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Anti-KSHV/HHV8 K8 Antibody (R4D75)

Catalog #:   RVV44301 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: IF, WB
Overview

Catalog No.

RVV44301

Species reactivity

Human herpesvirus 8 type P (isolate GK18) (HHV-8) (Kaposi's sarcoma-associated herpesvirus)

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Tested applications

IF: 1:25-1:50, WB: 1:500-1:2000

Target

K8

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4D75

Data Image
  • Immunohistochemical
    Immunocytochemistry analysis of TPA induced BCBL-1 cells (A) and uninduced BCBL-1 cells (B) using KSHV K8 mouse mAb with AEC staining.
  • Western blot
    Western blot analysis using KSHV K8 mouse mAb against BCBL-1 (1) and TPA induced BCBL-1 (2) cell lysate.
References

Kaposi Sarcoma-Associated Herpesvirus Risk and Disease in Kidney Donors and Transplant Recipients with HIV in the United States., PMID:40324947

Kaposi's sarcoma herpesvirus seroprevalence among blood donors in Uganda., PMID:40172229

Increased human herpesvirus-8 neutralizing response during remission from Kaposi's sarcoma., PMID:39565219

Development of KSHV vaccine platforms and chimeric MHV68-K-K8.1 glycoprotein for evaluating the in vivo immunogenicity and efficacy of KSHV vaccine candidates., PMID:39475238

Kaposi sarcoma-associated herpesvirus complement control protein (KCP) and glycoprotein K8.1 are not required for viral infection in vitro or in vivo., PMID:38767375

Antibody profiling and predictive modeling discriminate between Kaposi sarcoma and asymptomatic KSHV infection., PMID:38381773

Evaluation of human herpesvirus-8 viremia and antibody positivity in patients with HIV infection with human herpesvirus-8-related diseases., PMID:38103015

Epstein-Barr virus (EBV) antibody changes over time in a general population cohort in rural Uganda, 1992-2008., PMID:37775773

High Seroprevalence of Kaposi Sarcoma-Associated Herpesvirus in Men Who Have Sex With Men With HIV in the Southern United States., PMID:37096147

Distinctive Kaposi Sarcoma-Associated Herpesvirus Serological Profile during Acute Plasmodium falciparum Malaria Episodes., PMID:37047683

Seroprevalence of Kaposi's sarcoma-associated herpesvirus and risk factors in Jiuquan area, China., PMID:35922376

Kaposi's sarcoma-associated herpesvirus T cell responses in HIV seronegative individuals from rural Uganda., PMID:34916520

Seroprevalence of human herpesvirus 8 in Ireland among blood donors, men who have sex with men, and heterosexual genitourinary medicine and infectious diseases clinic attendees., PMID:33475183

Malaria during pregnancy and transplacental transfer of Kaposi sarcoma-associated herpesvirus (KSHV) antibodies: a cohort study of Kenyan mother and child pairs., PMID:33292357

Malaria Is Associated With Kaposi Sarcoma-Associated Herpesvirus Seroconversion in a Cohort of Western Kenyan Children., PMID:33249494

Variation in KSHV prevalence between geographically proximate locations in Uganda., PMID:32714434

Kaposi Sarcoma-Associated Herpesvirus Infection and Endemic Burkitt Lymphoma., PMID:32072172

Kaposi's sarcoma-associated herpesvirus seropositivity is associated with parasite infections in Ugandan fishing communities on Lake Victoria islands., PMID:31618208

Glycoprotein K8.1A of Kaposi's Sarcoma-Associated Herpesvirus Is a Critical B Cell Tropism Determinant Independent of Its Heparan Sulfate Binding Activity., PMID:30567992

Determinants of Gammaherpesvirus Shedding in Saliva Among Ugandan Children and Their Mothers., PMID:29762709

Age of Infection with Kaposi Sarcoma-Associated Herpesvirus and Subsequent Antibody Values Among Children in Uganda., PMID:29369149

Kaposi Sarcoma-Associated Herpesvirus in a Rural Ugandan Cohort, 1992-2008., PMID:29099933

