Catalog No.
RHJ90302
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000
Target
IRAK-3, Interleukin-1 receptor-associated kinase 3, IRAK3, IRAK-M, IL-1 receptor-associated kinase M
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y616
Applications
ELISA, FCM, IF, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3X76
Genetic Factors of Predisposition and Clinical Characteristics of Rheumatoid Arthritis in Russian Patients., PMID:34070522
Identification of Potential Core Genes in Immunoglobulin-Resistant Kawasaki Disease Using Bioinformatics Analysis., PMID:32421987
Disturbed Transcription of TLRs' Negative Regulators and Cytokines Secretion among TLR4- and 9-Activated PBMCs of Agammaglobulinemic Patients., PMID:31185757
The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation., PMID:29686383
IRAK2 is associated with susceptibility to rheumatoid arthritis., PMID:29129009
Tolerance and Cross-Tolerance following Toll-Like Receptor (TLR)-4 and -9 Activation Are Mediated by IRAK-M and Modulated by IL-7 in Murine Splenocytes., PMID:26218271
Gastric LTi cells promote lymphoid follicle formation but are limited by IRAK-M and do not alter microbial growth., PMID:25603827
Blood mRNA expression profiling predicts survival in patients treated with tremelimumab., PMID:24721645
IRAK-M deficiency promotes the development of type 1 diabetes in NOD mice., PMID:24696448
Association of self-DNA mediated TLR9-related gene, DNA methyltransferase, and cytokeratin protein expression alterations in HT29-cells to DNA fragment length and methylation status., PMID:24459426
Macrophage phenotype controls long-term AKI outcomes--kidney regeneration versus atrophy., PMID:24309188
Endogenous HMGB1 is required in endotoxin tolerance., PMID:23866790
Involvement of IRAKs and TRAFs in anti-β₂GPI/β₂GPI-induced tissue factor expression in THP-1 cells., PMID:21901230
Interleukin-1 receptor-associated kinase-M suppresses systemic lupus erythematosus., PMID:21875872
Role of IL-1 receptor-associated kinase-M (IRAK-M) in priming of immune and inflammatory responses by nitrogen bisphosphonates., PMID:21690387
Analysis of immunostimulatory activity of Porphyromonas gingivalis fimbriae conferred by Toll-like receptor 2., PMID:20558141
Critical role of IL-1 receptor-associated kinase-M in regulating chemokine-dependent deleterious inflammation in murine influenza pneumonia., PMID:20042589
Association of interacting genes in the toll-like receptor signaling pathway and the antibody response to pertussis vaccination., PMID:18987746
Inflammatory responses associated with acute coronary syndrome up-regulate IRAK-M and induce endotoxin tolerance in circulating monocytes., PMID:17621545
Toll-like receptor 2 ligand mediates the upregulation of angiogenic factor, vascular endothelial growth factor and interleukin-8/CXCL8 in human rheumatoid synovial fibroblasts., PMID:17182109
Tumor cells deactivate human monocytes by up-regulating IL-1 receptor associated kinase-M expression via CD44 and TLR4., PMID:15728517
Nitric oxide activates the expression of IRAK-M via the release of TNF-alpha in human monocytes., PMID:15275867
For research use only. Not for human or drug use.
