Catalog No.
RHP03101
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:500, IP: 1:100-1:200, WB: 1:500-1:1000
Target
CKLF-like MARVEL transmembrane domain-containing protein 6, Chemokine-like factor superfamily member 6, CKLFSF6, CMTM6
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9NX76
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4C56
Hsc70 promotes anti-tumor immunity by targeting PD-L1 for lysosomal degradation., PMID:38762492
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer., PMID:36627608
Construction of stable membranal CMTM6-PD-L1 full-length complex to evaluate the PD-1/PD-L1-CMTM6 interaction and develop anti-tumor anti-CMTM6 nanobody., PMID:36418428
CMTM6-Deficient Monocytes in ANCA-Associated Vasculitis Fail to Present the Immune Checkpoint PD-L1., PMID:34108971
Possible effects of chemokine-like factor-like MARVEL transmembrane domain-containing family on antiphospholipid syndrome., PMID:33813507
WEE1 inhibition reverses trastuzumab resistance in HER2-positive cancers., PMID:33723720
HuR up-regulates cell surface PD-L1 via stabilizing CMTM6 transcript in cancer., PMID:33649535
Expression Analysis of Canine CMTM6 and CMTM4 as Potential Regulators of the PD-L1 Protein in Canine Cancers., PMID:32596272
PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy., PMID:31053471
A novel 3p22.3 gene CMTM7 represses oncogenic EGFR signaling and inhibits cancer cell growth., PMID:23893243
For research use only. Not for human or drug use.
