Anti-DNMT3L Antibody (R3Z99)

Catalog No.

RHN22204

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400

Target

DNA (cytosine-5)-methyltransferase 3-like, DNMT3L

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9UJW3

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3Z99

Epigenetics and prostate cancer: defining the timing of DNA methyltransferase deregulation during prostate cancer progression., PMID:31864524

The zinc-finger protein basonuclin 2 is required for proper mitotic arrest, prevention of premature meiotic initiation and meiotic progression in mouse male germ cells., PMID:25344072

DNMT3L is a novel marker and is essential for the growth of human embryonal carcinoma., PMID:20460473

Deregulation of DNA methyltransferases and loss of parental methylation at the insulin-like growth factor II (Igf2)/H19 loci in p53 knockout mice prior to tumor development., PMID:15543560

Imprinting regulator DNMT3L is a transcriptional repressor associated with histone deacetylase activity., PMID:12177302

Document Download

Anti-DNMT3L Antibody (R3Z99).pdf