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Recombinant Human SOAT2 Protein, N-His-KSI

Catalog #:   YHB34902 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: O75908
Protein length: [Glu2-Phe120] & [Gly253-Arg293] & [Leu370-Arg417]
Overview

Catalog No.

YHB34902

Expression system

E. coli

Species

Human

Protein length

[Glu2-Phe120] & [Gly253-Arg293] & [Leu370-Arg417]

Predicted molecular weight

40.40 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

O75908

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% SKL, 1mM EDTA, 5% Trehalose, 2% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

ACAT2, Cholesterol acyltransferase 2, Acyl-coenzyme A:cholesterol acyltransferase 2, SOAT2, ACAT-2, ACACT2, Sterol O-acyltransferase 2

Data Image
  • SDS-PAGE
    SDS-PAGE for Recombinant Human SOAT2 Protein
References

The impact of de novo lipogenesis on predicting survival and clinical therapy: an exploration based on a multigene prognostic model in hepatocellular carcinoma., PMID:40533802

Transcriptomic and metabonomic profiling unveils the mechanism of Tartary buckwheat and kiwi co-fermentation products in hyperlipidemia treatment., PMID:40520184

Identification of circulating tumor cells marker genes as prognostic signature in triple-negative breast cancer., PMID:40413298

Father's adolescent body silhouette is associated with offspring asthma, lung function and BMI through DNA methylation., PMID:40410506

Association of Increased SOAT2 Expression with Abnormal Cholesterol Esterification and Testosterone Deficiency in Late-Onset Hypogonadism Rats., PMID:40396327

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2-mediated increase of SOAT2 RNA methylation., PMID:40227950

Elucidating the mechanism of phthalates induced osteoporosis through network toxicology and molecular docking., PMID:39884015

Dietary Tannic Acid Promotes Growth Performance and Resistance Against Aeromonas hydrophila Infection by Improving the Antioxidative Capacity and Intestinal Health in the Chinese Soft-Shelled Turtle (Pelodiscus sinensis)., PMID:39857447

Increased SOAT2 expression in aged regulatory T cells is associated with altered cholesterol metabolism and reduced anti-tumor immunity., PMID:39805872

ELAVL1-dependent SOAT2 exacerbated the pancreatitis-like cellular injury of AR42J cells induced by hyperstimulation with caerulein., PMID:39588852

Fatty acid metabolism prognostic signature predicts tumor immune microenvironment and immunotherapy, and identifies tumorigenic role of MOGAT2 in lung adenocarcinoma., PMID:39478862

Drimane sesquiterpene esters produced by Aspergillus insuetus BF-1613 as inhibitors of sterol O-acyltransferase., PMID:39385005

siRNA/CS-PLGA Nanoparticle System Targeting Knockdown Intestinal SOAT2 Reduced Intestinal Lipid Uptake and Alleviated Obesity., PMID:39297413

Investigating the potential mechanism and therapeutic effects of SLXG for cholesterol gallstone treatment., PMID:39059092

Comprehensive prognostic and immune analysis of sterol O-acyltransferase 1 in patients with hepatocellular carcinoma., PMID:38577529

Soat2 inhibitor avasimibe alleviates acute pancreatitis by suppressing acinar cell ferroptosis., PMID:38376541

Insights into sequence characteristics and evolutionary history of DGATs in arthropods., PMID:38266530

ACAT2 may be a novel predictive biomarker and therapeutic target in lung adenocarcinoma., PMID:38213102

Placental extract suppresses lipid droplet accumulation by autophagy during the differentiation of adipose-derived mesenchymal stromal/stem cells into mature adipocytes., PMID:37974253

Pigment Identification and Gene Expression Analysis during Erythrophore Development in Spotted Scat (Scatophagus argus) Larvae., PMID:37895036

DNA Methylation of Genes Participating in Hepatic Metabolisms and Function in Fetal Calf Liver Is Altered by Maternal Undernutrition during Gestation., PMID:37445858

The Immune Landscape and Molecular Subtypes of Pediatric Crohn's Disease: Results from In Silico Analysis., PMID:37108957

Comparative Analysis of miRNA-mRNA Regulation in the Testes of Gobiocypris rarus following 17α-Methyltestosterone Exposure., PMID:36835651

