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Anti-ING1 Antibody (R4A34)

Catalog #:   RHN79503 Specific References (26) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: IP, WB
Accession: Q9UK53
Overview

Catalog No.

RHN79503

Species reactivity

Human, Mouse

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

IP: 1:100-1:200, WB: 1:500-1:1000

Target

ING1, Inhibitor of growth protein 1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9UK53

Applications

IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4A34

Data Image
  • Immunoprecipitation
    Lane 1: Mouse testis tissue lysate ; Lane 2: ING1 immunoprecipitated from mouse testis tissue lysate by RHN79503;Lane 3: The same as Lane 2 but use IgG isotype control antibody ;Result: RHN79503 can immunoprecipitate ING1;
  • Western blot
    Western blot analysis using ING1 mouse mAb against mouse testis tissue lysate
References

Tissue-specific localization of the ING4 targeting subunit of the HBO1 histone acetyltransferase in the cytoplasm and nucleus of secretory cells., PMID:40402282

Analysis of patients with colorectal cancer shows a specific increase in serum anti-ING1 autoantibody levels., PMID:37072777

ING3 protein expression profiling in normal human tissues suggest its role in cellular growth and self-renewal., PMID:25819753

Domain recognition of the ING1 tumor suppressor by a panel of monoclonal antibodies., PMID:21707358

Side-by-side analysis of five clinically tested anti-EpCAM monoclonal antibodies., PMID:21044305

Letter to the editor: efficacy and safety of anti-Trop antibodies, R. Cubas, M. Li, C. Chen and Q. Yao, Biochim Biophys Acta 1796 (2009) 309-1., PMID:20079406

Nuclear exclusion of p33ING1b tumor suppressor protein: explored in HCC cells using a new highly specific antibody., PMID:19132896

The predictive value of p53 and p33(ING1b) in patients with Dukes'C colorectal cancer., PMID:17949449

Pharmacokinetic and safety study of subcutaneously administered weekly ING-1, a human engineere monoclonal antibody targeting human EpCAM, in patients with advanced solid tumors., PMID:17693421

Subcellular targeting of p33ING1b by phosphorylation-dependent 14-3-3 binding regulates p21WAF1 expression., PMID:16581770

The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumor suppressor product p33ING1b., PMID:16288740

ING-1, a monoclonal antibody targeting Ep-CAM in patients with advanced adenocarcinomas., PMID:15569986

Generation of a polyclonal antibody specifically against the p33(ING1b) tumor suppressor., PMID:15038618

Technology evaluation: ING-1, XOMA., PMID:14513688

In vitro and in vivo pharmacology and pharmacokinetics of a human engineered monoclonal antibody to epithelial cell adhesion molecule., PMID:12659687

Comparative assessment expression of the inhibitor of growth 1 gene (ING1) in normal and neoplastic tissues., PMID:11991811

Expression of novel ING variants is regulated by thyroid hormone in the Xenopus laevis tadpole., PMID:11600495

UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences., PMID:11353074

A panel of CAb antibodies recognize endogenous and ectopically expressed ING1 protein., PMID:10868796

Antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1: in vitro and in vivo studies with prodrugs of methotrexate and the thymidylate synthase inhibitors GW1031 and GW1843., PMID:9893962

Specific monoclonal antibody raised against the p33ING1 tumor suppressor., PMID:9455706

Toward antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1 and novel in vivo stable prodrugs of methotrexate., PMID:9188478

Influence of estradiol and tamoxifen on susceptibility of human breast cancer cell lines to lysis by lymphokine-activated killer cells., PMID:1734946

Chimeric mouse-human anti-carcinoma antibodies that mediate different anti-tumor cell biological activities., PMID:1873500

Augmentation of antibody dependent cell mediated cytotoxicity following in vivo therapy with recombinant interleukin 2., PMID:2386933

Binding and functional properties of a mouse-human chimeric monoclonal antibody of the human IgG1 subclass with specificity for human carcinomas., PMID:2103354

Datasheet

Document Download

Anti-ING1 Antibody (R4A34).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-ING1 Antibody (R4A34) [RHN79503]
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