Catalog No.
YHF99802
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr547-Met680
Predicted molecular weight
17.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q03692
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
COL10A1, Collagen alpha-1(X) chain
ADAMTS5 Modulates Breast Cancer Development as a Diagnostic Biomarker and Potential Tumour Suppressor, Regulated by BAIAP2-AS1, CRNDE and hsa-miR-135b-3p: Integrated Systems Biology and Experimental Approach., PMID:40472834
Chondroitin sulfate/hyaluronic acid/carboxymethylcellulose macroporous cryogels for controlled delivery of TGF-β1 and IGF-1 to induce chondrogenic differentiation of adipose-derived stem cells in cartilage tissue engineering., PMID:40449777
The Characterization of Serum-Free Media on Human Mesenchymal Stem Cell Fibrochondrogenesis., PMID:40428164
Effect of Hyaluronan in Collagen Biomaterials on Human Macrophages and Fibroblasts In Vitro., PMID:40422831
Promising protein biomarkers for early gastric cancer: clinical performance of combined detection., PMID:40305430
The aggregation tendencies of the signal peptide regions of prone and not prone to aggregate proteins., PMID:40212812
SEMA6D modulates extracellular matrix metabolism in osteoarthritis by inhibiting the AGT/AGTR1a/IL-1β axis., PMID:40184436
The regulatory effect of CoL10A1 to the intracranial vascular invasion and cell proliferation in breast cancer via EMT pathway., PMID:40169690
Anti-fibrotic effects of thrombin inhibition in systemic sclerosis-associated interstitial lung disease: Proof of concept., PMID:40013233
Aberrant expression of collagen type X in solid tumor stroma is associated with EMT, immunosuppressive and pro-metastatic pathways, bone marrow stromal cell signatures, and poor survival prognosis., PMID:39939916
Changes in Gene Expression of the Extracellular Matrix in Patients with Full-Thickness Rotator Cuff Tears of Varying Sizes., PMID:39912080
Urchin-like magnetic nanoparticles loaded with type X collagen siRNA and Stattic to treat triple negative breast cancer under rotating magnetic field like an "enchanted micro-scalpel"., PMID:39864683
Signature of collagen alpha-1(x) gene expression in human cancers and their therapeutic implications., PMID:39787688
Unveiling the shared genes between systemic sclerosis and lung cancer., PMID:39744538
Comparative transcriptome analysis of albino northern snakehead (Channa argus) reveals its various collagen-related DEGs in caudal fin cells., PMID:39739744
COL10A1 Facilitates Prostate Cancer Progression by Interacting With INHBA to Activate the PI3K/AKT Pathway., PMID:39656597
Fibroblast Activation Protein-α Expression in Cancer-Associated Fibroblasts Shows the Poor Survival of Colorectal Cancer via Immune-Mediated Pathways : Implications of FAP in Cancer-Associated Fibroblasts Link Immune Dysregulation to Adverse Survival in Colorectal Cancer., PMID:39623187
Matrigel-encapsulated articular cartilage derived fibronectin adhesion assay derived chondroprogenitors for enhanced chondrogenic differentiation: An in vitro evaluation., PMID:39612596
Plasma COL10A1 Level, a Potential Diagnostic and Prognostic Biomarker for Pancreatic Ductal Adenocarcinoma., PMID:39525356
The Therapeutic Potential of Adipose-Derived Mesenchymal Stem Cell Secretome in Osteoarthritis: A Comprehensive Study., PMID:39457070
Oncogenic mechanisms of COL10A1 in cancer and clinical challenges (Review)., PMID:39392043
A human organoid drug screen identifies α2-adrenergic receptor signaling as a therapeutic target for cartilage regeneration., PMID:39353427
METTL16 Promotes Stability of SYNPO2L mRNA and leading to Cancer Cell Lung Metastasis by Secretion of COL10A1 and attract the Cancer-Associated Fibroblasts., PMID:39247832
