Catalog No.
RHN93501
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
ATP-binding cassette sub-family G member 5, ABCG5, Sterolin-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9H222
Applications
ELISA, FCM, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4B10
Structural bioinformatics studies of six human ABC transporters and their AlphaFold2-predicted water-soluble QTY variants., PMID:38577032
Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion., PMID:35922515
Interrupting tumor necrosis factor-alpha signaling prevents parenteral nutrition-associated cholestasis in mice., PMID:34664730
Metformin, Macrophage Dysfunction and Atherosclerosis., PMID:34163481
Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies., PMID:33953337
Sitosterolemia Exhibiting Severe Hypercholesterolemia with Tendon Xanthomas Due to Compound Heterozygous ABCG5 Gene Mutations Treated with Ezetimibe and Alirocumab., PMID:32713907
CCN family member 1 deregulates cholesterol metabolism and aggravates atherosclerosis., PMID:30347516
From lipid locus to drug target through human genomics., PMID:29800275
Amelioration of non-alcoholic fatty liver disease with NPC1L1-targeted IgY or n-3 polyunsaturated fatty acids in mice., PMID:27923447
ATP-binding cassette sterol transporters are differentially expressed in normal and diseased human gallbladder., PMID:23179156
Purification and reconstitution of sterol transfer by native mouse ABCG5 and ABCG8., PMID:18402465
Expression, localization, and inducibility by bile acids of hepatobiliary transporters in the new polarized rat hepatic cell lines, Can 3-1 and Can 10., PMID:17909858
Localization of ABCG5 and ABCG8 proteins in human liver, gall bladder and intestine., PMID:15383151
ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion., PMID:14504269
For research use only. Not for human or drug use.
