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Anti-WAPL Antibody (R4A31)

Catalog #:   RHN74502 Specific References (14) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC
Accession: Q7Z5K2
Overview

Catalog No.

RHN74502

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:20-1:100

Target

Friend of EBNA2 protein, Wings apart-like protein homolog, FOE, KIAA0261, WAPAL, WAPL, WAPL cohesin release factor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q7Z5K2

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4A31

Data Image
  • Immunohistochemical
    IHC-P analysis of testis tissue by WAPL antibody (RHN74502). IHC-P was performed using sections of the formalin-fixed paraffin-embedded testis tissue;Result: Cells in seminiferous ducts are positively stained at the nuclei.
References

Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development., PMID:39179932

Contribution of the IGCR1 regulatory element and the 3'Igh CTCF-binding elements to regulation of Igh V(D)J recombination., PMID:37339228

Contribution of the IGCR1 regulatory element and the 3 'Igh CBEs to Regulation of Igh V(D)J Recombination., PMID:37163018

Igh and Igk loci use different folding principles for V gene recombination due to distinct chromosomal architectures of pro-B and pre-B cells., PMID:37085514

Visualizing looping of two endogenous genomic loci using synthetic zinc-finger proteins with anti-FLAG and anti-HA frankenbodies in living cells., PMID:34465007

Dynamic 3D Locus Organization and Its Drivers Underpin Immunoglobulin Recombination., PMID:33679727

Loop extrusion mediates physiological Igh locus contraction for RAG scanning., PMID:33442057

How DNA loop extrusion mediated by cohesin enables V(D)J recombination., PMID:33422934

Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion., PMID:32612238

The inhibitory effect of a new scFv/tP protein as siRNA delivery system to target hWAPL in cervical carcinoma., PMID:24567178

Wapl localization on the synaptonemal complex, a meiosis-specific proteinaceous structure that binds homologous chromosomes, in the female mouse., PMID:18199270

The complete removal of cohesin from chromosome arms depends on separase., PMID:18003702

Immunization of mice with plasmids coexpressing HPV16 E5 and the novel oncogene hWAPL., PMID:17645509

[Prokaryotic expression and immunogenicity of hWAPL, a norel oncogene related to cervical cancer]., PMID:17553356

Datasheet

Document Download

Anti-WAPL Antibody (R4A31).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-WAPL Antibody (R4A31) [RHN74502]
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