The Kaposi's sarcoma-associated herpesvirus (KSHV) non-structural membrane protein K15 is required for viral lytic replication and may represent a therapeutic target., PMID:28938025

SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication., PMID:28212444

Rapid Multiplexed Immunoassay for Detection of Antibodies to Kaposi's Sarcoma-Associated Herpesvirus., PMID:27669509

Epidemiology of Kaposi's sarcoma-associated herpesvirus in HIV-1-infected US persons in the era of combination antiretroviral therapy., PMID:26035321

Association between malaria exposure and Kaposi's sarcoma-associated herpes virus seropositivity in Uganda., PMID:25611008

Trends in Kaposi's sarcoma-associated Herpesvirus antibodies prior to the development of HIV-associated Kaposi's sarcoma: a nested case-control study., PMID:25395177

Heterogeneity and breadth of host antibody response to KSHV infection demonstrated by systematic analysis of the KSHV proteome., PMID:24675986

Risk factors for Kaposi's sarcoma among HIV-positive individuals in a case control study in Cameroon., PMID:24631417

The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis., PMID:24335295

Efficient infection of a human B cell line with cell-free Kaposi's sarcoma-associated herpesvirus., PMID:24257608

Seroprevalence of Kaposi's sarcoma-associated herpesvirus among men who have sex with men in Japan., PMID:23588730

Quantitative determinations of anti-Kaposi sarcoma-associated herpesvirus antibody levels in men who have sex with men., PMID:23541691

Chromatin immunoprecipitation and microarray analysis suggest functional cooperation between Kaposi's Sarcoma-associated herpesvirus ORF57 and K-bZIP., PMID:23365430

Selective killing of Kaposi's sarcoma-associated herpesvirus lytically infected cells with a recombinant immunotoxin targeting the viral gpK8.1A envelope glycoprotein., PMID:22377676

Prevalence and predictors of kaposi sarcoma herpes virus seropositivity: a cross-sectional analysis of HIV-infected adults initiating ART in Johannesburg, South Africa., PMID:22093140

Differences in Kaposi sarcoma-associated herpesvirus-specific and herpesvirus-non-specific immune responses in classic Kaposi sarcoma cases and matched controls in Sicily., PMID:21740480

Human herpesvirus 8 seropositivity among sexually active adults in Uganda., PMID:21712983

Human herpesvirus 8 infection in children and adults in a population-based study in rural Uganda., PMID:21273188

Geographic heterogeneity of prevalence of the human herpesvirus 8 in sub-Saharan Africa: clues about etiology., PMID:21074111

Sex and geographic patterns of human herpesvirus 8 infection in a nationally representative population‐based sample in Uganda., PMID:20863232

Kaposi's Sarcoma Associated-Herpes Virus (KSHV) Seroprevalence in Pregnant Women in South Africa., PMID:20807396

Patterns of antibodies against latent and lytic antigens of human herpesvirus 8 in an endemic population and patients with Kaposi's sarcoma in Mozambique., PMID:20648612

Distinct profiles of antibodies to Kaposi sarcoma-associated herpesvirus antigens in patients with Kaposi sarcoma, multicentric Castleman disease, and primary effusion lymphoma., PMID:20443737

Detection of antibodies to Kaposi's sarcoma-associated herpesvirus: a new approach using K8.1 ELISA and a newly developed recombinant LANA ELISA., PMID:20211626

Immune response to intranasal and intraperitoneal immunization with Kaposi's sarcoma-associated herpesvirus in mice., PMID:20206669

[Research on co-infections of HIV and human herpesvirus-8 among the Uygur high-risk groups in a city, Xinjiang]., PMID:20137516

Kaposi's sarcoma-associated herpesvirus glycoproteins B and K8.1 regulate virion egress and synthesis of vascular endothelial growth factor and viral interleukin-6 in BCBL-1 cells., PMID:19955303

Seroepidemiology of human herpesvirus 8 (HHV-8) infection in injecting drug users., PMID:19698211

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-KSHV/HHV8 K8 Antibody (R4D75) [RVV44301]
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