Anti-LIN28A Antibody (R3Y77)

Catalog No.

RHK37001

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IF: 1:200-1:1000, WB: 1:500-1:2000

Target

CSDD1, Zinc finger CCHC domain-containing protein 1, LIN28, LIN28A, Lin-28A, Protein lin-28 homolog A, ZCCHC1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9H9Z2

Applications

IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3Y77

Lin28a forms an RNA-binding complex with Igf2bp3 to regulate m6A-modified stress response genes in stress granules of muscle stem cells., PMID:39021312

Prostate cancer research: tools, cell types, and molecular targets., PMID:38595814

Brain and Spinal Cord Tumors of Embryonic Origin., PMID:37452947

Embryonal tumors with multilayered rosettes, C19MC-altered or not elsewhere classified: Clinicopathological characteristics, prognostic factors, and outcomes of 17 children from 2018 to 2022., PMID:36353532

[Embryonal tumor with multilayered rosettes (ETMR): case report and literature review]., PMID:35758080

Let-7, Lin28 and Hmga2 Expression in Ciliary Epithelium and Retinal Progenitor Cells., PMID:33749722

Usefulness of PAX8 Immunohistochemistry in Adult Intraocular Tumor Diagnosis., PMID:33002562

A nanobody targeting the LIN28:let-7 interaction fragment of TUT4 blocks uridylation of let-7., PMID:32060122

MicroRNA Let-7 in B lymphocyte activation., PMID:31085798

Critical role of Lin28-TNFR2 signalling in cardiac stem cell activation and differentiation., PMID:30734494

Let-7 Suppresses B Cell Activation through Restricting the Availability of Necessary Nutrients., PMID:29337138

JAK2V617F influences epigenomic changes in myeloproliferative neoplasms., PMID:29066347

Replacing reprogramming factors with antibodies selected from combinatorial antibody libraries., PMID:28892074

Sox2 regulates Müller glia reprogramming and proliferation in the regenerating zebrafish retina via Lin28 and Ascl1a., PMID:28577895

Intraocular Medulloepitheliomas and Embryonal Tumors With Multilayered Rosettes of the Brain: Comparative Roles of LIN28A and C19MC., PMID:25748578

Directed cardiomyogenesis of autologous human induced pluripotent stem cells recruited to infarcted myocardium with bioengineered antibodies., PMID:25132967

Reversible acetylation of Lin28 mediated by PCAF and SIRT1., PMID:24631505

[In vitro tumorigenicity tests for process control of health care products derived from human induced pluripotent stem cells]., PMID:24292187

TNF, acting through inducibly expressed TNFR2, drives activation and cell cycle entry of c-Kit+ cardiac stem cells in ischemic heart disease., PMID:23712715

A signature for induced pluripotent stem cell-associated genes in colorectal cancer., PMID:23307247

Systematic screens of proteins binding to synthetic microRNA precursors., PMID:23221640

LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR)., PMID:23161096

Highly sensitive in vitro methods for detection of residual undifferentiated cells in retinal pigment epithelial cells derived from human iPS cells., PMID:22615985

Induction of the RNA regulator LIN28A is required for the growth and pathogenesis of RESTless breast tumors., PMID:22532168

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