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Anti-TRIB2 Antibody (R4B96)

Catalog #:   RHN98303 Specific References (21) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: ELISA, FCM, IF, WB
Accession: Q92519
Overview

Catalog No.

RHN98303

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, WB: 1:500-1:2000

Target

TRB2, Tribbles homolog 2, TRIB2, TRB-2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q92519

Applications

ELISA, FCM, IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4B96

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Jurkat cells using TRIB2 mouse mAb (green) and negative control (red).
  • Flow Cytometry
    Flow cytometric analysis of K562 cells using TRIB2 mouse mAb (green) and negative control (red).
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using TRIB2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
  • Western blot
    Western blot analysis using TRIB2 mouse mAb against Jurkat (1), MCF-7 (2), SW480 (3),and A375 (4) cell lysate.
References

Cell-based vs enzyme-linked immunosorbent assay for detection of anti-Tribbles homolog 2 autoantibodies in Chinese patients with narcolepsy., PMID:38318919

Identification of Diagnosis and Typological Characteristics Associated with Ferroptosis for Ulcerative Colitis via Bioinformatics and Machine Learning., PMID:37957905

The role of tribbles homolog 2 in vascular smooth muscle cell proliferation., PMID:36626273

Nanobodies identify an activated state of the TRIB2 pseudokinase., PMID:36108635

One-minute and green synthesis of magnetic iron oxide nanoparticles assisted by design of experiments and high energy ultrasound: Application to biosensing and immunoprecipitation., PMID:33812640

Narcolepsy, autoimmunity, and influenza A H1N1 vaccination., PMID:37469760

Functional effects of Tribbles homolog 2 in bovine ovarian granulosa cells†., PMID:32159216

Autoantibodies in Pandemrix®-induced narcolepsy: Nine candidate autoantigens fail the conformational autoantibody test., PMID:31328572

Anti-Tribbles Pseudokinase 2 (TRIB2)-Immunization Modulates Hypocretin/Orexin Neuronal Functions., PMID:28364459

A/H1N1 antibodies and TRIB2 autoantibodies in narcolepsy patients diagnosed in conjunction with the Pandemrix vaccination campaign in Sweden 2009-2010., PMID:24485154

Narcolepsy and H1N1 vaccination: a link?, PMID:24048081

Passive transfer of narcolepsy: anti-TRIB2 autoantibody positive patient IgG causes hypothalamic orexin neuron loss and sleep attacks in mice., PMID:23834844

TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function., PMID:23769673

Increased childhood incidence of narcolepsy in western Sweden after H1N1 influenza vaccination., PMID:23486871

Narcolepsy in the pediatric population., PMID:22213222

Anti-Tribbles homolog 2 autoantibodies in Japanese patients with narcolepsy., PMID:20614847

Anti-Tribbles homolog 2 (TRIB2) autoantibodies in narcolepsy are associated with recent onset of cataplexy., PMID:20614846

The trouble with Tribbles: do antibodies against TRIB2 cause narcolepsy?, PMID:20614841

Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients., PMID:20160349

Tribbles-1 as a novel biomarker of chronic antibody-mediated rejection., PMID:18369086

Identification of tribbles homolog 2 as an autoantigen in autoimmune uveitis by phage display., PMID:15950723

Datasheet

Document Download

Anti-TRIB2 Antibody (R4B96).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-TRIB2 Antibody (R4B96) [RHN98303]
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