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Anti-CCL26/Eotaxin-3/TSC-1 Antibody (R3X61)

Catalog #:   RHJ84801 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: WB
Accession: Q9Y258
Overview

Catalog No.

RHJ84801

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

WB: 1:500-1:1000

Target

CC chemokine IMAC, C-C motif chemokine 26, CCL26, Small-inducible cytokine A26, Macrophage inflammatory protein 4-alpha, Thymic stroma chemokine-1, TSC-1, MIP-4-alpha, Eotaxin-3, SCYA26

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9Y258

Applications

WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3X61

Data Image
  • Western blot
    Result: RHJ84801 can detect human CCL26 by Western blotting.
References

Inhibition of IL-4Rα reduces CCL26 in bronchial epithelial cells from COPD patients., PMID:40470156

T2 cytokine-driven alarmin and antiviral responses in asthma: insights into immune modulation and the role of IL-4Rα targeting., PMID:40370530

Blocking of IL-4/IL-13 Signalling With Dupilumab Results in Restoration of Serum and Cutaneous Abnormalities in Netherton Syndrome., PMID:40344324

Leptin augments IL-13-induced airway eotaxins and submucosal eosinophilia in obesity-associated asthma., PMID:39581293

Non-invasive strategy: Developing a topical IL-4Rα-specific nanobody for the treatment of allergic airway diseases., PMID:39108557

Airway proteomics reveals broad residual anti-inflammatory effects of prednisolone in mepolizumab-treated asthma., PMID:39097197

Effect of benralizumab on histopathology and inflammatory signatures in a clinical cohort of eosinophilic esophagitis., PMID:38986036

Nicotiana benthamiana-derived dupilumab-scFv reaches deep into the cultured human nasal epithelial cells and inhibits CCL26 expression., PMID:38914666

Expression of inducible nitric oxide synthase, nitrotyrosine, eosinophilic peroxidase, eotaxin-3, and galectin-3 in patients with gastroesophageal reflux disease, eosinophilic esophagitis, and in healthy controls: a semiquantitative image analysis of 3,3'-diaminobenzidine-stained esophageal biopsies., PMID:38679488

Dupilumab-associated head and neck dermatitis shows a pronounced type 22 immune signature mediated by oligoclonally expanded T cells., PMID:38565563

Targeting IL-13 with tralokinumab normalizes type 2 inflammation in atopic dermatitis both early and at 2 years., PMID:38563683

The functional role of CST1 and CCL26 in asthma development., PMID:38270326

Th2 cytokine signaling through IL-4Rα increases eotaxin-3 secretion and tension in human esophageal smooth muscle., PMID:37933466

Exploration of efficacy and mechanism of 0.05% cyclosporine eye drops (II) monotherapy in allergic conjunctivitis-associated dry eye., PMID:37904000

Efficacy of dupilumab in patients with uncontrolled, moderate-to-severe asthma with fungal sensitization., PMID:37752621

Eotaxin-2 and eotaxin-3 in malaria exposure and pregnancy., PMID:36380370

Pediatric Eosinophilic Esophagitis: Searching for Serologic Markers., PMID:36197779

Dipeptidyl Peptidase 4 Inhibitor‒Associated Bullous Pemphigoid Is Characterized by an Altered Expression of Cytokines in the Skin., PMID:35921900

Type-2 Cytokines Promote the Secretion of the Eosinophil-Attractant CCL26 by Intestinal Epithelial Cells in Food-Sensitized Patients., PMID:35799778

The Role of Heparan Sulfate in CCL26-Induced Eosinophil Chemotaxis., PMID:35742962

IL-25 blockade augments antiviral immunity during respiratory virus infection., PMID:35508632

Adult allergic rhinitis sufferers have unique nasal mucosal and peripheral blood immune gene expression profiles: A case-control study., PMID:34637606

Analysis of the signal cross talk via CCL26 in the tumor microenvironment in osteosarcoma., PMID:34518591

