Catalog No.
RHN92001
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IF: 1:200-1:1000
Target
HAS1, HuHAS1, Hyaluronate synthase 1, HA synthase 1, Hyaluronan synthase 1, Hyaluronic acid synthase 1, HAS
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q92839
Applications
IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4A87
Osteopontin (OPN) alleviates the progression of osteoarthritis by promoting the anabolism of chondrocytes., PMID:37397527
Modulation of hyaluronan synthases and involvement of T cell-derived hyaluronan in autoimmune responses to transplanted islets., PMID:33718858
Mechanistic Insight on the Interaction between OPN and Integrin ανβ3 in Osteoarthritis., PMID:33134374
Effect of ligand-receptor interaction of osteopontin-CD44 on the expression of hyaluronic acid in human knee osteoarthritic chondrocytes in vitro., PMID:33051414
Effects of Apigenin on RBL-2H3, RAW264.7, and HaCaT Cells: Anti-Allergic, Anti-Inflammatory, and Skin-Protective Activities., PMID:32610574
Tau Pathology Promotes the Reorganization of the Extracellular Matrix and Inhibits the Formation of Perineuronal Nets by Regulating the Expression and the Distribution of Hyaluronic Acid Synthases., PMID:28234253
Elevated Serum Tetrac in Graves Disease: Potential Pathogenic Role in Thyroid-Associated Ophthalmopathy., PMID:27768856
Distribution and characteristics of slow-cycling cells in rat vocal folds., PMID:26845229
The reciprocal association between mammographic breast density, hyaluronan synthesis and patient outcome., PMID:26362804
Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3., PMID:25795779
Interleukin-6-dependent phenotypic modulation of cardiac fibroblasts after acute myocardial infarction., PMID:25236954
Beneficial effects of melatonin on bovine oocytes maturation: a mechanistic approach., PMID:25070516
Hyaluronan synthases (HAS1-3) in stromal and malignant cells correlate with breast cancer grade and predict patient survival., PMID:24337597
Hyaluronan synthase 1 (HAS1) produces a cytokine-and glucose-inducible, CD44-dependent cell surface coat., PMID:24099991
Tissue distribution and subcellular localization of hyaluronan synthase isoenzymes., PMID:24057227
Critical role of hyaluronidase-2 during preimplantation embryo development., PMID:23625939
Cell surface expression of hyaluronan on human ovarian cancer cells inversely correlates with their adhesion to peritoneal mesothelial cells., PMID:22392500
Therapeutic potential of hyaluronan oligosaccharides for bone metastasis of breast cancer., PMID:21913222
Transforming growth factor-beta 1 in adipose derived stem cells conditioned medium is a dominant paracrine mediator determines hyaluronic acid and collagen expression profile., PMID:21203839
Fibroblast growth factor-2 stimulates directed migration of periodontal ligament cells via PI3K/AKT signaling and CD44/hyaluronan interaction., PMID:20857427
Effects of thyrotropin and thyrotropin-receptor-stimulating Graves' disease immunoglobulin G on cyclic adenosine monophosphate and hyaluronan production in nondifferentiated orbital fibroblasts of Graves' ophthalmopathy patients., PMID:20384487
Thyrotropin receptor activation increases hyaluronan production in preadipocyte fibroblasts: contributory role in hyaluronan accumulation in thyroid dysfunction., PMID:19633293
bFGF induces changes in hyaluronan synthase and hyaluronidase isoform expression and modulates the migration capacity of fibrosarcoma cells., PMID:19577615
Expression of hyaluronan synthase 1 and distribution of hyaluronan during follicular atresia in pig ovaries., PMID:18923162
An enzyme capture assay for analysis of active hyaluronan synthases., PMID:17904513
Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB., PMID:17324121
Secretory products of breast cancer cells upregulate hyaluronan production in a human osteoblast cell line., PMID:16642399
Expression patterns of hyaluronan, hyaluronan synthases and hyaluronidases indicate a role for hyaluronan in the progression of endometrial cancer., PMID:15936804
Role of hyaluronan and hyaluronan synthase in endometrial cancer., PMID:15870928
Hyaluronan synthase expression in pleural malignant mesotheliomas., PMID:15731923
Hyaluronan synthase expression in ovarian cancer., PMID:15375493
Hyaluronan facilitates invasion of colon carcinoma cells in vitro via interaction with CD44., PMID:15231668
Hyaluronan synthases in normal and regenerating joint cartilage., PMID:12649587
Expression of hyaluronan synthases and CD44 messenger RNAs in porcine cumulus-oocyte complexes during in vitro maturation., PMID:11870078
The role of CD44 during CD40 ligand-induced dendritic cell clustering and maturation., PMID:11698490
Reticular erythematous mucinosis syndrome with an infiltration of factor XIIIa+ and hyaluronan synthase 2+ dermal dendrocytes., PMID:11453924
Expression of human hyaluronan synthases in response to external stimuli., PMID:10794710
Increased synthesis of hyaluronate enhances motility of human melanoma cells., PMID:10594733
HMC-1 mast cells activate human orbital fibroblasts in coculture: evidence for up-regulation of prostaglandin E2 and hyaluronan synthesis., PMID:10433207
The active streptococcal hyaluronan synthases (HASs) contain a single HAS monomer and multiple cardiolipin molecules., PMID:9748290
Characterization of hyaluronan synthase from a human glioma cell line., PMID:9555098
Molecular cloning, expression, and characterization of the authentic hyaluronan synthase from group C Streptococcus equisimilis., PMID:9405467
Homologs of the Xenopus developmental gene DG42 are present in zebrafish and mouse and are involved in the synthesis of Nod-like chitin oligosaccharides during early embryogenesis., PMID:8643441
Antibodies against proteins of streptococcal hyaluronate synthase bind to human fibroblasts and are present in patients with rheumatic fever., PMID:7591991
The formation of human synovial joint cavities: a possible role for hyaluronan and CD44 in altered interzone cohesion., PMID:7525525
Immunochemical confirmation of the primary structure of streptococcal hyaluronan synthase and synthesis of high molecular weight product by the recombinant enzyme., PMID:8049203
CD44 variant isoforms are preferentially expressed in basal epithelial of non-malignant human fetal and adult tissues., PMID:7520892
Hyaluronan synthase immunoreactivity in the anterior segment of the primate eye., PMID:8339945
The hyaluronate synthase from a eukaryotic cell line., PMID:8457208
Immunohistochemical localization of hyaluronan synthase in cornea and conjunctive of cynomolgus monkey., PMID:1521573
For research use only. Not for human or drug use.
