Catalog No.
RHJ78302
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, IHC: 1:200-1:1000
Target
Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha, LEF-1, TCF1-alpha, LEF1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UJU2
Applications
ELISA, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3X43
Basal cell adenoma with S100 protein-positive "stroma": a distinct triphasic salivary gland neoplasm characterized by CTNNB1 mutation., PMID:40515848
MBD2 promotes B cell differentiation and BCR signaling in systemic lupus erythematosus by regulating the LEF-1-PTEN-PI3K axis., PMID:40467564
Novel Aptamers Targeting Sclerostin Loop3 Improve Skeletal and Muscle Properties Without Adverse Cardiovascular Effects in Orchiectomized Mice., PMID:40464222
Expression of Lymphoid Enhancer-Binding Factor 1 in Cancer-Associated Fibroblasts Mediates Tumor Growth and Transdifferentiation Toward Squamous Cell Carcinoma in Human Breast Cancer., PMID:39887653
Glycoengineering-based anti-PD-1-iRGD peptide conjugate boosts antitumor efficacy through T cell engagement., PMID:38843844
Utility of next-generation sequencing in the diagnosis of metastatic melanoma: A case report., PMID:38757469
LepR-expressing cells are a critical population in periodontal healing post periodontitis., PMID:38630879
Remote Activation of Mechanotransduction via Integrin Alpha-5 via Aptamer-Conjugated Magnetic Nanoparticles Promotes Osteogenesis., PMID:38258032
Efficient delivery of the lncRNA LEF1-AS1 through the antibody LAIR-1 (CD305)-modified Zn-Adenine targets articular inflammation to enhance the treatment of rheumatoid arthritis., PMID:38062469
PD1 is transcriptionally regulated by LEF1 in mature T cells., PMID:37523793
Updated Salivary Gland Immunohistochemistry: A Review., PMID:37074867
Netrin-1 binding to Unc5B regulates Blood-Retina Barrier integrity., PMID:36711611
MTDH antisense oligonucleotides reshape the immunosuppressive tumor microenvironment to sensitize Hepatocellular Carcinoma to immune checkpoint blockade therapy., PMID:35609735
NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria., PMID:35029280
Adiponectin negatively regulates pigmentation, Wnt/β-catenin and HGF/c-Met signalling within human scalp hair follicles ex vivo., PMID:34854998
The combination of hair follicle-specific marker LHX2 and co-expressed marker can distinguish between sweat gland placodes and hair placodes in rat., PMID:34581932
Toxicity of thioacetamide and protective effects of quercetin in zebrafish (Danio rerio) larvae., PMID:34227734
A comparison of the usefulness of nuclear beta-catenin in the diagnosis of desmoid-type fibromatosis among commonly used anti-beta-catenin antibodies., PMID:33788979
Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation., PMID:33493531
TFH cells depend on Tcf1-intrinsic HDAC activity to suppress CTLA4 and guard B-cell help function., PMID:33372138
Cortical bone adaptation to a moderate level of mechanical loading in male Sost deficient mice., PMID:33339872
[Sequential development of mantle cell lymphoma following chronic lymphocytic leukemia]., PMID:32224586
A Stem Cell Reporter for Investigating Pluripotency and Self-Renewal in the Rat., PMID:31902707
Transforming growth factor-β1 enhances proliferative and metastatic potential by up-regulating lymphoid enhancer-binding factor 1/integrin αMβ2 in human renal cell carcinoma., PMID:31848806
Wnt/β-Catenin Pathway-Regulated Fibromodulin Expression Is Crucial for Breast Cancer Metastasis and Inhibited by Aspirin., PMID:31824307
Ectonucleotide pyrophosphatase 2 (ENPP2) plays a crucial role in myogenic differentiation through the regulation by WNT/β-Catenin signaling., PMID:31805399
Primary Low-Grade B-Cell Lymphoma of Skull With Translocation Between Immunoglobulin and Interferon Regulatory Factor 4 Genes., PMID:31631721
The usefulness of lymphoid enhancer-binding factor 1 and androgen receptor in diagnosing solid pseudopapillary neoplasm of the pancreas on cytopathology., PMID:31584754
Myometrial Cells Stimulate Self-Renewal of Endometrial Mesenchymal Stem-Like Cells Through WNT5A/β-Catenin Signaling., PMID:31414525
Immunohistochemistry Innovations for Diagnosis and Tissue-Based Biomarker Detection., PMID:31338668
Canonical Wnt/β-catenin signaling activation in soft-tissue sarcomas: A comparative study of synovial sarcoma and leiomyosarcoma., PMID:30505422
Human Lymph Nodes Maintain TCF-1hi Memory T Cells with High Functional Potential and Clonal Diversity throughout Life., PMID:30111633
FGF23 Regulates Wnt/β-Catenin Signaling-Mediated Osteoarthritis in Mice Overexpressing High-Molecular-Weight FGF2., PMID:29718273
Anti-CXCL4 monoclonal antibody accelerates telogen to anagen transition and attenuates apoptosis of the hair follicle in mice., PMID:28810552
Diagnostic Utility of Lymphoid Enhancer Binding Factor 1 Immunohistochemistry in Small B-Cell Lymphomas., PMID:28395058
Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma., PMID:28109040
Fine-Tuning of the Kaposi's Sarcoma-Associated Herpesvirus Life Cycle in Neighboring Cells through the RTA-JAG1-Notch Pathway., PMID:27760204
An investigation of crosstalk between Wnt/β-catenin and transforming growth factor-β signaling in androgenetic alopecia., PMID:27472703
Charged Amino Acid-rich Leucine Zipper-1 (Crlz-1) as a Target of Wnt Signaling Pathway Controls Pre-B Cell Proliferation by Affecting Runx/CBFβ-targeted VpreB and λ5 Genes., PMID:27226553
Expression and colocalization of β-catenin and lymphoid enhancing factor-1 in prostate cancer progression., PMID:27067790
Cetuximab promotes epithelial to mesenchymal transition and cancer associated fibroblasts in patients with head and neck cancer., PMID:26437222
Factors involved in CLL pathogenesis and cell survival are disrupted by differentiation of CLL B-cells into antibody-secreting cells., PMID:26050196
Chronic lymphocytic leukemia/small lymphocytic lymphoma: another neoplasm related to the B-cell follicle?, PMID:25860247
Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development., PMID:25576928
LEF1 regulates glioblastoma cell proliferation, migration, invasion, and cancer stem-like cell self-renewal., PMID:25128061
Murine Joubert syndrome reveals Hedgehog signaling defects as a potential therapeutic target for nephronophthisis., PMID:24946806
Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility., PMID:24876153
Organized emergence of multiple-generations of teeth in snakes is dysregulated by activation of Wnt/beta-catenin signalling., PMID:24019968
Wnt11 expression in rat dental pulp and promotional effects of Wnt signaling on odontoblast differentiation., PMID:23998262
ERG is a critical regulator of Wnt/LEF1 signaling in prostate cancer., PMID:23913826
For research use only. Not for human or drug use.
