Catalog No.
YHF09001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln23-Arg233
Predicted molecular weight
26.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P55075
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FGF-8, HBGF-8, Heparin-binding growth factor 8, Fibroblast growth factor 8, AIGF, Androgen-induced growth factor, FGF8,FGF8b
Identification of Novel Genetic Variants in a Cohort of Congenital Hypogonadotropic Hypogonadism: Computational Analysis of Pathogenicity Predictions., PMID:40508017
Generation of Prefrontal Cortex Neurons from Human Pluripotent Stem Cells Under Chemically Defined Conditions., PMID:40220092
Fibroblast growth factor 8 (FGF8) induces mitochondrial remodeling in chondrocytes via ERK/AMPK signaling pathway., PMID:40162651
Identifcation of the FGF family as therapeutic targets and prognostic biomarkers in the microenvironment of head and neck squamous cell carcinoma., PMID:40086631
A Cross-Sectional Exploratory Study of Rat Sarcoid (Ras) Activation in Women with and Without Polycystic Ovary Syndrome., PMID:40072105
Differences in Formation of Prepuce and Urethral Groove During Penile Development Between Guinea Pigs and Mice Are Controlled by Differential Expression of Shh, Fgf10 and Fgfr2., PMID:40072077
Patterning effects of FGF17 and cAMP on generation of dopaminergic progenitors for cell replacement therapy in Parkinson's disease., PMID:40071608
Sprouty2/4 deficiency disrupts early signaling centers impacting chondrogenesis in the mouse forelimb., PMID:39906257
Sonic hedgehog and fibroblast growth factor 8 regulate the evolution of amniote facial proportions., PMID:39827295
Integrated analyses of transcriptomes, metabolomes, and proteomes unveil the role of FoXO signaling axis in buck semen cryopreservation., PMID:39756112
The role of sonic hedgehog signaling in the oropharyngeal epithelium during jaw development., PMID:39727066
Fibroblast Growth Factor 8 enhances the chondrogenesis of trunk neural crest cells: a possible gene regulatory network., PMID:39723529
Less, but More: New Insights From Appendicularians on Chordate Fgf Evolution and the Divergence of Tunicate Lifestyles., PMID:39686543
Mef2c- and Nkx2-5-Divergent Transcriptional Regulation of Chick WT1_76127 and Mouse Gm14014 lncRNAs and Their Implication in Epicardial Cell Migration., PMID:39684625
Autosomally dominantly inherited isolated gonadotropin deficiency via maternal assisted reproduction due to SOX10 mutation., PMID:39680495
Fine-tuning of Fgf8 morphogen gradient by heparan sulfate proteoglycans in the extracellular matrix., PMID:39668564
Modeling corticotroph deficiency with pituitary organoids supports the functional role of NFKB2 in human pituitary differentiation., PMID:39607428
Embryonic Flubendiamide Exposure Alters Expression of OTX2 and Other Early Regulators in Domestic Chick Leading to Congenital Eye Defects., PMID:39588769
FGF8 Protects Against Polymicrobial Sepsis by Enhancing the Host's Anti-infective Immunity., PMID:39556487
Overexpression of Fibroblast Growth Factor 8 Is a Predictor of Impaired Survival in Esophageal Squamous Cell Carcinoma and Correlates with ALK/EML4 Alteration., PMID:39518064
FGF8-mediated gene regulation affects regional identity in human cerebral organoids., PMID:39485283
Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma., PMID:39448867
Extracellular vesicles derived from Msh homeobox 1 (Msx1)-overexpressing mesenchymal stem cells improve digit tip regeneration in an amputee mice model., PMID:39384602
Allometry in limb regeneration and scale-invariant patterning as the basis of normal morphogenesis from different sizes of blastemas., PMID:39344771
Flavonoid chrysin activates both TrkB and FGFR1 receptors while upregulates their endogenous ligands such as brain derived neurotrophic factor to promote human neurogenesis., PMID:39331585
Fgf17: A regulator of the mid/hind brain boundary in mammals., PMID:39327214
Proteomics and Bioinformatics Investigations Link Overexpression of FGF8 and Associated Hub Genes to the Progression of Ovarian Cancer and Poor Prognosis., PMID:39309198
A polarized FGF8 source specifies frontotemporal signatures in spatially oriented cell populations of cortical assembloids., PMID:39294368
Fibroblast growth factor 8 promotes in vitro neurite outgrowth of placode-derived petrosal and nodose ganglia to varying degrees., PMID:39209048
Splicing is dynamically regulated during limb development., PMID:39198579
ERK5 promotes autocrine expression to sustain mitogenic balance for cell fate specification in human pluripotent stem cells., PMID:39151429
The possible role of epigenetics in the etiology of hypospadias., PMID:39033034
Diverse Responses of Oligodendrocytes to Different FGF-Family Members: Uncoupling Structure-Function Relationship Within FGF Subfamilies., PMID:39024549
Ectopic Activation of Fgf8 in Dental Mesenchyme Causes Incisor Agenesis and Molar Microdontia., PMID:39000154
Differential effects of the N-terminal helix of FGF8b on the activity of a small-molecule FGFR inhibitor in cell culture and for the extracellular domain of FGFR3c in solution., PMID:38997225
Role of signaling pathways in age-related orthopedic diseases: focus on the fibroblast growth factor family., PMID:38902808
Unravelling the molecular landscape of endometrial cancer subtypes: insights from multiomics analysis., PMID:38775562
Spontaneous differentiation of human induced pluripotent stem cells to odorant-responsive olfactory sensory neurons., PMID:38740002
Genes involved in metastasis in oral squamous cell carcinoma: A systematic review., PMID:38665153
Ligand bias underlies differential signaling of multiple FGFs via FGFR1., PMID:38568193
The pathogenic mechanism of syndactyly type V identified in a Hoxd13Q50R knock-in mice., PMID:38561387
Characterization of the development of the high-acuity area of the chick retina., PMID:38548147
Poly (Adp-Ribose) Polymerase-1 (PARP-1) Is a Good Prognostic Marker for Pancreatic/Periampullary Cancers., PMID:38530967
FGF17 protects cerebral ischemia reperfusion-induced blood-brain barrier disruption via FGF receptor 3-mediated PI3K/AKT signaling pathway., PMID:38522639
New candidate genes potentially involved in Zika virus teratogenesis., PMID:38522248
Early embryogenesis in CHDFIDD mouse model reveals facial clefts and altered cranial neurogenesis., PMID:38511331
[Rho kinase inhibitor Y27632 promotes survival of human induced pluripotent stem cells during differentiation into functional midbrain dopaminergic progenitor cells in vitro]., PMID:38501408
VEGF and Other Gene Therapies Improve Flap Survival-A Systematic Review and Meta-Analysis of Preclinical Studies., PMID:38473869
The Osteoblast Transcriptome in Developing Zebrafish Reveals Key Roles for Extracellular Matrix Proteins Col10a1a and Fbln1 in Skeletal Development and Homeostasis., PMID:38397376
Exposure to tris (1,3-dichloro-2-propyl) phosphate affects the embryonic cardiac development of Oryzias melastigma., PMID:38327441
For research use only. Not for human or drug use.
