Catalog No.
RHP06501
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200
Target
Impedes mitogenic signal propagation, BRCA1-associated protein, IMP, RING-type E3 ubiquitin transferase BRAP2, RING finger protein 52, RNF52, BRAP, Renal carcinoma antigen NY-REN-63, BRAP2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q7Z569
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4D06
Immunohistochemical validation studies in effusion cytology: A cautionary tale., PMID:31116504
BRCA1 Reflects Myocardial Adverse Remodeling in Idiopathic Dilated Cardiomyopathy., PMID:27496484
The Prognostic Value of BRCA1 and PARP Expression in Epithelial Ovarian Carcinoma: Immunohistochemical Detection., PMID:27362900
CTLA-4 Blockade Synergizes Therapeutically with PARP Inhibition in BRCA1-Deficient Ovarian Cancer., PMID:26138335
Phosphorylation of ribosomal protein S6 confers PARP inhibitor resistance in BRCA1-deficient cancers., PMID:24831086
Construction of label-free electrochemical immunosensor on mesoporous carbon nanospheres for breast cancer susceptibility gene., PMID:23498687
Targeting BRCA1 localization to augment breast tumor sensitivity to poly(ADP-Ribose) polymerase inhibition., PMID:22962264
Three-dimensional imaging reveals the spatial separation of γH2AX-MDC1-53BP1 and RNF8-RNF168-BRCA1-A complexes at ionizing radiation-induced foci., PMID:22633816
The DeltaNp63 proteins are key allies of BRCA1 in the prevention of basal-like breast cancer., PMID:21363924
Association of loss of BRCA1 expression with centrosome aberration in human breast cancer., PMID:18813953
New drugs for ovarian cancer., PMID:18347558
Neurogenetics II: complex disorders., PMID:15834017
Characterization of several leukemia-associated antigens inducing humoral immune responses in acute and chronic myeloid leukemia., PMID:12800198
Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs., PMID:9497340