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Recombinant Human CCL8/MCP-2 Protein, N-His

Catalog #:   YHF70301 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P80075
Protein length: Ser29-Pro99
Overview

Catalog No.

YHF70301

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Ser29-Pro99

Predicted molecular weight

10.68 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P80075

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Monocyte chemoattractant protein 2, Small-inducible cytokine A8, HC14, C-C motif chemokine 8, SCYA10, MCP2, SCYA8, CCL8, Monocyte chemotactic protein 2, MCP-2

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human CCL8/MCP-2
References

Systemic immune response alteration in patients with severe pressure ulcers., PMID:40467704

The role of immune checkpoint molecules in PRRSV-2-induced immune modulation: insights from comparative in vivo evaluation including NADC34-like PRRSV., PMID:40459260

Impact of Smoking on Macrophage-Related Chemokines During Initial Peri-Implantitis: A Prospective Cohort Study., PMID:40399133

Shared and Distinctive Inflammation-Related Protein Profiling in Idiopathic Inflammatory Myopathy with/without Anti-MDA5 Autoantibodies., PMID:40357378

Anti-inflammatory properties of Pleione bulbocodioides extract through STING/ NF-κB pathway inhibition., PMID:40345080

Mass spectrometry reveals age-dependent collagen decline in murine atria., PMID:40295212

HSPA2 influences the differentiation and production of immunomodulatory mediators in human immortalized epidermal keratinocyte lines., PMID:40287440

The Role of Chemotactic Cytokines in Tick-Borne Encephalitis., PMID:40214443

Cytokine interactions and chemokine dysregulations in mastitis immunopathogenesis: insights from transcriptomic profiling of milk somatic cells in tropical Sahiwal (Bos indicus) cows., PMID:40196120

Serum type I interferon score as a disease activity biomarker in patients with diffuse cutaneous systemic sclerosis: a retrospective cohort study., PMID:40179922

No Distinct Cytokine, Chemokine, and Growth Factor Blood Profile Associated With Monkeypox Virus Clade IIb Infected Patients., PMID:40156483

Involvement of naïve T cells in the pathogenesis of osimertinib-induced pneumonitis., PMID:40148432

Modulation of Macrophages TLR4-Mediated Transcriptional Response by Lacticaseibacillus rhamnosus CRL1505 and Lactiplantibacillus plantarum CRL1506., PMID:40141330

Plasma Cytokine and Chemokine Profiles Predict Efficacy and Toxicity of Anti-CD19 CAR-T Cell Therapy in Large B-Cell Lymphoma., PMID:40113544

Fisetin alleviates Salmonella typhimurium-induced colitis through the TLR2/TLR4-NF-κB pathway, regulating microbiota, and repressing intracellular bacterial proliferation by focal adhesion kinase., PMID:40106033

Tumor treating fields enhance anti-PD therapy by improving CCL2/8 and CXCL9/CXCL10 expression through inducing immunogenic cell death in NSCLC models., PMID:40098106

Nutrients Lowering Obesity-Linked Chemokines Blamable for Metastasis., PMID:40076892

The connection between 91 inflammatory cytokines and frailty mediated by 1400 metabolites: An exploratory two-step Mendelian randomization analysis., PMID:40054372

MSC transplantation ameliorates depression in lupus by suppressing Th1 cell-shaped synaptic stripping., PMID:40048256

Assessing customized multivalent chemokine-binding peptide treatment in a murine model of coxsackievirus B3 myocarditis., PMID:40009121

Selection Pressure Regulates the Evolution-Structure-Function Paradigm of Monocyte Chemoattractant Protein Family., PMID:39907741

PFKFB3 decreases α-ketoglutarate production while partial PFKFB3 knockdown in macrophages ameliorates arthritis in tumor necrosis factor-transgenic mice., PMID:39870011

[Biomarkers of atherothrombotic and cardioembolic subtypes of acute ischemic stroke]., PMID:39831358

