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Recombinant Human NOS3 Protein, N-His

Catalog #:   YHD84201 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P29474
Protein length: Met1-Lys192
Overview

Catalog No.

YHD84201

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Met1-Lys192

Predicted molecular weight

22.86 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P29474

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Constitutive NOS, NOSIII, eNOS, Endothelial NOS, EC-NOS, Nitric oxide synthase, endothelial, NOS type III, NOS3, cNOS

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human NOS3 protein
References

Identification and Validation of Oxidative Stress-Related Diagnostic Marker Genes and Immune Landscape in Ulcerative Interstitial Cystitis by Integrating Bioinformatics and Machine Learning., PMID:40497148

HTLV-1 infection altered expression of CCR2, CXCR2, eNOS genes, and oxidative stress in aorta and heart of male mice., PMID:40495291

Lupus nephritis serum induces changes in gene expression in human glomerular endothelial cells, which is modulated by L-sepiapterin: implications for redox-mediated endothelial dysfunction., PMID:40480647

Increased CSF drainage by non-invasive manipulation of cervical lymphatics., PMID:40468071

miR-486-5p Inhibits eNOS and Angiogenesis in Cultured Endothelial Cells by Targeting MAML3., PMID:40432288

Proteomic surveys of the mouse heart unveil cardiovascular responses to nitric oxide/cGMP signaling deficiencies., PMID:40425728

ICAM1 778G>A (rs1799969), ADD1 1378G>T (rs4961), NPPA 553T>C (rs5065), and NOS3 894G>T (rs1799983) Variants in Infants with Gastroschisis from Western Mexico., PMID:40421935

Integrating LC-MS and molecular docking technology to investigate the effect of Spatholobi caulis flavonoids in alleviating primary dysmenorrhea via regulating the RhoA/ROCK pathway., PMID:40414437

Inducible nitric oxide synthase (iNOS): More than an inducible enzyme? Rethinking the classification of NOS isoforms., PMID:40389042

Study on the mechanism of acteoside in treating purinomycin aminonucleoside-induced chronic glomerulonephritis in childhood rats based on Cxcr4-PI3K-Akt-eNOS axis., PMID:40389008

Molecular characterization of NOS3 and SOD1 genes as markers for detecting patients with breast cancer., PMID:40388013

DNA Methylation of iNOS, eNOS, TP53 and LINE-1 in Gingival Tissues of Cigarette Smokers, Heat-Not-Burn Smokers and Never Smokers: An Exploratory Study., PMID:40387376

Combined effects and potential mechanisms of volatile organic compounds on thyroid disease in the US population: An integrated epidemiological and computational toxicology study., PMID:40378728

Adropin contributes to the nephro-protective effect of vitamin D in renal aging in a rat model via MAPK/HIFα/VEGF/eNOS mechanism., PMID:40348136

Rehmanniae Radix Praeparata in Blood Deficiency Syndrome: UPLC-Q-TOF-MS Profiling, Network Pharmacology, and PI3K-AKT Activation., PMID:40332770

Unique and overlapping mechanisms of valbenazine, deutetrabenazine, and vitamin E for tardive dyskinesia., PMID:40268947

Safflower injection against obesity-induced mice podocyte injury by improving insulin resistance through increasing renal INSR and eNOS expression., PMID:40259553

Characterization of two novel angiotensin converting enzyme-inhibitory peptides from yellow tuna peptides: Inhibitory mechanism, transport route and network pharmacology analysis., PMID:40253180

Intermedin protects peritubular capillaries by inhibiting eNOS uncoupling through AMPK/GTPCH-I/BH4 pathway and alleviate CKD following AKI., PMID:40228707

Modulation of VEGF/eNOS/TGF-β Axis by Piracetam as a New Avenue to Ameliorate Valproic Acid-Induced Placental Toxicity and Teratogenicity in Rats., PMID:40226982

Analysis of Gene Polymorphisms in Benign Prostate Hyperplasia Patients Receiving Combination Therapy of Alpha Blocker (a-Blocker) and 5-Alpha Reductase Inhibitor (5-ARI)., PMID:40223852

Increased cGMP improves microvascular exercise training adaptations in diet-induced obesity., PMID:40204283

Role of adenosine A3 receptor and endothelial nitric oxide synthase in patients with traumatic hemorrhagic shock., PMID:40198384

Alleviation of accelerated diabetic atherogenesis in STZ-treated apoE/NOX1 DKO mice, apoE-/-/tg-EC-DHFR mice, and by folic acid., PMID:40184644

