Catalog No.
RHJ91403
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000
Target
Dnmt3a, DNA MTase HsaIIIA, DNMT3A, M.HsaIIIA, DNA (cytosine-5)-methyltransferase 3A, DNA methyltransferase HsaIIIA
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y6K1
Applications
ELISA, FCM, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3X83
Biological and Clinical Relevance of Genetic Alterations in Peripheral T-cell Lymphomas., PMID:40416001
Combined Effect of Conventional Chemotherapy with Epigenetic Modulators on Glioblastoma., PMID:40004468
DNMT3A transcriptionally downregulated by KLF5 alleviates LPS-induced inflammatory response and promotes osteogenic differentiation in hPDLSCs., PMID:39476105
Clonal hematopoiesis and atherosclerosis., PMID:39352379
Long-term longitudinal analysis of 4,187 participants reveals insights into determinants of clonal hematopoiesis., PMID:39251642
A combination of 5-azacytidine and nivolumab is a potentially effective rescue therapy in relapsed/refractory AITL., PMID:38983865
Effect of Clonal Hematopoiesis Mutations and Canakinumab Treatment on Incidence of Solid Tumors in the CANTOS Randomized Clinical Trial., PMID:38701435
Germline and Somatic Mutations in DNA Methyltransferase 3A (DNMT3A) Predispose to Pulmonary Arterial Hypertension (PAH) in Humans and Mice: Implications for Associated PAH., PMID:38234783
Clonal haematopoiesis across the age spectrum of vasculitis patients with Takayasu's arteritis, ANCA-associated vasculitis and giant cell arteritis., PMID:38049983
Amino acids analysis reveals serum methionine contributes to diagnosis of the Kawasaki disease in mice and children., PMID:38008045
Philadelphia chromosome-negative myeloproliferative chronic neoplasms: is clonal hematopoiesis the main determinant of autoimmune and cardio-vascular manifestations?, PMID:37915324
Secondary Pure Red Cell Aplasia During Daratumumab/ Hyaluronidase Therapy for Multiple Myeloma., PMID:37877806
Composite B-cell and T-cell lymphomas: clinical, pathological, and molecular features of three cases and literature review., PMID:37551557
Genetic modification of inflammation- and clonal hematopoiesis-associated cardiovascular risk., PMID:37498674
Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis., PMID:37045808
Pathologic and molecular insights in nodal T-follicular helper cell lymphomas., PMID:36793612
Novel Molecular Therapies and Genetic Landscape in Selected Rare Diseases with Hematologic Manifestations: A Review of the Literature., PMID:36766791
Electrostatic anti-CD33-antibody-protamine nanocarriers as platform for a targeted treatment of acute myeloid leukemia., PMID:36457063
Autoantibody against Tumor-Associated Antigens as Diagnostic Biomarkers in Hispanic Patients with Hepatocellular Carcinoma., PMID:36291095
Helicobacter pylori infection and DNMT3a polymorphism are associated with the presence of premature coronary artery disease and subclinical atherosclerosis. Data from the GEA Mexican Study., PMID:35961487
Cardiovascular Disease in Myeloproliferative Neoplasms: JACC: CardioOncology State-of-the-Art Review., PMID:35818539
TET2-Driven Clonal Hematopoiesis and Response to Canakinumab: An Exploratory Analysis of the CANTOS Randomized Clinical Trial., PMID:35385050
[Mechanism of Mycobacterium tuberculosis on interleukin-6 receptor 3'-untranslated region methylation in CD4+T cells]., PMID:35381636
Pseudo-mutant P53 is a unique phenotype of DNMT3A-mutated pre-leukemia., PMID:35199506
Clonal haematopoiesis of indeterminate potential and cardiovascular events in systemic lupus erythematosus (HEMATOPLUS study)., PMID:35176141
Global DNA methylation and increased DNMT3A expression in multiple myeloma patients., PMID:35173353
Clonal hematopoiesis is associated with increased risk of progression of asymptomatic Waldenström macroglobulinemia., PMID:34847227
Donor Clonal Hematopoiesis and Recipient Outcomes After Transplantation., PMID:34793200
Embryo culture media differentially alter DNA methylating enzymes and global DNA methylation in embryos and oocytes., PMID:34741214
Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis., PMID:34698806
Interruption of neutrophil extracellular traps formation dictates host defense and tubular HOXA5 stability to augment efficacy of anti-Fn14 therapy against septic AKI., PMID:34646379
Personalized Single-Cell Proteogenomics to Distinguish Acute Myeloid Leukemia from Non-Malignant Clonal Hematopoiesis., PMID:34258102
MALAT1 Promotes Tumorigenesis and Increases Cellular Sensitivity to Herceptin in HER2-positive Breast Cancer., PMID:34148540
Bisulphite miRNA-seq reveals widespread CpG and non-CpG 5-(hydroxy)methyl-Cytosine in human microRNAs., PMID:33980133
Molecular classification and prognosis in younger adults with acute myeloid leukemia and intermediate-risk cytogenetics treated or not by gemtuzumab ozogamycin: Final results of the GOELAMS/FILO acute myeloid leukemia 2006-intermediate-risk trial., PMID:33765335
Angioimmunoblastic T-Cell Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Novel Form of Composite Lymphoma Potentially Mimicking Richter Syndrome., PMID:33739791
Integrative analysis of a phase 2 trial combining lenalidomide with CHOP in angioimmunoblastic T-cell lymphoma., PMID:33496747
Nanobody-mediated control of gene expression and epigenetic memory., PMID:33483487
Effect of DNMT3A polymorphisms on CpG island hypermethylation in gastric mucosa., PMID:33066747
CREB Participates in Paclitaxel-Induced Neuropathic Pain Genesis Through Transcriptional Activation of Dnmt3a in Primary Sensory Neurons., PMID:33051852
Investigation of GSTP1 and epigenetic regulators expression pattern in a population of Iranian patients with prostate cancer., PMID:32831196
Clonal haematopoiesis is increased in early onset in systemic sclerosis., PMID:32757002
Melatonin-induced suppression of DNA methylation promotes odontogenic differentiation in human dental pulp cells., PMID:32718272
Battle of the clones: paroxysmal nocturnal hemoglobinuria vs myelodysplastic syndrome., PMID:32533252
Cytosine methylation of mature microRNAs inhibits their functions and is associated with poor prognosis in glioblastoma multiforme., PMID:32098627
Association analysis of DNA methyltransferases in IgA nephropathy., PMID:31931367
Epigenetics and prostate cancer: defining the timing of DNA methyltransferase deregulation during prostate cancer progression., PMID:31864524
[Current standard in diagnostic and therapy of peripheral T-cell lymphoma]., PMID:31594013
Regulation of DNA methylation levels in the process of oral mucosal regeneration in a rat oral ulcer model., PMID:31286466
Decreased DNA methyltransferases expression is associated with coronary artery lesion formation in Kawasaki disease., PMID:31171909
For research use only. Not for human or drug use.
