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Anti-KMT2C Antibody (R4B75)

Catalog #:   RHN97202 Specific References (18) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IF, IHC
Accession: Q8NEZ4
Overview

Catalog No.

RHN97202

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000

Target

MLL3, Homologous to ALR protein, Myeloid/lymphoid or mixed-lineage leukemia protein 3, HALR, Lysine N-methyltransferase 2C, KIAA1506, KMT2C, Histone-lysine N-methyltransferase 2C

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8NEZ4

Applications

ELISA, FCM, IF, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4B75

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using KMT2C mouse mAb (green) and negative control (red).
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using KMT2C mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using KMT2C mouse mAb with DAB staining.
References

Association of Fc gamma-binding protein rs1464897604 polymorphism with bronchiolitis obliterans syndrome in lung transplant recipients., PMID:40441397

Epidemiological and genetic factors affecting severe epizootic hemorrhagic disease in Spanish Holstein cattle during the Southern Europe outbreak of 2023., PMID:39788199

A Rare Case of a Malignant Proliferating Trichilemmal Tumor: A Molecular Study Harboring Potential Therapeutic Significance and a Review of Literature., PMID:39727620

Mutational Landscape of Bone Marrow CD19 and CD138 Cells in Waldenström Macroglobulinemia (WM) and IgM Monoclonal Gammopathy of Undetermined Significance (IgM MGUS)., PMID:39711167

Feasibility of Circulating Tumor DNA Analysis in Patients with Follicular Lymphoma., PMID:38228081

The landscape of genetic alterations of UVB-induced skin tumors in DNA repair-deficient mice., PMID:35751582

Clinicopathologic and Genomic Features in Triple-Negative Breast Cancer Between Special and No-Special Morphologic Pattern., PMID:35402236

KMT2C is a Potential Biomarker of Anti-PD-1 Treatment Response in Metastatic Melanoma., PMID:35345335

Advances in the Treatment of Hairy Cell Leukemia Variant., PMID:35178674

TET2 coactivates gene expression through demethylation of enhancers., PMID:30417100

MLL3 enhances the transcription of PD-L1 and regulates anti-tumor immunity., PMID:30385408

PD-1 inhibition in congenital pigment synthesizing metastatic melanoma., PMID:28675691

Subsets of Visceral Adipose Tissue Nuclei with Distinct Levels of 5-Hydroxymethylcytosine., PMID:27171244

A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex., PMID:26744420

Genetic Landscapes of Relapsed and Refractory Diffuse Large B-Cell Lymphomas., PMID:26647218

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development., PMID:24619213

Immunology. Double TIP-ping., PMID:20724627

Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation., PMID:19221051

Datasheet

Document Download

Anti-KMT2C Antibody (R4B75).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-KMT2C Antibody (R4B75) [RHN97202]
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