Catalog No.
RHK37402
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000
Target
IRF, RNF28, Iris RING finger protein, SMRZ, MURF1, MuRF-1, MuRF1, Striated muscle RING zinc finger protein, Tripartite motif-containing protein 63, TRIM63, E3 ubiquitin-protein ligase TRIM63, Muscle-specific RING finger protein 1, RING finger protein 28, RING-type E3 ubiquitin transferase TRIM63
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q969Q1
Applications
ELISA, FCM, IF, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3Y79
11-beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) gene expression in muscle is linked to reduced skeletal muscle index in sarcopenic patients., PMID:37943405
RANKL Mediates Muscle Atrophy and Dysfunction in a Cigarette Smoke-induced Model of Chronic Obstructive Pulmonary Disease., PMID:33689672
Emerging Strategies Targeting Catabolic Muscle Stress Relief., PMID:32630118
Adipocytes suppress differentiation of muscle cells in a co-culture system., PMID:30585366
Primary and Metastatic Melanoma With NTRK Fusions., PMID:29683819
Pathogenic role of anti-signal recognition protein and anti-3-Hydroxy-3-methylglutaryl-CoA reductase antibodies in necrotizing myopathies: Myofiber atrophy and impairment of muscle regeneration in necrotizing autoimmune myopathies., PMID:28224701
[Translocation of MuRF isoforms to nuclei in postural muscle during gravitational unloading]., PMID:25868327
Inhibition of activin A ameliorates skeletal muscle injury and rescues contractile properties by inducing efficient remodeling in female mice., PMID:24655377
Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptors., PMID:24220501
Muscle-specific regulation of the mTOR signaling pathway in MuSK antibody seropositive (MuSK+) experimental autoimmune Myasthenia gravis (EAMG)., PMID:23933211
Construction, expression and characterization of a single chain variable fragment antibody against human myostatin., PMID:23919379
Developmental regulation of MURF E3 ubiquitin ligases in skeletal muscle., PMID:22426552
Joint inflammation alters gene and protein expression and leads to atrophy in the tibialis anterior muscle in rats., PMID:21959222
Epigallocatechin-3-gallate effectively attenuates skeletal muscle atrophy caused by cancer cachexia., PMID:21397390
High-mobility group box 1 release and redox regulation accompany regeneration and remodeling of skeletal muscle., PMID:21294652
MuSK antibody positive myasthenia gravis plasma modifies MURF-1 expression in C2C12 cultures and mouse muscle in vivo., PMID:16213598
Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I., PMID:15601779
Muscle-specific RING finger-2 (MURF-2) is important for microtubule, intermediate filament and sarcomeric M-line maintenance in striated muscle development., PMID:15199100