Tumor-initiating cells escape tumor immunity via CCL8 from tumor-associated macrophages in mice., PMID:39774471

The Chemokine System as a Key Regulator of Pulmonary Fibrosis: Converging Pathways in Human Idiopathic Pulmonary Fibrosis (IPF) and the Bleomycin-Induced Lung Fibrosis Model in Mice., PMID:39768150

Circulating inflammatory markers predict depressive symptomatology in COVID-19 survivors., PMID:39700666

Cannabidiol alleviates LPS-inhibited odonto/osteogenic differentiation in human dental pulp stem cells in vitro., PMID:39697062

A biomathematical model of SARS-CoV-2 in Syrian hamsters., PMID:39695178

Chemokine profile in the serum of patients with leptospirosis., PMID:39534703

Characterization, expressional and evolutionary analysis of five fish-specific CCRs (CCR4La, CCR4Lc, CCR12a1, CCR12a2, and CCR12b) in largemouth bass (Micropterus salmoides)., PMID:39461395

A Missing Puzzle in Preclinical Studies-Are CCR2, CCR5, and Their Ligands' Roles Similar in Obesity-Induced Hypersensitivity and Diabetic Neuropathy?-Evidence from Rodent Models and Clinical Studies., PMID:39457105

Microglia and monocyte-derived macrophages drive progression of pediatric high-grade gliomas and are transcriptionally shaped by histone mutations., PMID:39395421

Association of serum interferon alpha-2a levels with disease severity and prognosis in systemic sclerosis., PMID:39388243

Identification of novel cytokine to judge the diagnosis and clinical phenotype of adult-onset Still's disease., PMID:39376199

Altered Cytokine Profile in Clinically Suspected Seronegative Autoimmune Associated Epilepsy., PMID:39314975

Targeting heterogeneous tumor microenvironments in pancreatic cancer mouse models of metastasis by TGF-β depletion., PMID:39298276

Integrating chemokines and machine learning algorithms for diagnosis and bleeding assessment in primary immune thrombocytopenia: A prospective cohort study., PMID:39253817

Secretome and immune cell attraction analysis of head and neck cancers., PMID:39249543

Investigating potential novel therapeutic targets and biomarkers for ankylosing spondylitis using plasma protein screening., PMID:39185422

Transcriptome analyses reveal key features of mouse seminal vesicle during aging., PMID:39167124

Bioinformatic-based Study to Investigate the Structure and Function of Pro-inflammatory Cytokines TNFα and IL-6 Involved in the Pathogenesis of COVID-19., PMID:39118801

Clonal haematopoiesis is associated with major adverse cardiovascular events in patients with hypertrophic cardiomyopathy., PMID:39091134

Identification of shared immune infiltration characteristic molecules in dermatomyositis and nasopharyngeal carcinoma using bioinformatics: Traits in dermatomyositis and nasopharyngeal cancer., PMID:39081134

Muscle cell-derived Ccl8 is a negative regulator of skeletal muscle regeneration., PMID:39051762

Elevated cytokine levels in the central nervous system of cluster headache patients in bout and in remission., PMID:39044165

Targeting the glucocorticoid receptor-CCR8 axis mediated bone marrow T cell sequestration enhances infiltration of anti-tumor T cells in intracranial cancers., PMID:39044027

Inverse Regulation of C-C Chemokine Receptor 3 Oligomerization by Downstream Proteins Indicates Biased Signal Transduction Pathways., PMID:39037351

Streptococcus anginosus: A new pathogen of superficial gastritis, atrophic gastritis and gastric cancer., PMID:39001620

A New Application for Cenicriviroc, a Dual CCR2/CCR5 Antagonist, in the Treatment of Painful Diabetic Neuropathy in a Mouse Model., PMID:39000516

Multiarray screening identifies plasma proteins associated with Th17 cell differentiation and viral defense in coincident asthma and obesity., PMID:38967090

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human CCL8/MCP-2 Protein, N-His [YHF70301]
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