway., PMID:38685541
EGR3 Polymorphism Is a Potential Susceptibility Factor of Schizophrenia Risk in a Chinese Population., PMID:38657122
lncRNA LINC00941 modulates MTA2/NuRD occupancy to suppress premature human epidermal differentiation., PMID:38649186
Data on electroconvulsive seizure in mice, effects of anesthesia on immediate early gene expression., PMID:38646190
The Transcriptome of BT-20 Breast Cancer Cells Exposed to Curcumin Analog NC2603 Reveals a Relationship between EGR3 Gene Modulation and Cell Migration Inhibition., PMID:38543002
G protein subunit alpha i2's pivotal role in angiogenesis., PMID:38505600
Rapid unleashing of macrophage efferocytic capacity via transcriptional pause release., PMID:38480883
Expression of Early Growth Response 3 in Skin Cancers., PMID:38478384
Transcriptomic analysis of Porphyromonas gingivalis-infected head and neck cancer cells: Identification of PLAU as a candidate prognostic biomarker., PMID:38363001
The role and molecular mechanisms of the early growth response 3 gene in schizophrenia., PMID:38327141
HDAC6-MYCN-CXCL3 axis mediates allergic inflammation and is necessary for allergic inflammation-promoted cellular interactions., PMID:38176167
Interleukin-30 subverts prostate cancer-endothelium crosstalk by fostering angiogenesis and activating immunoregulatory and oncogenic signaling pathways., PMID:38087324
Investigation of Early Growth Response Protein (EGR) Levels in Patients with Fibromyalgia Syndrome: A Cross-Sectional Study., PMID:38008944
EGR3 and estrone are involved in the tamoxifen resistance and progression of breast cancer., PMID:37999751
Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid., PMID:37957540
Development of Bexarotene Analogs for Treating Cutaneous T-Cell Lymphomas., PMID:37947652
IκBζ is an essential mediator of immunity to oropharyngeal candidiasis., PMID:37725983
Mechanism Exploration of Environmental Pollutants on Premature Ovarian Insufficiency: a Systematic Review and Meta-analysis., PMID:37612521
BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution., PMID:37554265
Transcriptional Profile Changes after Noise-Induced Tinnitus in Rats., PMID:37190538
Serial electroconvulsive Seizure alters dendritic complexity and promotes cellular proliferation in the mouse dentate gyrus; a role for Egr3., PMID:37146791
Long noncoding RNA antisense noncoding RNA in the INK4 locus inhibition alleviates airway remodeling in asthma through the regulation of the microRNA-7-5p/early growth response factor 3 axis., PMID:37102654
The EGR3 regulome of infant KMT2A-r acute lymphoblastic leukemia identifies differential expression of B-lineage genes predictive for outcome., PMID:37100882
Construction of Metastasis-Specific Regulation Network in Ovarian Cancer Based on Prognostic Stemness-Related Signatures., PMID:36940084
Inducible CRISPR Epigenome Systems Mimic Cocaine Induced Bidirectional Regulation of Nab2 and Egr3., PMID:36849419
Selective Transcription Factor Blockade Reduces Human Retinal Endothelial Cell Expression of Intercellular Adhesion Molecule-1 and Leukocyte Binding., PMID:36834715
Intrafusal-fiber LRP4 for muscle spindle formation and maintenance in adult and aged animals., PMID:36765071
Prognostic Impact of Aberrantly Expressed Protein-coding Gene Associated With Gastric Cancer's Regulatory T Cells, Based on Online Databases., PMID:36735714
CaMKIV mediates spine growth deficiency of hippocampal neurons by regulation of EGR3/BDNF signal axis in congenital hypothyroidism., PMID:36473844
Bronchial epithelial cell transcriptome shows endotype heterogeneity of asthma in patients with NSAID-exacerbated respiratory disease., PMID:36395984
Alteration of hippocampal Egr3, GABA A receptors, Il-1β, Il6 and Ccl3 expression in audiogenic tremor mice after seizure., PMID:36356419
Egr2 and 3 maintain anti-tumour responses of exhausted tumour infiltrating CD8 + T cells., PMID:36342511
Egr3 as an important regulator of uterine decidualization through targeting Hand2., PMID:36317452
Inhibition of HIPK2 protects stress-induced pathological cardiac remodeling., PMID:36182775
Phylogenetic relationships and the origin of New World soles (Teleostei: Pleuronectiformes: Achiridae): The role of estuarine habitats., PMID:36162736
For research use only. Not for human or drug use.
