Catalog No.
RHN90801
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IF: 1:200-1:1000, IHC: 1:200-1:1000
Target
LR11, Sorting protein-related receptor containing LDLR class A repeats, LDLR relative with 11 ligand-binding repeats, Low-density lipoprotein receptor relative with 11 ligand-binding repeats, SORL1, SorLA-1, SorLA, C11orf32, Sortilin-related receptor
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q92673
Applications
IF, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4A72
SORL1-Mediated EGFR and FGFR4 Regulation Enhances Chemoresistance in Ovarian Cancer., PMID:39858026
Genomics of Alzheimer's disease implicates the innate and adaptive immune systems., PMID:34708251
The Association Between Sortilin and Inflammation in Patients with Coronary Heart Disease., PMID:32104044
SORLA regulates endosomal trafficking and oncogenic fitness of HER2., PMID:31138794
Sortilin-related receptor CNS expressed 2 (SorCS2) is localized to Bunina bodies in amyotrophic lateral sclerosis., PMID:26420026
Tetraspanin CD9 modulates ADAM17-mediated shedding of LR11 in leukocytes., PMID:24699135
Known players, new interplay in atherogenesis: Chronic shear stress and carbamylated-LDL induce and modulate expression of atherogenic LR11 in human coronary artery endothelium., PMID:24284991
The soluble form of LR11 protein is a regulator of hypoxia-induced, urokinase-type plasminogen activator receptor (uPAR)-mediated adhesion of immature hematological cells., PMID:23486467
[Novel biomarker for pathological immature cells--soluble form of LR11]., PMID:22774576
Protein kinase C and rho activated coiled coil protein kinase 2 (ROCK2) modulate Alzheimer's APP metabolism and phosphorylation of the Vps10-domain protein, SorL1., PMID:21192821
Development of an immunoassay for the quantification of soluble LR11, a circulating marker of atherosclerosis., PMID:19661140
A secreted soluble form of LR11, specifically expressed in intimal smooth muscle cells, accelerates formation of lipid-laden macrophages., PMID:17332490
LR11, an LDL receptor gene family member, is a novel regulator of smooth muscle cell migration., PMID:14764453
A protocol for isolation and biochemical characterization of stigmoid bodies from rat brain., PMID:12763227
Stigmoid bodies contain type I receptor proteins SorLA/LR11 and sortilin: new perspectives on their function., PMID:12754295
SorLA, a member of the LDL receptor family, is expressed in the collecting duct of the murine kidney., PMID:12271354
Enhanced expression of the LDL receptor family member LR11 increases migration of smooth muscle cells in vitro., PMID:11956127
Neuronal localization of a novel mosaic apolipoprotein E receptor, LR11, in rat and human brain., PMID:10375696
Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein., PMID:8940146
For research use only. Not for human or drug use.