A Comprehensive Analysis of Immune Constituents in Blood and Bronchoalveolar Lavage Allows Identification of an Immune Signature of Severe Asthma in Children., PMID:34349761

Dupilumab suppresses type 2 inflammatory biomarkers across multiple atopic, allergic diseases., PMID:34037993

Immunoinflammatory Biomarkers in Serum Are Associated with Disease Severity in Atopic Dermatitis., PMID:33730733

Biomarkers in atopic dermatitis-a review on behalf of the International Eczema Council., PMID:33516871

Exploration of biomarkers to predict clinical improvement of atopic dermatitis in patients treated with dupilumab: A study protocol., PMID:32957324

A randomized, placebo-controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodelling in uncontrolled asthma (CLAVIER)., PMID:32909660

CCL26 regulates the proportion of CD4+CD25+FOXP3+ Tregs and the production of inflammatory factors in peripheral blood mononuclear cells following acute ischemic stroke via the STAT5 pathway., PMID:32855707

Increased serum CCL26 level is a potential biomarker for the effectiveness of anti-PD1 antibodies in patients with advanced melanoma., PMID:32658051

Thermal Bioprinting Causes Ample Alterations of Expression of LUCAT1, IL6, CCL26, and NRN1L Genes and Massive Phosphorylation of Critical Oncogenic Drug Resistance Pathways in Breast Cancer Cells., PMID:32154227

IgG4 Related Autoimmune Pancreatitis: An Overview and the Emerging Role of Serum Eotaxin as a Potential Treatment Target., PMID:31542909

Pathogenesis of Atopic Dermatitis: Current Paradigm., PMID:31182684

Comparison of the chemokine profiles in the bronchoalveolar lavage fluid between IgG4-related respiratory disease and sarcoidosis: CC-chemokine ligand 1 might be involved in the pathogenesis of sarcoidosis., PMID:31063909

Serum and blister fluid levels of cytokines and chemokines in pemphigus and bullous pemphigoid., PMID:30844553

Dupilumab in patients with uncontrolled asthma: type 2 biomarkers might be predictors of therapeutic efficacy., PMID:30821528

Human lung tissue provides highly relevant data about efficacy of new anti-asthmatic drugs., PMID:30500834

Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis., PMID:30194992

Mesenchymal stem cells up-regulate the invasive potential of prostate cancer cells via the eotaxin-3/CCR3 axis., PMID:30029937

Flavanol-Rich Cocoa Powder Interacts with Lactobacillus rhamnossus LGG to Alter the Antibody Response to Infection with the Parasitic Nematode Ascaris suum., PMID:29023393

Immunohistochemical differentiation of eosinophilic esophageal myositis from eosinophilic esophagitis., PMID:27262491

Hypoxia induces myeloid-derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C-C motif) ligand 26., PMID:27228567

An Overlook to the Characteristics and Roles Played by Eotaxin Network in the Pathophysiology of Food Allergies: Allergic Asthma and Atopic Dermatitis., PMID:26861136

Comparison of eotaxin-3 biomarker in patients with eosinophilic oesophagitis, proton pump inhibitor-responsive oesophageal eosinophilia and gastro-oesophageal reflux disease., PMID:26011446

Serum biomarkers in patients with relapsing eosinophilic granulomatosis with polyangiitis (Churg-Strauss)., PMID:25812008

Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis., PMID:25482871

IL-27 and type 2 immunity in asthmatic patients: association with severity, CXCL9, and signal transducer and activator of transcription signaling., PMID:25312760

Distinctive cytokine, chemokine, and antibody responses in Echinococcus multilocularis-infected patients with cured, stable, or progressive disease., PMID:24509604

Editorial: are all eotaxins created equal?, PMID:23906965

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-CCL26/Eotaxin-3/TSC-1 Antibody (R3X61) [RHJ84801]
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