Catalog No.
RHC27705
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Monoclonal
Target
T-cell surface glycoprotein CD3 delta chain, CD3D, T-cell receptor T3 delta chain, T3D, CD3d, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface glycoprotein CD3 gamma chain, T-cell receptor T3 gamma chain, CD3g, T3G, CD3G, CD3Z, CD247, TCRZ, T-cell receptor T3 zeta chain, T3Z, T-cell surface glycoprotein CD3 zeta chain
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
IHC-p
Form
Liquid
Storage buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4D86
Effective Use of BCMA-Targeting Bispecific T-Cell-Engaging Antibody in Treatment Refractory LRP4-positive Myasthenia Gravis., PMID:40534130
Diatom-Based Artificial Antigen-Presenting Cells: A Novel Approach for Adaptive Immune Modulation., PMID:40530806
The next generation of immunotherapies for lung cancers., PMID:40528044
Type 1 diabetes mellitus prevention: present and future., PMID:40527975
[Research on the inhibitory effects of evodiamine on activated T cell proliferation]., PMID:40525340
Effect of Metformin on vascular endothelial injury in patients with non-small cell lung cancer treated with chemotherapy combined with bevacizumab., PMID:40522519
Flow Cytometric Assessment of TRBC1 Expression for the Diagnosis of T-Cell Lymphoma: Clinical Utility and Pitfalls Related to T-Cell Clones of Uncertain Significance., PMID:40521694
Immunogenomic characteristics and prognostic implications of terminally exhausted CD8+ T cells in colorectal cancers., PMID:40519933
A fc-engineered NKG2D × B7-H3 bispecific antibody enhances the antitumor activity by orchestrating cytotoxic lymphocytes., PMID:40516256
Diagnostic significance of carcinoembryonic antigen and anti-MDA5 antibodies in polymyositis/dermatomyositis-associated rapidly progressive interstitial lung disease., PMID:40516211
Pooled biomarker analysis of the association of baseline T regulatory cells with response and T-cell recovery profiles with blinatumomab treatment., PMID:40515477
[Modern systemic treatment-bispecific antibodies and CAR-T cell therapy : Clinical management, mechanisms of action, outcomes]., PMID:40514410
A simple and low-cost paper chip-based smartphone sensor for enumeration of T lymphocyte subsets., PMID:40513165
IL-33 Has a Protective Effect Against Perinatal Listeriosis by Regulating Mitophagy of CD8+ T Lymphocytes., PMID:40512525
Influence of Ovophospholipids on Lymphocyte Subsets and Humoral Immune Response in Mice., PMID:40509141
T-Cell Engager Therapy in Prostate Cancer: Molecular Insights into a New Frontier in Immunotherapy., PMID:40507301
High-Sensitivity Flow Cytometric Detection of a Small Circulating Population of Nodal T-Follicular Helper Cell Lymphoma Angioimmunoblastic Type Cells., PMID:40503539
QSP modeling of loncastuximab tesirine with T-cell-dependent bispecific antibodies guides dose-regimen strategy., PMID:40500294
Low-dose photodynamic therapy promotes vascular E-selectin expression in chest malignancies, improving immune infiltration and tumor control., PMID:40500108
Autoreactive T Cells and Cytokine Stress Drive β-Cell Senescence Entry and Accumulation in Type 1 Diabetes., PMID:40498653
Harnessing delta-like ligand 3: bridging biomarker discovery to next-generation immunotherapies in refractory small cell lung cancer., PMID:40496850
Treatment of Older Adults with Newly Diagnosed Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia., PMID:40494331
Combining CD3/GD2 bispecific T cell engager with human Vγ9Vδ2 T cells facilitates neuroblastoma cell targeting and killing in vitro., PMID:40489497
LAG3 Is Expressed on Muscle-Infiltrating Cytotoxic T Cells, but Scarce on Circulating T Cells, in Patients With Inclusion Body Myositis., PMID:40485502
Targeting IL13Rα2 in melanoma with a bispecific T-cell engager: expression profiling and preclinical evaluation., PMID:40484645
One-year remission of therapy-resistant SLE after a single course with the bispecific CD3: BCMA antibody teclistamab, but induction of a non-infectious Crohn's-like inflammatory bowel disease., PMID:40450406
CD20×CD3 Bispecific Antibodies in B-NHL: A Review of Translational Science, Pharmacokinetics, Pharmacodynamics, and Dose Strategy in Clinical Research., PMID:40471801
The immunosuppressive effect of glucocorticoids in human primary T cells is mainly mediated via a rapid inhibition of the IL-2/IL-2R signaling axis., PMID:40468327
Optimization of a novel 2+2 BCMA x CD3 bispecific antibody for minimized cytokine release and potent efficacy., PMID:40465538
Predictive factors and nomogram for the risk of cytokine release syndrome with anti-CD3 × CD20 bispecific antibodies for Chinese patients., PMID:40464994
T-cell activation enhances anti-HER2-mediated antibody-dependent cellular cytotoxicity in gastric cancer., PMID:40455140
Latent EBV enhances the efficacy of anti-CD3 mAb in Type 1 diabetes., PMID:40447640
Treatment of small cell lung cancer; advances and future prospects., PMID:40446464
Ovalbumin-specific regulatory T cells differentiated from the naïve phenotype (CD44loCD62Lhi) in mesenteric lymph nodes stably suppress enteropathy even in severe food-allergic mice., PMID:40446078
The prevalence and associated risk factors of post-transplant Toxoplasma gondii infection among kidney transplant recipients and patients with uremia in Central-southern China., PMID:40446014
Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency., PMID:40445758
cDC1s Promote Atherosclerosis via Local Immunity and Are Targetable for Therapy., PMID:40444360
Impact of CD3 expression on outcome in pediatric anaplastic large cell lymphoma., PMID:40444097
Bispecific antibody targeting shared indel-derived neoantigen of APC., PMID:40443649
Machine-learning-assisted universal protein activation in living mice., PMID:40436016
Potential of bone marrow mesenchymal stem cells in iodine-induced autoimmune thyroiditis therapy., PMID:40435196
A Genome-Wide Screening of Novel Immunogenic TrLSDV103 Protein of Lumpy Skin Disease Virus and Its Application for DIVA., PMID:40432413
Unsupervised Clustering of Cell Populations in Germinal Centers Using Multiplexed Immunofluorescence., PMID:40427719
Single-Agent and Associated Therapies with Monoclonal Antibodies: What About Follicular Lymphoma?, PMID:40427101
The Prognostic Impact of the Tumor Immune Microenvironment in Synovial Sarcoma: An Immunohistochemical Analysis Using Digital Pathology and Conventional Interpretation., PMID:40423041
Chimeric Autoantibody Receptor- and/or Peptide-MHC-Based CAR Therapies for Targeted Elimination of Antigen-Specific B or T Cells in Hypersensitivity Disorders Such as Allergies and Autoimmune Diseases., PMID:40422256
Phase 1b/2 study of ADG106, a 4-1BB/CD137 agonist, in combination with toripalimab in patients with advanced solid tumors., PMID:40421181
Targeted fusion of antibody-secreting cells: Unlocking monoclonal antibody production with hybridoma technology., PMID:40418588
[Protective аction of ginseng root extract on myofibril apoptosis and immune response in rats after exhausting physical exercise. Part II. Effect of ginseng root extract on immunity and regulation of energy metabolism]., PMID:40418135
Engaging T cells for cleanup., PMID:40416957
For research use only. Not for human or drug use.
