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Anti-BRIP1 Antibody (R4B84)

Catalog #:   RHN97702 Specific References (9) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IHC
Accession: Q9BX63
Overview

Catalog No.

RHN97702

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000

Target

ATP-dependent RNA helicase BRIP1, BRCA1-associated C-terminal helicase 1, BACH1, BRCA1-interacting protein 1, Protein FACJ, BRIP1, Fanconi anemia group J protein, FANCJ, BRCA1-interacting protein C-terminal helicase 1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9BX63

Applications

ELISA, FCM, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4B84

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using BRIP1 mouse mAb (green) and negative control (red).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using BRIP1 mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using BRIP1 mouse mAb with DAB staining.
References

The DNA helicase FANCJ (BRIP1) functions in double strand break repair processing, but not crossover formation during prophase I of meiosis in male mice., PMID:38377115

The DNA helicase FANCJ (BRIP1) functions in Double Strand Break repair processing, but not crossover formation during Prophase I of meiosis in male mice., PMID:37873301

Genomic analysis of plasma circulating tumor DNA in patients with heavily pretreated HER2 + metastatic breast cancer., PMID:37336919

Homologous Recombination Repair Gene Mutations to Predict Olaparib Plus Bevacizumab Efficacy in the First-Line Ovarian Cancer PAOLA-1/ENGOT-ov25 Trial., PMID:36716415

Leptomeningeal disease in BRIP1-mutated pancreatic adenocarcinoma., PMID:35675963

Mutations in DNA Repair Genes and Clinical Outcomes of Patients With Metastatic Colorectal Cancer Receiving Oxaliplatin or Irinotecan-containing Regimens., PMID:33298767

Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma., PMID:32653773

[Hereditary breast carcinomas pathologist's perspective]., PMID:32241645

FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells., PMID:21605288

Datasheet

Document Download

Anti-BRIP1 Antibody (R4B84).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Anti-BRIP1 Antibody (R4B84) [RHN97702]
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