Anti-Human Lambda Light Chain Antibody (R4A18)

Catalog No.

RHN51901

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:500

Target

Ig lambda-1 chain C region, Ig lambda chain C region MGC, IGLC1, Immunoglobulin lambda constant 1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P0CG04

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4A18

Germline polymorphism in the immunoglobulin kappa and lambda loci explain variation in the expressed light chain antibody repertoire., PMID:40501977

Human genetic variation shapes the antibody repertoire across B cell development., PMID:40475565

Comparison of middle molecule removal with expanded hemodialysis versus haemodiafiltration among Chinese hemodialysis patients., PMID:40441692

Crystal-Storing Histiocytosis of the Duodenum in a Patient With IgG-Lambda Multiple Myeloma., PMID:40440188

B cell receptor silencing reveals origin and dependencies of high-grade B cell lymphomas with MYC and BCL2 rearrangements., PMID:40402557

Increasing the developability of lambda chain antibodies: engineering to confer protein L binding activity and its consequences., PMID:40368210

Using bispecific antibodies in a patient with peritoneal dialysis for relapsed multiple myeloma., PMID:40356496

[Application of next-generation sequencing technology for the investigation of immunoglobulin variable region characteristics and their prognostic significance in patients with chronic lymphocytic leukemia]., PMID:40355356

Heterohybridomas producing human immunoglobulin light chains using CD138-selected bone marrow cells., PMID:40330075

[Localized AL amyloidosis]., PMID:40327620

Proliferative glomerulonephritis with monoclonal immunoglobulin deposition coexisting with ANCA-associated glomerulonephritis: a case report., PMID:40308572

Investigating Local Sequence-Structural Attributes of Amyloidogenic Light Chain Variable Domains., PMID:40034034

A case of IgG-type heavy chain amyloidosis with membranous nephropathy-like changes with long-term survival., PMID:40021557

Prevalence and Spectrum of Neuropathies in a Cohort of 585 Patients With Immunoglobulin A Monoclonal Gammopathy., PMID:39968567

[Construction and identification of a sizeable naive human Fab phage display antibody library]., PMID:39965836

[Assessment of serum free light chains in patients with systemic lupus erythematosus]., PMID:39960251

Extramedullary plasmacytoma with the uvula as first affected site: A case report., PMID:39867735

Biomarkers of Intrathecal Synthesis May Be Associated with Cognitive Impairment at MS Diagnosis., PMID:39859538

Comprehensive analysis of gene expressions in ileal mucosa of chickens fed paddy rice and their IgA response to oral vaccination., PMID:39848208

Diagnostic d'un myélome multiple à immunoglobuline D Lambda avec une atteinte rénale sévère 10 ans après un plasmocytome solitaire : Un cas clinique et revue de la littérature., PMID:39812210

Mice carrying the full-length human immunoglobulin loci produce antigen-specific human antibodies with the lambda light chain., PMID:39758990

50 Years of Antibody Numbering Schemes: A Statistical and Structural Evaluation Reveals Key Differences and Limitations., PMID:39727482

EXPRESSION OF IMMUNOGLOBULIN LIGHT CHAIN GENES IN STEREOTYPED CASES FROM UKRAINIAN COHORT OF CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS., PMID:39704461

[IgA vasculitis with necrosis of the small intestine secondary to monoclonal gammopathy of renal significance: A case report]., PMID:39690777

Single-cell analysis of a bi-clonal chronic lymphocytic leukemia reveals two clones with distinct gene expression pattern., PMID:39689719

An updated AL-base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis., PMID:39641756

Discovery of Potent and Selective Pyridone-Based Small Molecule Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains., PMID:39626211

Correlation analysis of laboratory indicators, genetic abnormalities and staging in patients with newly diagnosed multiple myeloma., PMID:39612380

Predicting Structural Consequences of Antibody Light Chain N-Glycosylation in AL Amyloidosis., PMID:39598451

Hybrid Mass Spectrometry Applied across the Production of Antibody Biotherapeutics., PMID:39573914

Serum free light chains in a racially diverse population including African Americans and populations from South Africa., PMID:39571144

[Free Immunoglobulin Light Chains in Patients With Myocarditis: a New Biomarker of Inflammation and Heart Failure]., PMID:39526514

Serum levels of free light chains and syndecan-1 in patients with rheumatoid arthritis and systemic lupus erythematosus., PMID:39509329

Monoclonal Gammopathy in Patients with Neuropathy., PMID:39506578

IgA monoclonal gammopathies are accompanied by higher total TGF-β1 levels than IgG or IgM monoclonal gammopathies., PMID:39506190

A clinical case of B-cell lymphoma in a Japanese Black cow with monoclonal proliferation of B-cells as revealed by polymerase chain reaction based on the immunoglobulin light chain gene., PMID:39496453

Warning values of serum total kappa/lambda ratio for M-proteinemia., PMID:39478462

Clonality Determination by Detecting Unmodified Monoclonal Serum Free Light Chains Using On-Probe Extraction Coupled with Liquid Chromatography-High-Resolution Mass Spectrometry., PMID:39378225

Lambda light chain - restricted non - crystalline proximal tubulopathy with cast nephropathy in multiple myeloma: a case report and literature review., PMID:39350086

An updated AL-Base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis., PMID:39314448

Expression and diagnostic value of serum free light chain in lung cancer., PMID:39311787

Biochemical profile of renal amyloidosis in a Latin American cohort., PMID:39225979

Optimizing the method for expressing human monoclonal antibodies from a single peripheral blood cell from vaccinated donors., PMID:39214236

Features that characterize monoclonal light chain ("myeloma") cast nephropathy with immunofluorescence challenges and emphasis on electron microscopy., PMID:39166773

Failure of Serum Immunofixation Electrophoresis to Detect Intact Monoclonal IgD Lambda Unraveled by Mass Spectrometry., PMID:39162305

Detecting M-Protein via Mass Spectrometry and Affinity Beads: Enrichment With Mixed Kappa-Lambda Beads Enables Prompt Application in Clinical Laboratories., PMID:39161319

Generation of Chicken Antibody Libraries and Selection of Antigen Binders., PMID:39151941

Generation of a Phage Display Chicken Single-Chain Variable Fragment Library., PMID:39151940

Chicken Immunization followed by RNA Extraction and cDNA Synthesis for Antibody Library Preparation., PMID:39151937

Promising response of proliferative glomerulonephritis with monoclonal IgG deposits to low-dose daratumumab: a case report., PMID:39114824

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