Catalog No.
RHJ80501
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
Heat shock factor protein 4, Heat shock transcription factor 4, HSF4, HSTF 4, HSF 4, hHSF4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9ULV5
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3X46
Genetic mutation in HSF4 is associated with retinal degeneration in mice., PMID:40023307
Development and verification of a combined immune- and cancer-associated fibroblast related prognostic signature for colon adenocarcinoma., PMID:38312843
HSF4 Transcriptionally Activates Autophagy by Regulating ATG9a During Lens Terminal Differentiation., PMID:37266953
Knockout of miR-184 in zebrafish leads to ocular abnormalities by elevating p21 levels., PMID:37086087
Biotin attenuates heat shock factor 4b transcriptional activity by lysine 444 biotinylation., PMID:35198740
Deficiency of heat shock factor 4 promotes lens epithelial cell senescence through upregulating p21cip1 expression., PMID:34339841
Knockout of DNase1l1l abrogates lens denucleation process and causes cataract in zebrafish., PMID:32061775
Heat shock factor 4 regulates lysosome activity by modulating the αB-crystallin-ATP6V1A-mTOR complex in ocular lens., PMID:31786107
Downregulation of heat shock factor 4 transcription activity via MAPKinase phosphorylation at Serine 299., PMID:30316871
A zebrafish model of foxe3 deficiency demonstrates lens and eye defects with dysregulation of key genes involved in cataract formation in humans., PMID:29713869
Heat shock factor 4 regulates the expression of HSP25 and alpha B-crystallin by associating with DEXD/H-box RNA helicase UAP56., PMID:29164525
A novel frameshift mutation in CX46 associated with hereditary dominant cataracts in a Chinese family., PMID:28546921
Heat shock factor 4 regulates lens epithelial cell homeostasis by working with lysosome and anti-apoptosis pathways., PMID:27586257
Developmentally dictated expression of heat shock factors: exclusive expression of HSF4 in the postnatal lens and its specific interaction with alphaB-crystallin heat shock promoter., PMID:15308659
Heat shock factor-4 (HSF-4a) is a repressor of HSF-1 mediated transcription., PMID:11500947
Flow cytometric measurement of p53 protein expression and DNA content in paraffin-embedded tissue from bronchial carcinomas., PMID:1935458
For research use only. Not for human or drug use.
