Catalog No.
RHN79504
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200
Target
ING1, Inhibitor of growth protein 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UK53
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4A33
Tissue-specific localization of the ING4 targeting subunit of the HBO1 histone acetyltransferase in the cytoplasm and nucleus of secretory cells., PMID:40402282
Analysis of patients with colorectal cancer shows a specific increase in serum anti-ING1 autoantibody levels., PMID:37072777
ING3 protein expression profiling in normal human tissues suggest its role in cellular growth and self-renewal., PMID:25819753
Domain recognition of the ING1 tumor suppressor by a panel of monoclonal antibodies., PMID:21707358
Side-by-side analysis of five clinically tested anti-EpCAM monoclonal antibodies., PMID:21044305
Letter to the editor: efficacy and safety of anti-Trop antibodies, R. Cubas, M. Li, C. Chen and Q. Yao, Biochim Biophys Acta 1796 (2009) 309-1., PMID:20079406
Nuclear exclusion of p33ING1b tumor suppressor protein: explored in HCC cells using a new highly specific antibody., PMID:19132896
The predictive value of p53 and p33(ING1b) in patients with Dukes'C colorectal cancer., PMID:17949449
Pharmacokinetic and safety study of subcutaneously administered weekly ING-1, a human engineere monoclonal antibody targeting human EpCAM, in patients with advanced solid tumors., PMID:17693421
Subcellular targeting of p33ING1b by phosphorylation-dependent 14-3-3 binding regulates p21WAF1 expression., PMID:16581770
The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumor suppressor product p33ING1b., PMID:16288740
ING-1, a monoclonal antibody targeting Ep-CAM in patients with advanced adenocarcinomas., PMID:15569986
Generation of a polyclonal antibody specifically against the p33(ING1b) tumor suppressor., PMID:15038618
Technology evaluation: ING-1, XOMA., PMID:14513688
In vitro and in vivo pharmacology and pharmacokinetics of a human engineered monoclonal antibody to epithelial cell adhesion molecule., PMID:12659687
Comparative assessment expression of the inhibitor of growth 1 gene (ING1) in normal and neoplastic tissues., PMID:11991811
Expression of novel ING variants is regulated by thyroid hormone in the Xenopus laevis tadpole., PMID:11600495
UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences., PMID:11353074
A panel of CAb antibodies recognize endogenous and ectopically expressed ING1 protein., PMID:10868796
Antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1: in vitro and in vivo studies with prodrugs of methotrexate and the thymidylate synthase inhibitors GW1031 and GW1843., PMID:9893962
Specific monoclonal antibody raised against the p33ING1 tumor suppressor., PMID:9455706
Toward antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1 and novel in vivo stable prodrugs of methotrexate., PMID:9188478
Influence of estradiol and tamoxifen on susceptibility of human breast cancer cell lines to lysis by lymphokine-activated killer cells., PMID:1734946
Chimeric mouse-human anti-carcinoma antibodies that mediate different anti-tumor cell biological activities., PMID:1873500
Augmentation of antibody dependent cell mediated cytotoxicity following in vivo therapy with recombinant interleukin 2., PMID:2386933
Binding and functional properties of a mouse-human chimeric monoclonal antibody of the human IgG1 subclass with specificity for human carcinomas., PMID:2103354