Catalog No.
RHK42702
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
Nuclear zinc finger protein Np95, RING-type E3 ubiquitin transferase UHRF1, RING finger protein 106, Transcription factor ICBP90, E3 ubiquitin-protein ligase UHRF1, Ubiquitin-like PHD and RING finger domain-containing protein 1, NP95, HuNp95, Nuclear protein 95, RNF106, ICBP90, hNp95, UHRF1, Inverted CCAAT box-binding protein of 90 kDa, hUHRF1, Ubiquitin-like-containing PHD and RING finger domains protein 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q96T88
Applications
ELISA, FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3Y94
Potentiating anti-tumor immunity by re-engaging immune synapse molecules., PMID:39999838
Regulation of UHRF1 acetylation by TIP60 is important for colon cancer cell proliferation., PMID:35951156
Crosstalk between macrophage-derived PGE2 and tumor UHRF1 drives hepatocellular carcinoma progression., PMID:35664070
ICBP90 Regulates MIF Expression, Glucocorticoid Sensitivity, and Apoptosis at the MIF Immune Susceptibility Locus., PMID:33844457
PARP inhibitor veliparib and HDAC inhibitor SAHA synergistically co-target the UHRF1/BRCA1 DNA damage repair complex in prostate cancer cells., PMID:30012171
Uhrf1 regulates germinal center B cell expansion and affinity maturation to control viral infection., PMID:29618490
UHRF1 is an Independent Prognostic Factor and a Potential Therapeutic Target of Esophageal Squamous Cell Carcinoma., PMID:29187878
In vitro hydroquinone-induced instauration of histone bivalent mark on human retroelements (LINE-1) in HL60 cells., PMID:27979589
E2F8 as a Novel Therapeutic Target for Lung Cancer., PMID:26089541
A modular open platform for systematic functional studies under physiological conditions., PMID:26007658
CD47 activation-induced UHRF1 over-expression is associated with silencing of tumor suppressor gene p16INK4A in glioblastoma cells., PMID:25550546
Epigenetic dysregulation in salivary glands from patients with primary Sjögren's syndrome may be ascribed to infiltrating B cells., PMID:23478041
Replication-coupled passive DNA demethylation for the erasure of genome imprints in mice., PMID:23241950
M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability., PMID:22411829
UHRF1 phosphorylation by cyclin A2/cyclin-dependent kinase 2 is required for zebrafish embryogenesis., PMID:22072796
Proteomic analysis of chronic pancreatitis and pancreatic adenocarcinoma., PMID:16285947
Cell cycle and/or proliferation markers: what is the best method to discriminate cervical high-grade lesions?, PMID:16226110
Cloning and mapping of Np95 gene which encodes a novel nuclear protein associated with cell proliferation., PMID:9880673
For research use only. Not for human or drug use.
