Catalog No.
YHF42601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gly181
Predicted molecular weight
22.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P61328
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fibroblast growth factor homologous factor 1, Myocyte-activating factor, FHF-1, FGF12B, FHF1, FGF-12, FGF12, Fibroblast growth factor 12
Broadening the phenotype associated with pathogenic variants in the FGF12 gene: From developmental and epileptic encephalopathy to drug-responsive epilepsy with favorable cognitive outcome., PMID:40488543
Loss of macrophage fibroblast growth factor 12 attenuates cardiac fibrosis in pressure-overloaded myocardium., PMID:40188526
Production and purification of recombinant long protein isoforms of FGF11 subfamily., PMID:40154621
[Mechanisms of the Anti-Fibrotic Effect of Ginsenoside Rh1 on Hepatic Fibrosis]., PMID:40109461
Single-cell RNA-seq reveals FGF12 as a prognostic biomarker in low-grade endometrial stromal sarcoma., PMID:39676856
FGF12 Positively Regulates Keratinocyte Proliferation by Stabilizing MDM2 and Inhibiting p53 Activity in Psoriasis., PMID:39234815
Uncovering key steps in FGF12 cellular release reveals a common mechanism for unconventional FGF protein secretion., PMID:39158730
Phenotyping of FGF12AV52H mutation in mouse implies a complex FGF12 network., PMID:39142611
Clinical efficacy and gene chip expression analysis of Shenzhu Guanxin recipe granules in patients with intermediate coronary lesions., PMID:38767639
Fibroblast growth factor pathway promotes glycolysis by activating LDHA and suppressing LDHB in a STAT1-dependent manner in prostate cancer., PMID:38764020
FGF12 copy number variant associated with epileptic encephalopathy., PMID:38715525
The intracellular interplay between galectin-1 and FGF12 in the assembly of ribosome biogenesis complex., PMID:38468333
FGF12 restrains mitochondria-dependent ferroptosis in doxorubicin-induced cardiomyocytes through the activation of FGFR1/AMPK/NRF2 signaling., PMID:38349269
Grape seed-derived procyanidin inhibits glyphosate-induced hepatocyte ferroptosis via enhancing crosstalk between Nrf2 and FGF12., PMID:38103315
FGF12: biology and function., PMID:38042708
Comprehensive analyses identify potential biomarkers for encephalitis in HIV infection., PMID:37891420
Capra hircus outliers markers in Brazil: Searching for genomic regions under the action of natural selection., PMID:37882366
Genetic testing in children enrolled in epilepsy surgery program. A real-life study., PMID:37812946
Identification of antisense and sense RNAs of intracrine fibroblast growth factor components as novel biomarkers in colorectal cancer and in silico studies for drug and nanodrug repurposing., PMID:37805185
Voltage-gated sodium channels in genetic epilepsy: up and down of excitability., PMID:37654020
FGF12 regulates cell cycle gene expression and promotes follicular granulosa cell proliferation through ERK phosphorylation in geese., PMID:37494810
FGF homologous factors are secreted from cells to induce FGFR-mediated anti-apoptotic response., PMID:37342898
Generation of a human iPSC line (ZJSHDPi001-A) from peripheral blood mononuclear cells of a patient with Developmental epileptic encephalopathy-47 carrying FGF12 gene mutation (c.334G > A)., PMID:37331110
Biallelic structural variations within FGF12 detected by long-read sequencing in epilepsy., PMID:37286232
Genome-Wide Identification and Characterization of Bovine Fibroblast Growth Factor (FGF) Gene and Its Expression during Adipocyte Differentiation., PMID:36982739
Whole-Genome Sequencing Data Reveal New Loci Affecting Milk Production in German Black Pied Cattle (DSN)., PMID:36980854
The FGF/FGFR system in the microglial neuroinflammation with Borrelia burgdorferi: likely intersectionality with other neurological conditions., PMID:36650549
Integrated transcriptome and proteome revealed that the declined expression of cell cycle-related genes associated with follicular atresia in geese., PMID:36647001
FGF12 is a novel component of the nucleolar NOLC1/TCOF1 ribosome biogenesis complex., PMID:36411431
Genome-wide detection of copy number variation in American mink using whole-genome sequencing., PMID:36096727
Modulating effects of FGF12 variants on NaV1.2 and NaV1.6 being associated with developmental and epileptic encephalopathy and Autism spectrum disorder: A case series., PMID:36029553
Hair Growth Regulation by Fibroblast Growth Factor 12 (FGF12)., PMID:36012732
Exploration of the relationship between hippocampus and immune system in schizophrenia based on immune infiltration analysis., PMID:35983039
Depletion of Fibroblast Growth Factor 12 Restrains the Viability, Stemness, and Motility of Colorectal Cancer., PMID:35860801
Identification of novel susceptibility genes for non-syndromic cleft lip with or without cleft palate using NGS-based multigene panel testing., PMID:35778651
Macrophage-specific FGF12 promotes liver fibrosis progression in mice., PMID:35753047
Brooding Temperature Alters Yolk Sac Absorption and Affected Ovarian Development in Goslings., PMID:35739850
Ameloblastic Carcinoma of the Maxilla: A Rare Case Report and Review of Literature from 1948 to 2021., PMID:35668625
Serological and Molecular Characterization of Hepatitis B Virus Infection in Gastric Cancer., PMID:35592651
A ceRNA Network Composed of Survival-Related lncRNAs, miRNAs, and mRNAs in Clear Cell Renal Carcinoma., PMID:35529267
Genetic loci implicated in meta-analysis of body shape in Africans., PMID:35461751
Severe iatrogenic hypoglycaemia modulates the fibroblast growth factor protein response., PMID:35415885
Fibroblast growth factor 12 attenuated cardiac remodeling via suppressing oxidative stress., PMID:35304156
Plasma Growth Factor Gene Expression and Mammographic Breast Density in Postmenopausal Women., PMID:35288741
MiR-107 Aggravates Oxygen-Glucose Deprivation/Reoxygenation (OGD/R)-Induced Injury Through Inactivating PI3K-AKT Signalling Pathway by Targeting FGF9/FGF12 in PC12 Cells., PMID:35093630
Association of Estrogen-Related Polygenetic Risk Scores with Breast Cancer and Interactions with Alcohol Intake, Early Menarche, and Nulligravida., PMID:35092367
AdipoRon exerts opposing effects on insulin sensitivity via fibroblast growth factor 21-mediated time-dependent mechanisms., PMID:35090894
A Learning Based Framework for Disease Prediction from Images of Human-Derived Pluripotent Stem Cells of Schizophrenia Patients., PMID:35064871