Catalog No.
RHN90601
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
RNF88, RING-type E3 ubiquitin transferase TRIM5, RING finger protein 88, TRIM5, Tripartite motif-containing protein 5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9C035
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4A70
TRIM5 Promotes Systemic Lupus Erythematosus Through CD4(+) T Cells and Macrophage., PMID:37614552
Knockdown of TRIM5α or TRIM11 increases lentiviral vector transduction efficiency of human Muller cells., PMID:33440192
Restriction Factor Expression in Vertically Infected Children Living With HIV-1., PMID:33395209
A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases., PMID:31582740
HIV-1 capsids from B27/B57+ elite controllers escape Mx2 but are targeted by TRIM5α, leading to the induction of an antiviral state., PMID:30419009
Host Restriction Factors APOBEC3G/3F and Other Interferon-Related Gene Expressions Affect Early HIV-1 Infection in Northern Pig-Tailed Macaque (Macaca leonina)., PMID:30210504
Do Human Endogenous Retroviruses Contribute to Multiple Sclerosis, and if So, How?, PMID:30047100
High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques., PMID:27683750
A pilot study on commonality and specificity of copy number variants in schizophrenia and bipolar disorder., PMID:27244233
Strong, but Age-Dependent, Protection Elicited by a Deoxyribonucleic Acid/Modified Vaccinia Ankara Simian Immunodeficiency Virus Vaccine., PMID:27006959
An overview of the lagomorph immune system and its genetic diversity., PMID:26399242
Preclinical Assessment of Mutant Human TRIM5α as an Anti-HIV-1 Transgene., PMID:26076730
Using antiubiquitin antibodies to probe the ubiquitination state within rhTRIM5α cytoplasmic bodies., PMID:23799296
Tactics used by HIV-1 to evade host innate, adaptive, and intrinsic immunities., PMID:23786957
Associations between polymorphisms in the antiviral TRIM genes and measles vaccine immunity., PMID:23416095
Innate immune sensing of HIV-1 by dendritic cells., PMID:23084911
Lentiviral gene therapy against human immunodeficiency virus type 1, using a novel human TRIM21-cyclophilin A restriction factor., PMID:22909012
Genetic polymorphisms associated with anti-malarial antibody levels in a low and unstable malaria transmission area in southern Sri Lanka., PMID:22905743
Structure of the rhesus monkey TRIM5α PRYSPRY domain, the HIV capsid recognition module., PMID:22847415
Intracellular detection of differential APOBEC3G, TRIM5alpha, and LEDGF/p75 protein expression in peripheral blood by flow cytometry., PMID:21784078
Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys., PMID:21543722
Vif substitution enables persistent infection of pig-tailed macaques by human immunodeficiency virus type 1., PMID:21289128
Extraordinary antigenicity of the human Ro52 autoantigen., PMID:20407604
Polymorphisms in the vitamin A receptor and innate immunity genes influence the antibody response to rubella vaccination., PMID:20001730
HIV and SIV infection: the role of cellular restriction and immune responses in viral replication and pathogenesis., PMID:19400864
A retrovirus restriction factor TRIM5alpha is transcriptionally regulated by interferons., PMID:16289103
For research use only. Not for human or drug use.
