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Anti-FOXA2 Antibody (R4A79)

Catalog #:   RHN91401 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC, WB
Accession: Q9Y261
Overview

Catalog No.

RHN91401

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

TCF-3B, HNF-3-beta, HNF3B, Transcription factor 3B, TCF3B, Forkhead box protein A2, Hepatocyte nuclear factor 3-beta, HNF-3B, FOXA2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9Y261

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4A79

Data Image
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human colon cancer (A), gastric cancer (B) and rectal cancer (C) tissues using FOXA2 mouse mAb with DAB staining.
  • Western blot
    Western blot analysis using FOXA2 mouse mAb against A549 (1) cell lysate.
References

FOXA2 promotes metastatic competence in small cell lung cancer., PMID:40419484

Identification of Lineage-specific Transcriptional Factor-defined Molecular Subtypes in Small Cell Bladder Cancer., PMID:37380560

Primary mediastinal germ cell tumours: an immunohistochemical and molecular diagnostic approach., PMID:34506648

Generation of pancreatic progenitors from human pluripotent stem cells by small molecules., PMID:34450037

MRE11 promotes oral cancer progression through RUNX2/CXCR4/AKT/FOXA2 signaling in a nuclease-independent manner., PMID:33927349

Estrogen Receptor, Inflammatory, and FOXO Transcription Factors Regulate Expression of Myasthenia Gravis-Associated Circulating microRNAs., PMID:32153563

Angiopoietin-1 accelerates Alzheimer's disease via FOXA2/PEN2/APP pathway in APP/PS1 mice., PMID:32061671

Generation of functional dopaminergic neurons from human spermatogonial stem cells to rescue parkinsonian phenotypes., PMID:31248447

Exome sequencing identifies a de novo FOXA2 variant in a patient with syndromic diabetes., PMID:30684292

Chemical Cocktails Enable Hepatic Reprogramming of Mouse Fibroblasts with a Single Transcription Factor., PMID:28757167

Purification of Definitive Endoderm Generated from Pluripotent Stem Cells by Magnetic Cell Sorting., PMID:28152181

Defined three-dimensional culture conditions mediate efficient induction of definitive endoderm lineage from human umbilical cord Wharton's jelly mesenchymal stem cells., PMID:27852316

Direct induction of hepatocyte-like cells from immortalized human bone marrow mesenchymal stem cells by overexpression of HNF4α., PMID:27501760

Conditional pulmonary over-expression of Claudin 6 during embryogenesis delays lung morphogenesis., PMID:26198145

Direct conversion of human fibroblasts into dopaminergic neural progenitor-like cells using TAT-mediated protein transduction of recombinant factors., PMID:25767075

Epigenetic regulation contributes to urocortin-enhanced midbrain dopaminergic neuron differentiation., PMID:25641682

Sox17 regulates insulin secretion in the normal and pathologic mouse β cell., PMID:25144761

Selection Based on FOXA2 Expression Is Not Sufficient to Enrich for Dopamine Neurons From Human Pluripotent Stem Cells., PMID:25024431

Laminin 411 acts as a potent inducer of umbilical cord mesenchymal stem cell differentiation into insulin-producing cells., PMID:24885418

Novel mechanism of transcriptional repression of the human ATP binding cassette transporter A1 gene in hepatic cells by the winged helix/forkhead box transcription factor A2., PMID:24807696

Pulmonary endoderm, second heart field and the morphogenesis of distal outflow tract in mouse embryonic heart., PMID:24697670

Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation., PMID:24496614

Stem cell profiling in head and neck cancer reveals an Oct-4 expressing subpopulation with properties of chemoresistance., PMID:24387977

Pyocyanin-induced mucin production is associated with redox modification of FOXA2., PMID:23915402

Effect of a matrigel sandwich on endodermal differentiation of human embryonic stem cells., PMID:23719997

Secreted cerberus1 as a marker for quantification of definitive endoderm differentiation of the pluripotent stem cells., PMID:23717584

Characterization of an apparently novel β-cell line-enriched 80-88 kDa transcriptional activator of the MafA and Pdx1 genes., PMID:23269676

The transcription factor Myt3 acts as a pro-survival factor in β-cells., PMID:23236509

Hepatic differentiation of human embryonic stem cells on growth factor-containing surfaces., PMID:23086797

Tonsil-derived mesenchymal stromal cells: evaluation of biologic, immunologic and genetic factors for successful banking., PMID:22900958

Induction and selection of Sox17-expressing endoderm cells generated from murine embryonic stem cells., PMID:22123608

Epigenetic regulation of the transcription factor Foxa2 directs differential elafin expression in melanocytes and melanoma cells., PMID:21466784

DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma., PMID:21281797

Interleukin-13 induces mucin 5AC production involving STAT6/SPDEF in human airway epithelial cells., PMID:21275604

Intestinal lineage commitment of embryonic stem cells., PMID:20934799

Characterization of axon guidance cue sensitivity of human embryonic stem cell-derived dopaminergic neurons., PMID:20637284

Foxa2 (HNF-3beta) regulates expression of hepatotrophic factor ALR in liver cells., PMID:20382118

MafA promotes the reprogramming of placenta-derived multipotent stem cells into pancreatic islets-like and insulin+ cells., PMID:20158571

Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors., PMID:20043076

Generation of monoclonal antibodies specific for cell surface molecules expressed on early mouse endoderm., PMID:19522011

Cellular and molecular origin of circumpapillary dysgenesis of the pigment epithelium., PMID:19410955

Human embryonic stem cells hemangioblast express HLA-antigens., PMID:19386101

Chronic intermittent mechanical stress increases MUC5AC protein expression., PMID:19168703

Signals from the embryonic mouse pancreas induce differentiation of human embryonic stem cells into insulin-producing beta-cell-like cells., PMID:16186387

Transcriptional networks in the liver: hepatocyte nuclear factor 6 function is largely independent of Foxa2., PMID:16055718

Expression and role of Foxa proteins in prostate cancer., PMID:16001449

Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues., PMID:15567715

Expression of Foxa transcription factors in the developing and adult murine prostate., PMID:15389796

Forkhead box A2 transcription factor is expressed in all types of neuroendocrine lung tumors., PMID:15138929

[The expression of human specific proteins in liver tissue of chimeric goats engrafted with human hematopoitic stem cells]., PMID:12126514

Datasheet

Document Download

Anti-FOXA2 Antibody (R4A79).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-FOXA2 Antibody (R4A79) [RHN91401]
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