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Anti-KDM5B Antibody (R4B30)

Catalog #:   RHN94601 Specific References (13) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM
Accession: Q9UGL1
Overview

Catalog No.

RHN94601

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400

Target

[histone H3]-trimethyl-L-lysine(4) demethylase 5B, Lysine-specific demethylase 5B, Cancer/testis antigen 31, JARID1B, CT31, RBBP2H1, Jumonji/ARID domain-containing protein 1B, PLU-1, Retinoblastoma-binding protein 2 homolog 1, RBP2-H1, PLU1, Histone demethylase JARID1B, KDM5B

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9UGL1

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4B30

Data Image
  • Flow Cytometry
    Flow cytometric analysis of MCF-7 cells using KDM5B mouse mAb (green) and negative control (red).
References

Overcoming of Radioresistance in Non-small Cell Lung Cancer by microRNA-320a Through HIF1α-Suppression Mediated Methylation of PTEN., PMID:33304897

KDM5B demethylates H3K4 to recruit XRCC1 and promote chemoresistance., PMID:29989047

Studies on the Interaction of the Histone Demethylase KDM5B with Tricarboxylic Acid Cycle Intermediates., PMID:28827149

Real-time quantification of single RNA translation dynamics in living cells., PMID:27313040

Inhibition of the histone demethylase Kdm5b promotes neurogenesis and derepresses Reln (reelin) in neural stem cells from the adult subventricular zone of mice., PMID:26739753

Structure and binding properties of a cameloid nanobody raised against KDM5B., PMID:26457512

Assessment of melanoma-initiating cell markers and conventional parameters in sentinel lymph nodes of malignant melanoma., PMID:25703167

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development., PMID:24619213

Melanoma stem cells in experimental melanoma are killed by radioimmunotherapy., PMID:23146306

JARID1B protein expression and prognostic implications in uveal melanoma., PMID:22669717

Jarid1b targets genes regulating development and is involved in neural differentiation., PMID:22020125

PLU-1, a transcriptional repressor and putative testis-cancer antigen, has a specific expression and localisation pattern during meiosis., PMID:14579128

A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer., PMID:10336460

Datasheet

Document Download

Anti-KDM5B Antibody (R4B30).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-KDM5B Antibody (R4B30) [RHN94601]
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