Catalog No.
RHJ80803
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000
Target
TMS1, CARD5, Caspase recruitment domain-containing protein 5, Apoptosis-associated speck-like protein containing a CARD, PYD and CARD domain-containing protein, ASC, PYCARD, hASC, Target of methylation-induced silencing 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9ULZ3
Applications
ELISA, FCM, IF, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3X48
Adipose-Derived Mesenchymal Stromal/Stem Cells Reduce Inflammatory Responses and Partially Alleviate Skin Symptoms in Imiquimod-Induced Psoriasis-Like Dermatitis Model Mice., PMID:40500215
Shikonin inhibits NLRP3 inflammasome activation and controls inflammatory disease., PMID:40447675
Isolation and Characterization of Equine Mesenchymal Stromal/Stem Cells., PMID:40445292
Targeted fusion of antibody-secreting cells: Unlocking monoclonal antibody production with hybridoma technology., PMID:40418588
Use of sintilimab in primary adenosquamous carcinoma of the liver results in pathological complete response: a case report and literature review., PMID:40370460
Modulating adipose-derived stromal cells' secretomes by culture conditions: effects on angiogenesis, collagen deposition, and immunomodulation., PMID:40267340
Effectiveness and tolerability of atogepant in the prevention of migraine: A real life, prospective, multicentric study (the STAR study)., PMID:40267275
Macrophage-Hosted Porphyromonas gingivalis Is a Risk Factor for Cataract Development., PMID:40266593
Clinical perspective: Advancing hemophilia treatment through gene therapy approaches., PMID:40263938
Influenza A hemagglutinin virus-like particles confer protection against influenza B virus infection., PMID:40230200
Urine-derived stem cells from patients alleviate lupus nephritis via regulating macrophage polarization in a CXCL14-dependent manner., PMID:40204070
Decoding plasma cell maturation dynamics with BCMA., PMID:40134424
Activated αβ T- and reduced mucosa-associated invariant T cells in LGI1- and CASPR2-encephalitis., PMID:40094812
EZH2 coordinates memory B-cell programming and recall responses., PMID:40073167
Gut IgA-antibody secreting cells segregate into four Blimp1+ subsets based on differential expression of IgA and Ki-67 and are retained following prolonged αCD20 B cell depletion in mice., PMID:40073093
CD21lo B cell subsets are recruited to the central nervous system in acute neuromyelitis optica., PMID:40042820
Profile of Humoral Immunity and B Cell Pool in Infection with the SARS-CoV-2 Prototype Strain and AZD1222 (ChAdOx nCoV-19) Vaccination., PMID:40006648
Deep profiling of B cells responding to various pathogens uncovers compartments in IgG memory B cell and antibody-secreting lineages., PMID:39970201
Antibody responses in Klebsiella pneumoniae bloodstream infection: a prospective cohort study., PMID:39952262
Metformin Ameliorates Ulcerative Colitis Through Inhibiting NLRP3 Inflammasome Activation., PMID:39931167
A Site-Specific MiniAp4-Trastuzumab Conjugate Prevents Brain Metastasis., PMID:39924896
Accurate evaluation of factor VIII activity of efanesoctocog alfa in the presence of emicizumab., PMID:39798924
Cost effectiveness of different treatment strategies with natalizumab for pregnant women with multiple sclerosis., PMID:39776288
Receptor Binding Domain-Specific B Cell Memory Responses Among Individuals Vaccinated Against SARS-CoV-2., PMID:39772064
Immunological memory in a teleost fish: common carp IgM+ B cells differentiate into memory and plasma cells., PMID:39759525
Depletion of Adipose Stroma-Like Cancer-Associated Fibroblasts Potentiates Pancreatic Cancer Immunotherapy., PMID:39620946
Therapeutic effects of extracellular vesicles derived from mesenchymal stem cells primed with disease-conditioned-immune cells in systemic lupus erythematosus., PMID:39558370
Cost-Effectiveness of Trastuzumab Deruxtecan in Patients with Unresectable or Metastatic HER2-Low Breast Cancer Who Have Received Prior Chemotherapy., PMID:39531128
Alleviation of COVID-19 Symptoms and Reduction in Healthcare Utilization Among High-risk Patients Treated With Nirmatrelvir/Ritonavir (NMV/R): A Phase 3 Randomized Trial., PMID:39523543
Concizumab prophylaxis in people with haemophilia A or haemophilia B without inhibitors (explorer8): a prospective, multicentre, open-label, randomised, phase 3a trial., PMID:39521008
Protocol for developing Pseudomonas aeruginosa type III secretion system-neutralizing monoclonal antibodies from human B cells., PMID:39520687
Progressive polyadenylation and m6A modification of Ighg1 mRNA maintain IgG1 antibody homeostasis in antibody-secreting cells., PMID:39476842
Navigating the Landscape of B Cell Mediated Immunity and Antibody Monitoring in SARS-CoV-2 Vaccine Efficacy: Tools, Strategies and Clinical Trial Insights., PMID:39460256
Unravelling Transplant-Ineligible Newly Diagnosed Multiple Myeloma Treatment in Real-World Practice in Spain: The CARINAE Study., PMID:39458913
Clinical significance of blood cell ratios in healthy and sick Leishmania infantum-seropositive dogs., PMID:39444011
[Electroacupuncture preconditioning prevents urticaria by regulating inflammatory response in rats with urticaria]., PMID:39433365
Early divergent modulation of NLRP2's and NLRP3's inflammasome sensors vs. AIM2's one by signals from Aβ·Calcium-sensing receptor complexes in human astrocytes., PMID:39426463
SIV-specific antibodies protect against inflammasome-driven encephalitis in untreated macaques., PMID:39383041
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination., PMID:39333316
A cost-minimization analysis of anti-VEGFs for the treatment of neovascular age-related macular degeneration in the Netherlands., PMID:39322853
SMARCA5-mediated chromatin remodeling is required for germinal center formation., PMID:39297882
Efficacy of galcanezumab in migraine central sensitization., PMID:39294310
Datopotamab-deruxtecan plus durvalumab in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial., PMID:39277672
Datopotamab-deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial., PMID:39277671
Engineering potent chimeric antigen receptor T cells by programming signaling during T-cell activation., PMID:39266656
Function-first discovery of high affinity monoclonal antibodies using Nanovial-based plasma B cell screening., PMID:39229089
High-throughput single-cell screening of viable hybridomas and patient-derived antibody-secreting cells using punchable microwells., PMID:39206935
C-ter100 peptide derived from Vibrio vEP-45 protease acts as a pathogen-associated molecular pattern to induce inflammation and innate immunity., PMID:39186780
Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells., PMID:39143416
For research use only. Not for human or drug use.
