Catalog No.
RHN95801
Species reactivity
Human, Mouse
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, WB: 1:500-1:2000
Target
Krueppel-like factor 2, KLF2, Lung krueppel-like factor, LKLF
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y5W3
Applications
ELISA, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4B51
KLF2 inhibition expands tumor-resident T cells and enhances tumor immunity., PMID:40162209
KLF2 expression in IgG plasma cells at their induction site regulates the migration program., PMID:39976598
KLF2 controls the apoptosis of neutrophils and is associated with disease activity of systemic lupus erythematosus., PMID:39702240
Endothelial γ-protocadherins inhibit KLF2 and KLF4 to promote atherosclerosis., PMID:39232138
A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling., PMID:39196179
Gamma protocadherins in vascular endothelial cells inhibit Klf2/4 to promote atherosclerosis., PMID:38293157
Dynamic altruistic cooperation within breast tumors., PMID:38093346
PRC2 mediated KLF2 down regulation: a therapeutic and diagnostic axis during tumor progression., PMID:37807067
Krüppel-like factor 2: a central regulator of B cell differentiation and plasma cell homing., PMID:37251374
S1PR1-dependent migration of ILC3s from intestinal tissue to the heart in a mouse model of viral myocarditis., PMID:37141387
Endothelial Cell Markers Are Inferior to Vascular Smooth Muscle Cells Markers in Staining Vasa Vasorum and Are Non-Specific for Distinct Endothelial Cell Lineages in Clinical Samples., PMID:36768296
A targetable pathway in neutrophils mitigates both arterial and venous thrombosis., PMID:36044595
RNA Sequencing Reveals Beneficial Effects of Atorvastatin on Endothelial Cells in Acute Kawasaki Disease., PMID:35861833
Krüppel-like factor 2 controls IgA plasma cell compartmentalization and IgA responses., PMID:35347229
Nanoliposome C6-Ceramide in combination with anti-CTLA4 antibody improves anti-tumor immunity in hepatocellular cancer., PMID:35294071
Nano delivery of simvastatin targets liver sinusoidal endothelial cells to remodel tumor microenvironment for hepatocellular carcinoma., PMID:34983554
IL-21 Promotes Intestinal Memory IgA Responses., PMID:32859726
Synovial fluid CD69+CD8+ T cells with tissue-resident phenotype mediate perforin-dependent citrullination in rheumatoid arthritis., PMID:32528679
The EGFL7-ITGB3-KLF2 axis enhances survival of multiple myeloma in preclinical models., PMID:32191808
Activation of the IL-1β/KLF2/HSPH1 pathway promotes STAT3 phosphorylation in alveolar macrophages during LPS-induced acute lung injury., PMID:32091104
Coxsackievirus and adenovirus receptor mediates the responses of endothelial cells to fluid shear stress., PMID:31776326
Glucagon-like peptide-1 receptor agonist dulaglutide prevents ox-LDL-induced adhesion of monocytes to human endothelial cells: An implication in the treatment of atherosclerosis., PMID:31630078
Therapeutic Intranasal Vaccine HB-ATV-8 Prevents Atherogenesis and Non-alcoholic Fatty Liver Disease in a Pig Model of Atherosclerosis., PMID:30792163
PI3K Orchestrates T Follicular Helper Cell Differentiation in a Context Dependent Manner: Implications for Autoimmunity., PMID:30666254
Function of Krüppel‑like factor 2 in the shear stress‑induced cell differentiation of endothelial progenitor cells to endothelial cells., PMID:30628700
[New molecular pathological strategies for malignant iris tumors]., PMID:30623224
Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice., PMID:30442679
Identification of Basic Fibroblast Growth Factor as the Dominant Protector of Laminar Shear Medium from the Modified Shear Device in Tumor Necrosis Factor-α Induced Endothelial Dysfunction., PMID:29354066
A gene is known by the company it keeps: enrichment of TNFAIP3 gene aberrations in MALT lymphomas expressing IGHV4-34 antigen receptors., PMID:28892161
Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1., PMID:28394372
Genomics of Hairy Cell Leukemia., PMID:28297625
Molecular identification and functional analysis of KLF2 in Plecoglossus altivelis (ayu): It's regulatory role in monocyte/macrophage activation., PMID:28130078
Regulators of Tfh Cell Differentiation., PMID:27933060
miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity., PMID:27791035
BRAF V600E mutation in hairy cell leukemia: from bench to bedside., PMID:27554081
Reduced Krüppel-Like Factor 2 Aggravates Glomerular Endothelial Cell Injury and Kidney Disease in Mice with Unilateral Nephrectomy., PMID:27317905
Early Loss of Splenic Tfh Cells in SIV-Infected Rhesus Macaques., PMID:26640894
The artificial loss of Runx1 reduces the expression of quiescence-associated transcription factors in CD4(+) T lymphocytes., PMID:26350416
Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing., PMID:25779943
Dopamine and T cells: dopamine receptors and potent effects on T cells, dopamine production in T cells, and abnormalities in the dopaminergic system in T cells in autoimmune, neurological and psychiatric diseases., PMID:25728499
KLF2--a negative regulator of pre-B cell clonal expansion and B cell activation., PMID:24874925
Derivation of naive human embryonic stem cells., PMID:24623855
Tgfβ/Alk5 signaling is required for shear stress induced klf2 expression in embryonic endothelial cells., PMID:21604321
Endothelial cell activation by antiphospholipid antibodies is modulated by Kruppel-like transcription factors., PMID:21482710
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation., PMID:21460836
CD4+CD25+Foxp3+ regulatory T cells protect the proinflammatory activation of human umbilical vein endothelial cells., PMID:20930173
Ultraviolet A regulates adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells via up-regulation of Kruppel-like factor 2., PMID:20693579
Natural killer T cells constitutively expressing the interleukin-2 receptor α chain early in life are primed to respond to lower antigenic stimulation., PMID:20545784
Neural crest-derived pericytes promote egress of mature thymocytes at the corticomedullary junction., PMID:20413455
KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium., PMID:20032497
For research use only. Not for human or drug use.