Visualization of ER-to-Golgi trafficking of procollagen X., PMID:39245571
The metalloproteinase PAPP-A is required for IGF-dependent chondrocyte differentiation and organization., PMID:39215168
LncRNA HAGLROS promotes breast cancer evolution through miR-135b-3p/COL10A1 axis and exosome-mediated macrophage M2 polarization., PMID:39198393
Osteoporosis in Relation to a Bone-Related Aging Biomarker Derived from the Urinary Proteomic Profile: A Population Study., PMID:39122459
Mutational and transcriptional profile predicts the prognosis of stage IV gastric cancer - Prognostic factors for metastatic gastric cancer., PMID:39043541
FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton., PMID:39012257
Exudative Age-Related Macular Degeneration: Association between Treatment Efficacy and Single-Nucleotide Variants in RAD51B, TRIB1, COL8A1, COL10A1, IL-9, IL-10, and VEGFA Genes., PMID:38999967
Biallelic variants in SLC26A2 cause multiple epiphyseal dysplasia-4 by disturbing chondrocyte homeostasis., PMID:38956600
Short-term response of primary human meniscus cells to simulated microgravity., PMID:38907358
Therapeutic targets for age-related macular degeneration: proteome-wide Mendelian randomization and colocalization analyses., PMID:38903171
Induction of Human Wharton's Jelly of Umbilical Cord Derived Mesenchymal Stem Cells to Be Chondrocytes and Transplantation in Guinea Pig Model with Spontaneous Osteoarthritis., PMID:38891860
Type X collagen knockdown inactivate ITGB1/PI3K/AKT to suppress chronic unpredictable mild stress-stimulated triple-negative breast cancer progression., PMID:38866293
Relationships between matrix mineralization, oxidative metabolism, and mitochondrial structure during ATDC5 murine chondroprogenitor cell line differentiation., PMID:38860464
Upregulation of collagen type X alpha 1 promotes the progress of triple-negative breast cancer via Wnt/β-catenin signaling., PMID:38780151
The role of semaphorin 3A on chondrogenic differentiation., PMID:38727898
Shared biomarkers and mechanisms in idiopathic pulmonary fibrosis and non-small cell lung cancer., PMID:38703565
Osteoporosis GWAS-implicated DNM3 locus contextually regulates osteoblastic and chondrogenic fate of mesenchymal stem/progenitor cells through oscillating miR-199a-5p levels., PMID:38686038
Diverse potential of secretome from natural killer cells and monocyte-derived macrophages in activating stellate cells., PMID:38638443
A synthetic, closed-looped gene circuit for the autonomous regulation of RUNX2 activity during chondrogenesis., PMID:38407380
M2 macrophage-derived exosomal miR-26b-5p regulates macrophage polarization and chondrocyte hypertrophy by targeting TLR3 and COL10A1 to alleviate osteoarthritis., PMID:38374072
Krüppel-like factor 4 modulates the miR-101/COL10A1 axis to inhibit renal fibrosis after AKI by regulating epithelial-mesenchymal transition., PMID:38345033
Early insights into the role of Exoc6B associated with spondyloepimetaphyseal dysplasia with joint laxity type 3 in primary ciliogenesis and chondrogenic differentiation in vitro., PMID:38305850
Structural and Molecular Changes of Human Chondrocytes Exposed to the Rotating Wall Vessel Bioreactor., PMID:38254625
Runx2 deletion in hypertrophic chondrocytes impairs osteoclast mediated bone resorption., PMID:38218304
Experimental validation and pan-cancer analysis identified COL10A1 as a novel oncogene and potential therapeutic target in prostate cancer., PMID:38147021
Proteoglycan inhibition of canonical BMP-dependent cartilage maturation delays endochondral ossification., PMID:38117077
Infection with COVID-19 promotes the progression of pancreatic cancer through the PI3K-AKT signaling pathway., PMID:38063927
For research use only. Not for human or drug use.
