Anti-SV2A Antibody (R4C31)

Catalog No.

RHP00901

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Tested applications

IHC: 1:50-1:250, IP: 1:100-1:200, WB: 1:500-1:1000

Target

SV2A, KIAA0736, Synaptic vesicle glycoprotein 2A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q7L0J3

Applications

IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4C31

The Critical Role of Biomarkers for Drug Development Targeting the Biology of Aging., PMID:37874093

Cross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes., PMID:33558502

PET imaging reveals early and progressive dopaminergic deficits after intra-striatal injection of preformed alpha-synuclein fibrils in rats., PMID:33352233

Nicotinic acetylcholine receptors regulate clustering, fusion and acidification of the rat brain synaptic vesicles., PMID:32474177

Engineered agrin attenuates the severity of experimental autoimmune myasthenia gravis., PMID:29193204

Brivaracetam as adjunctive therapy for the treatment of partial-onset seizures in patients with epilepsy: the current evidence base., PMID:27800023

Expression of messenger molecules and receptors in rat and human sphenopalatine ganglion indicating therapeutic targets., PMID:27587062

A Missense Mutation of the Gene Encoding Synaptic Vesicle Glycoprotein 2A (SV2A) Confers Seizure Susceptibility by Disrupting Amygdalar Synaptic GABA Release., PMID:27471467

Structural and Functional Interactions between Transient Receptor Potential Vanilloid Subfamily 1 and Botulinum Neurotoxin Serotype A., PMID:26745805

Modulation of inflammatory mediators in the trigeminal ganglion by botulinum neurotoxin type A: an organ culture study., PMID:26245187

Effects of acoustic trauma on the auditory system of the rat: The role of microglia., PMID:26162240

Expression of SV2 isoforms during rodent brain development., PMID:23937191

Amyloid precursor proteins are constituents of the presynaptic active zone., PMID:23815291

Identification of the SV2 protein receptor-binding site of botulinum neurotoxin type E., PMID:23621114

Single-axonal organelle analysis method reveals new protein-motor associations., PMID:23421679

Formation of Golgi-derived active zone precursor vesicles., PMID:22875941

Kindling-associated SV2A expression in hilar GABAergic interneurons of the mouse dentate gyrus., PMID:22266237

Localisation of SCN10A gene product Na(v)1.8 and novel pain-related ion channels in human heart., PMID:21646736

Neurites from PC12 cells are connected to each other by synapse-like structures., PMID:20698031

Distribution of the high-affinity binding site and intracellular target of botulinum toxin type A in the human bladder., PMID:20044204

Down-regulation synaptic vesicle protein 2A in the anterior temporal neocortex of patients with intractable epilepsy., PMID:19757204

Morphological differentiation of tau-green fluorescent protein embryonic stem cells into neurons after co-culture with auditory brain stem slices., PMID:19410633

Ultrastructural localization of active zone and synaptic vesicle proteins in a preassembled multi-vesicle transport aggregate., PMID:17977664

Distribution of Smoothened at hippocampal mossy fiber synapses., PMID:17435610

The adhesion molecule CHL1 regulates uncoating of clathrin-coated synaptic vesicles., PMID:17178404

Expression of Nav1.6 sodium channels by Schwann cells at neuromuscular junctions: role in the motor endplate disease phenotype., PMID:16078241

The transcription factor Bhlhb4 is required for rod bipolar cell maturation., PMID:15363390

Importance of vesicle proteins in the diagnosis and treatment of neuroendocrine tumors., PMID:15153446

Synaptic plasticity in mammalian photoreceptors prepared as sheets for retinal transplantation., PMID:14578425

Glucose uptake in PC12 cells: GLUT3 vesicle trafficking and fusion as revealed with a novel GLUT3-GFP fusion protein., PMID:12898536

Acetylcholinesterase promotes neurite elongation, synapse formation, and surface expression of AMPA receptors in hippocampal neurones., PMID:12799140

Differential distribution of synaptotagmin immunoreactivity among synapses in the goldfish, salamander, and mouse retina., PMID:12699082

The expression pattern and assembly profile of synaptic membrane proteins in ribbon synapses of the developing mouse retina., PMID:12596036

CLN3 protein is targeted to neuronal synapses but excluded from synaptic vesicles: new clues to Batten disease., PMID:11590129

Differential expression of GABA(B)R1 and GABA(B)R2 receptor immunoreactivity in neurochemically identified neurons of the rat neostriatum., PMID:11304711

The distribution of single P2x1-receptor clusters on smooth muscle cells in relation to nerve varicosities in the rat urinary bladder., PMID:11246492

Synaptic vesicle protein 2, A new neuroendocrine cell marker., PMID:11021834

Innervation of human adrenal gland and adrenal cortical lesions., PMID:10628800

SV2C is a synaptic vesicle protein with an unusually restricted localization: anatomy of a synaptic vesicle protein family., PMID:10625067

Myosin Va movements in normal and dilute-lethal axons provide support for a dual filament motor complex., PMID:10477758

SVOP, an evolutionarily conserved synaptic vesicle protein, suggests novel transport functions of synaptic vesicles., PMID:9801366

Synaptic vesicle protein SV2B, but not SV2A, is predominantly expressed and associated with microvesicles in rat pinealocytes., PMID:9648885

Immunocytochemical localization of synaptic proteins at vesicular organelles in PC12 cells., PMID:9239749

Identification in immunolocalization of a new class of proteoglycan (keratan sulfate) to the neuritic plaques of Alzheimer's disease., PMID:8620929

A phosphatidylinositol 4,5-bisphosphate-sensitive casein kinase I alpha associates with synaptic vesicles and phosphorylates a subset of vesicle proteins., PMID:7622570

Differential expression of synaptic vesicle protein 2 (SV2) isoforms., PMID:8083732

Conservation of the amino acid sequence of SV2, a transmembrane transporter in synaptic vesicles and endocrine cells., PMID:8299963

The synaptic vesicle proteins SV2, synaptotagmin and synaptophysin are sorted to separate cellular compartments in CHO fibroblasts., PMID:7901222

Hippocampal localization of 5'-nucleotidase as revealed by immunocytochemistry., PMID:8350982

Brain contains two forms of synaptic vesicle protein 2., PMID:7681585

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