Ferulic acid inhibits ox-LDL-induced ferroptosis and apoptosis in RAW 264.7 cells via the HIF-1 signaling pathway., PMID:40170728

Ursolic Acid Ameliorates Vascular Oxidative Stress and Upregulates Endothelial Nitric Oxide Synthase Gene in Male Wistar Rats with High-carbohydrate High-fat Diet-induced Metabolic Syndrome., PMID:40156788

Mechanistic Insights into Salvigenin for Glucocorticoid-Induced Femoral Head Osteonecrosis: A Network Pharmacology and Experimental Study., PMID:40149590

FTO and NOS3 genes associated with pediatric obesity: Corações de Ouro Preto study., PMID:40114142

A Light-Activatable Nitric Oxide Donor for Targeted Glaucoma Therapy with Real-Time Monitoring Capabilities., PMID:40103449

RasGRP2 Attenuates TAGE Modification of eNOS in Vascular Endothelial Cells., PMID:40101981

Genetic Associations with the Susceptibility to High-Altitude Pulmonary Edema in the Japanese Population., PMID:40094446

Radiofrequency electromagnetic field ınhibits HIF-1 alpha and activates eNOS signaling to prevent intestinal damage in a model of mesenteric artery ischemia in rats., PMID:40084245

Adipokine levels and T786C polymorphism of eNOS gene promoter correlation in patients with arterial hypertension., PMID:40073405

Endothelial dysfunction promotes age-related reorganization of collagen fibers and alters aortic biomechanics in mice., PMID:40062975

L-Citrulline Alleviates Testicular Ischemia/Reperfusion Injury in Rats by Modulating eNOS/iNOS Induced Nitric Oxide Production, Inflammation, and Apoptosis., PMID:40059720

Network pharmacology mechanism of Rosmarinus officinalis L.(Rosemary) to improve cell viability and reduces apoptosis in treating Alzheimer's disease., PMID:40055645

Upregulation of COX-2 and NADPH Oxidase and Reduced eNOS in Perivascular Adipose Tissue Are Associated With Resistance Artery Dysfunction and Hypertension in Naturally Aged Mice., PMID:40037608

Air pollution and prostate cancer: Unraveling the connection through network toxicology and machine learning., PMID:40022828

Effects of 3-(4-Hydroxy-3-methoxyphenyl)propionic Acid on Regulating Oxidative Stress and Muscle Fiber Composition., PMID:40004996

Unveiling the Negative Synergistic Effect of Wall Shear Stress and Insulin on Endothelial NO Dynamics by Mathematical Modeling., PMID:39969626

Eucalyptol attenuates indomethacin-induced gastric ulcers in rats by modulating the ICAM-1, eNOS and COX/LOX pathways: Insights from in silico, in vitro and in vivo approaches., PMID:39965739

Acetylcholine-loaded nanoparticles protect against doxorubicin-induced toxicity inin vitrocardiac spheroids., PMID:39965540

The association of endothelial nitric oxide synthase (eNOS) gene polymorphisms and diabetic retinopathy among patients with type 2 diabetes: A case-control study., PMID:39959179

GelMA@LNP/AST Promotes eNOS-Dependent Angiogenesis Through Autophagy Activation for the Treatment of Hind Limb Ischemia., PMID:39958322

Panaxadiol Attenuates Neuronal Oxidative Stress and Apoptosis in Cerebral Ischemia/Reperfusion Injury via Regulation of the JAK3/STAT3/HIF-1α Signaling Pathway., PMID:39957706

Chronic intermittent hypobaric hypoxia prevents pulmonary arterial hypertension through maintaining eNOS homeostasis., PMID:39954797

Genetic association of MIR-449B, GCLC, eNOS, SORD, and ENPP1 with diabetic retinopathy., PMID:39952424

Tadalafil Ameliorates Chronic Ischemia-Associated Bladder Overactivity in Fructose-Fed Rats by Exerting Pelvic Angiogenesis and Enhancing p-eNOS Expression., PMID:39941129

Endothelial cell-specific postnatal deletion of Nos3 preserves intraocular pressure homeostasis via macrophage recruitment and NOS2 upregulation., PMID:39932792

Acacetin reduces endoplasmic reticulum stress through the P-eNOS/PERK signaling pathway to attenuate MGO-induced vascular endothelial cell dysfunction., PMID:39927486

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human NOS3 Protein, N-His [YHD84201]
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