Catalog No.
RHN95202
Species reactivity
Human, Mouse
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
FHR-5, Complement factor H-related protein 5, CFHL5, CFHR5, FHR5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9BXR6
Applications
ELISA, FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4B41
Complement factor H-related protein 5 alleviates joint inflammation and osteoclast differentiation by disrupting RANK-JNK signaling in collagen antibody-induced arthritis mouse model., PMID:39461285
Complement dysregulation associated with a genetic variant in factor H-related protein 5 in atypical hemolytic uremic syndrome., PMID:37955705
Evaluation of the significance of complement-related genes mutations in atypical postinfectious glomerulonephritis: a pilot study., PMID:37845399
Pathogenic Neisseria Bind the Complement Protein CFHR5 via Outer Membrane Porins., PMID:36194022
Blockade of the Terminal Complement Cascade Using Ravulizumab in a Pediatric Patient With Anti-complement Factor H Autoantibody-Associated aHUS: A Case Report and Literature Review., PMID:34912617
FHR-5 Serum Levels and CFHR5 Genetic Variations in Patients With Immune Complex-Mediated Membranoproliferative Glomerulonephritis and C3-Glomerulopathy., PMID:34566977
Complement and kidney disease, new insights., PMID:33767058
A Narrative Review on C3 Glomerulopathy: A Rare Renal Disease., PMID:31947692
Outcome of C3 glomerulopathy patients: largest single-centre experience from South Asia., PMID:31820418
The clinical significance of plasma CFHR 1-5 in lupus nephropathy., PMID:30975435
Outcome of membranoproliferative glomerulonephritis and C3-glomerulopathy in children and adolescents., PMID:30238151
Dominant C3 glomerulopathy: new roles for an old actor in renal pathology., PMID:29151252
Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma., PMID:29093712
Clinico-pathologic spectrum of C3 glomerulopathy-an Indian experience., PMID:25889427
[C3 glomerulopathy]., PMID:24671835
A novel CFHR5 mutation associated with C3 glomerulonephritis in a Turkish girl., PMID:24536001
Germline variation in complement genes and event-free survival in follicular and diffuse large B-cell lymphoma., PMID:22718493
Eculizumab for dense deposit disease and C3 glomerulonephritis., PMID:22403278
Familial C3 glomerulopathy associated with CFHR5 mutations: clinical characteristics of 91 patients in 16 pedigrees., PMID:21566112
Complement and glomerular disease: new insights., PMID:21422921
A complement to kidney disease: CFHR5 nephropathy., PMID:20800272
Factor H-related protein-5: a novel component of human glomerular immune deposits., PMID:11774097
For research use only. Not for human or drug use.