Identification of the prognostic value of Th1/Th2 ratio and a novel prognostic signature in basal-like breast cancer., PMID:36694223

Targeting Sterol O-Acyltransferase/Acyl-CoA:Cholesterol Acyltransferase (ACAT): A Perspective on Small-Molecule Inhibitors and Their Therapeutic Potential., PMID:36473091

Plasma FA composition in familial LCAT deficiency indicates SOAT2-derived cholesteryl ester formation in humans., PMID:35598637

Antihyperlipidemic Activity of Gut-Restricted LXR Inverse Agonists., PMID:35417135

HNF1A POU Domain Mutations Found in Japanese Liver Cancer Patients Cause Downregulation of HNF4A Promoter Activity with Possible Disruption in Transcription Networks., PMID:35327967

ACAT2 as a novel therapeutic target to treat fatty liver disease., PMID:35143097

Soat2 ties cholesterol metabolism to β-oxidation and glucose tolerance in male mice., PMID:34982494

Acyl-Coenzyme A: Cholesterol Acyltransferase (ACAT) in Cholesterol Metabolism: From Its Discovery to Clinical Trials and the Genomics Era., PMID:34436484

High expression of Sterol-O-Acyl transferase 1 (SOAT1), an enzyme involved in cholesterol metabolism, is associated with earlier biochemical recurrence in high risk prostate cancer., PMID:34326474

Sterol O-acyltransferase 2 chaperoned by apolipoprotein J facilitates hepatic lipid accumulation following viral and nutrient stresses., PMID:33980978

Combined Lipidomics and Network Pharmacology Study of Protective Effects of Salvia miltiorrhiza against Blood Stasis Syndrome., PMID:33790973

A Combination of Single Nucleotide Polymorphisms is Associated with the Interindividual Variability of Cholesterol Bioavailability in Healthy Adult Males., PMID:32996248

Gene expression in rat placenta after exposure to di(2-ethylhexyl) phthalate., PMID:32909833

Delineation of metabolic responses of Npc1-/-nih mice lacking the cholesterol-esterifying enzyme SOAT2 to acute treatment with 2-hydroxypropyl-β-cyclodextrin., PMID:32890578

Whole-exome sequencing and genome-wide association studies identify novel sarcopenia risk genes in Han Chinese., PMID:32478482

The Anti-atherogenic Activity of Beauveriolide Derivative BVD327, a Sterol O-Acyltransferase 2-Selective Inhibitor, in Apolipoprotein E Knockout Mice., PMID:32475917

Voluhemins, new inhibitors of sterol O-acyltransferase, produced by Volutella citrinella BF-0440., PMID:32467602

Generation of new hepatocyte-like in vitro models better resembling human lipid metabolism., PMID:32058035

Enhanced acyl-CoA:cholesterol acyltransferase activity increases cholesterol levels on the lipid droplet surface and impairs adipocyte function., PMID:31727739

Role of Neutral Sphingomyelinase-2 (NSM 2) in the Control of T Cell Plasma Membrane Lipid Composition and Cholesterol Homeostasis., PMID:31681760

Influence of dietary linseed oil as substitution of fish oil on whole fish fatty acid composition, lipid metabolism and oxidative status of juvenile Manchurian trout, Brachymystax lenok., PMID:31554849

Ontogenesis and Modulation of Intestinal Unesterified Cholesterol Sequestration in a Mouse Model of Niemann-Pick C1 Disease., PMID:31312996

Genetic depletion of Soat2 diminishes hepatic steatosis via genes regulating de novo lipogenesis and by GLUT2 protein in female mice., PMID:30630736

Helvamide, a new inhibitor of sterol O-acyltransferase produced by the fungus Aspergillus nidulans BF-0142., PMID:30305686

Celludinones, new inhibitors of sterol O-acyltransferase, produced by Talaromyces cellulolyticus BF-0307., PMID:30177721

Overexpression of transforming growth factor β induced factor homeobox 1 represses NPC1L1 and lowers markers of intestinal cholesterol absorption., PMID:29980051

Quantifying and Localizing the Mitochondrial Proteome Across Five Tissues in A Mouse Population., PMID:29945935

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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Recombinant Human SOAT2 Protein, N-His-KSI [YHB34902]
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